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FGF19 and FGF21: In NASH we trust

Molecular metabolism (Germany), 2021-04, Vol.46, p.101152-101152, Article 101152

2021

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Fibroblast Growth Factor 21 Limits Lipotoxicity by Promoting Hepatic Fatty Acid Activation in Mice on Methionine and Choline-Deficient Diets

Gastroenterology (New York, N.Y. 1943), 2014-11, Vol.147 (5), p.1073-1083.e6

2014

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Hepatic SIRT1 Attenuates Hepatic Steatosis and Controls Energy Balance in Mice by Inducing Fibroblast Growth Factor 21

Gastroenterology (New York, N.Y. 1943), 2014-02, Vol.146 (2), p.539-549.e7

2014

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Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State

Diabetes (New York, N.Y.), 2010-11, Vol.59 (11), p.2781-2789

2010

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Interplay between FGF21 and insulin action in the liver regulates metabolism

The Journal of clinical investigation, 2014-02, Vol.124 (2), p.515-527

2014

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Fibroblast Growth Factor 21 Corrects Obesity in Mice

Endocrinology (Philadelphia), 2008-12, Vol.149 (12), p.6018-6027

2008

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Fibroblast Growth Factor 21 (FGF21) Inhibits Chondrocyte Function and Growth Hormone Action Directly at the Growth Plate

The Journal of biological chemistry, 2012-07, Vol.287 (31), p.26060-26067

2012

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Fibroblast Growth Factor 21-Deficient Mice Demonstrate Impaired Adaptation to Ketosis

Endocrinology (Philadelphia), 2009-11, Vol.150 (11), p.4931-4940

2009

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FGF21 requires βklotho to act in vivo

PloS one, 2012-11, Vol.7 (11), p.e49977

2012

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An FGF21-Adiponectin-Ceramide Axis Controls Energy Expenditure and Insulin Action in Mice

Cell metabolism, 2013-05, Vol.17 (5), p.790-797

2013

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FGF21 is an Akt-regulated myokine

FEBS letters, 2008-11, Vol.582 (27), p.3805-3810

2008

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Central Fibroblast Growth Factor 21 Browns White Fat via Sympathetic Action in Male Mice

Endocrinology (Philadelphia), 2015-07, Vol.156 (7), p.2470-2481

2015

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Role of Fibroblast Growth Factor 21 (FGF21) in Undernutrition-Related Attenuation of Growth in Mice

Endocrinology (Philadelphia), 2012-05, Vol.153 (5), p.2287-2295

2012

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Endocrine Protection of Ischemic Myocardium by FGF21 from the Liver and Adipose Tissue

Scientific reports, 2013-09, Vol.3 (1), p.2767-2767, Article 2767

2013

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Integrated Regulation of Hepatic Metabolism by Fibroblast Growth Factor 21 (FGF21) in Vivo

Endocrinology (Philadelphia), 2011-08, Vol.152 (8), p.2996-3004

2011

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Fibroblast Growth Factor 21 Controls Glycemia via Regulation of Hepatic Glucose Flux and Insulin Sensitivity

Endocrinology (Philadelphia), 2009-09, Vol.150 (9), p.4084-4093

2009

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Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions

Diabetes (New York, N.Y.), 2013-05, Vol.62 (5), p.1453-1463

2013

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Tyrosine phosphorylation of annexin A2 regulates Rho-mediated actin rearrangement and cell adhesion

Journal of cell science, 2008-07, Vol.121 (13), p.2177-2185

2008

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The Metabolic State of Diabetic Monkeys Is Regulated by Fibroblast Growth Factor-21

Endocrinology (Philadelphia), 2007-02, Vol.148 (2), p.774-781

2007

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Fibroblast Growth Factor-21 Improves Pancreatic β-Cell Function and Survival by Activation of Extracellular Signal–Regulated Kinase 1/2 and Akt Signaling Pathways

Diabetes (New York, N.Y.), 2006-09, Vol.55 (9), p.2470-2478

2006

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Discrete Aspects of FGF21 In Vivo Pharmacology Do Not Require UCP1

Cell reports (Cambridge), 2015-05, Vol.11 (7), p.991-999

2015

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FGF21 attenuates lipolysis in human adipocytes – A possible link to improved insulin sensitivity

FEBS letters, 2008-05, Vol.582 (12), p.1725-1730

2008

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The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue

Molecular metabolism (Germany), 2013-02, Vol.2 (1), p.31-37

2013

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Naringenin Prevents Obesity, Hepatic Steatosis, and Glucose Intolerance in Male Mice Independent of Fibroblast Growth Factor 21

Endocrinology (Philadelphia), 2015-06, Vol.156 (6), p.2087-2102

2015

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LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys

PloS one, 2013-06, Vol.8 (6), p.e65763

2013

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FGF19 and FGF21: In NASH we trust

Fibroblast Growth Factor 21 Limits Lipotoxicity by Promoting Hepatic Fatty Acid Activation in Mice on Methionine and Choline-Deficient Diets

Hepatic SIRT1 Attenuates Hepatic Steatosis and Controls Energy Balance in Mice by Inducing Fibroblast Growth Factor 21

Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State

Interplay between FGF21 and insulin action in the liver regulates metabolism

Fibroblast Growth Factor 21 Corrects Obesity in Mice

Fibroblast Growth Factor 21 (FGF21) Inhibits Chondrocyte Function and Growth Hormone Action Directly at the Growth Plate

Fibroblast Growth Factor 21-Deficient Mice Demonstrate Impaired Adaptation to Ketosis

FGF21 requires βklotho to act in vivo

An FGF21-Adiponectin-Ceramide Axis Controls Energy Expenditure and Insulin Action in Mice

FGF21 is an Akt-regulated myokine

Central Fibroblast Growth Factor 21 Browns White Fat via Sympathetic Action in Male Mice

Role of Fibroblast Growth Factor 21 (FGF21) in Undernutrition-Related Attenuation of Growth in Mice

Endocrine Protection of Ischemic Myocardium by FGF21 from the Liver and Adipose Tissue

Integrated Regulation of Hepatic Metabolism by Fibroblast Growth Factor 21 (FGF21) in Vivo

Fibroblast Growth Factor 21 Controls Glycemia via Regulation of Hepatic Glucose Flux and Insulin Sensitivity

Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions

Tyrosine phosphorylation of annexin A2 regulates Rho-mediated actin rearrangement and cell adhesion

The Metabolic State of Diabetic Monkeys Is Regulated by Fibroblast Growth Factor-21

Fibroblast Growth Factor-21 Improves Pancreatic β-Cell Function and Survival by Activation of Extracellular Signal–Regulated Kinase 1/2 and Akt Signaling Pathways

Discrete Aspects of FGF21 In Vivo Pharmacology Do Not Require UCP1

FGF21 attenuates lipolysis in human adipocytes – A possible link to improved insulin sensitivity

The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue

Naringenin Prevents Obesity, Hepatic Steatosis, and Glucose Intolerance in Male Mice Independent of Fibroblast Growth Factor 21

LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys

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