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Organotypic tumor slice cultures provide a versatile platform for immuno-oncology and drug discovery

Oncoimmunology, 2019-12, Vol.8 (12), p.e1670019-e1670019

2019

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Precision-cut human liver slice cultures as an immunological platform

Journal of immunological methods, 2018-04, Vol.455, p.71-79

2018

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Livers with constitutive mTORC1 activity resist steatosis independent of feedback suppression of Akt

PloS one, 2015-02, Vol.10 (2), p.e0117000

2015

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Enhanced cAMP-stimulated protein kinase A activity in human fibrolamellar hepatocellular carcinoma

Pediatric research, 2016-07, Vol.80 (1), p.110-118

2016

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Tuberous sclerosis complex-1 deficiency attenuates diet-induced hepatic lipid accumulation

PloS one, 2011-03, Vol.6 (3), p.e18075

2011

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Chronic oral rapamycin decreases adiposity, hepatic triglycerides and insulin resistance in male mice fed a diet high in sucrose and saturated fat

Experimental physiology, 2018-11, Vol.103 (11), p.1469-1480

2018

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Altered vitamin A metabolism in human liver slices corresponds to fibrogenesis

Clinical and translational science, 2021-05, Vol.14 (3), p.976-989

2021

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An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma

eLife, 2019-05, Vol.8

2019

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Response of Human Liver Tissue to Innate Immune Stimuli

Frontiers in immunology, 2022-03, Vol.13, p.811551-811551

2022

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Latent Kaposi's Sarcoma-Associated Herpesvirus Infection of Endothelial Cells Activates Hypoxia-Induced Factors

Journal of Virology, 2006-11, Vol.80 (21), p.10802-10812

2006

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Protocol for tissue slice cultures from human solid tumors to study therapeutic response

STAR protocols, 2021-06, Vol.2 (2), p.100574-100574, Article 100574

2021

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Regulator of G-protein signaling-5 is a marker of hepatic stellate cells and expression mediates response to liver injury

PloS one, 2014-10, Vol.9 (10), p.e108505

2014

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Blockade of interleukin 10 potentiates antitumour immune function in human colorectal cancer liver metastases

Gut, 2023-02, Vol.72 (2), p.325-337

2023

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Glypican-3–Targeted 227Th α-Therapy Reduces Tumor Burden in an Orthotopic Xenograft Murine Model of Hepatocellular Carcinoma

The Journal of nuclear medicine (1978), 2022-07, Vol.63 (7), p.1033-1038

2022

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SRC inhibition enables formation of a growth suppressive MAGI1-PP2A complex in isocitrate dehydrogenase-mutant cholangiocarcinoma

Science translational medicine, 2024-05, Vol.16 (747), p.eadj7685

2024

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Production of an interleukin-10 blocking antibody by genetically engineered macrophages increases cancer cell death in human gastrointestinal tumor slice cultures

Cancer gene therapy, 2023-09, Vol.30 (9), p.1227-1233

2023

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Glucose deprivation in tuberous sclerosis complex-related tumors

Cell & bioscience, 2011-10, Vol.1 (1), p.34-34, Article 34

2011

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Glypican-3-Targeted 227 Th α -Therapy Reduces Tumor Burden in an Orthotopic Xenograft Murine Model of Hepatocellular Carcinoma

Journal of Nuclear Medicine, 2022-07, Vol.63 (7), p.1033-1038

2022

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Tuberin regulates E-cadherin localization: implications in epithelial-mesenchymal transition

The American journal of pathology, 2010-10, Vol.177 (4), p.1765-1778

2010

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Effect of immediate cold formalin fixation on phosphoprotein IHC tumor biomarker signal in liver tumors using a cold transport device

Scientific reports, 2020-02, Vol.10 (1), p.2147-2147, Article 2147

2020

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Akt and mTORC1 Have Different Roles During Liver Tumorigenesis in Mice

Gastroenterology (New York, N.Y. 1943), 2013-05, Vol.144 (5), p.1055-1065

2013

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Neurotensin as a source of cyclic AMP and co-mitogen in fibrolamellar hepatocellular carcinoma

Oncotarget, 2019-08, Vol.10 (49), p.5092-5102

2019

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Tumor slice culture as a biologic surrogate of human cancer

Annals of translational medicine, 2020-02, Vol.8 (4), p.114-114

2020

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Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors

Cancer research (Chicago, Ill.), 2002-10, Vol.62 (20), p.5645-5650

2002

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Organotypic tumor slice cultures provide a versatile platform for immuno-oncology and drug discovery

Precision-cut human liver slice cultures as an immunological platform

Livers with constitutive mTORC1 activity resist steatosis independent of feedback suppression of Akt

Enhanced cAMP-stimulated protein kinase A activity in human fibrolamellar hepatocellular carcinoma

Tuberous sclerosis complex-1 deficiency attenuates diet-induced hepatic lipid accumulation

Chronic oral rapamycin decreases adiposity, hepatic triglycerides and insulin resistance in male mice fed a diet high in sucrose and saturated fat

Altered vitamin A metabolism in human liver slices corresponds to fibrogenesis

An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma

Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms

Response of Human Liver Tissue to Innate Immune Stimuli

Latent Kaposi's Sarcoma-Associated Herpesvirus Infection of Endothelial Cells Activates Hypoxia-Induced Factors

Protocol for tissue slice cultures from human solid tumors to study therapeutic response

Regulator of G-protein signaling-5 is a marker of hepatic stellate cells and expression mediates response to liver injury

Blockade of interleukin 10 potentiates antitumour immune function in human colorectal cancer liver metastases

Glypican-3–Targeted 227Th α-Therapy Reduces Tumor Burden in an Orthotopic Xenograft Murine Model of Hepatocellular Carcinoma

SRC inhibition enables formation of a growth suppressive MAGI1-PP2A complex in isocitrate dehydrogenase-mutant cholangiocarcinoma

Production of an interleukin-10 blocking antibody by genetically engineered macrophages increases cancer cell death in human gastrointestinal tumor slice cultures

Glucose deprivation in tuberous sclerosis complex-related tumors

Glypican-3-Targeted 227 Th α -Therapy Reduces Tumor Burden in an Orthotopic Xenograft Murine Model of Hepatocellular Carcinoma

Tuberin regulates E-cadherin localization: implications in epithelial-mesenchymal transition

Effect of immediate cold formalin fixation on phosphoprotein IHC tumor biomarker signal in liver tumors using a cold transport device

Akt and mTORC1 Have Different Roles During Liver Tumorigenesis in Mice

Neurotensin as a source of cyclic AMP and co-mitogen in fibrolamellar hepatocellular carcinoma

Tumor slice culture as a biologic surrogate of human cancer

Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors

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