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A randomized, single-blind, increasing dose safety trial of an oxygen-carrying plasma expander (Hemospan®) administered to orthopaedic surgery patients with spinal anaesthesia

Transfusion medicine (Oxford, England), 2008-02, Vol.18 (1), p.28-39

2008

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Hemodilution and intravenous perflubron emulsion as an alternative to blood transfusion: effects on tissue oxygenation during profound hemodilution in anesthetized dogs

Transfusion (Philadelphia, Pa.), 1998-02, Vol.38 (2), p.145-155

1998

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Effects of hyperoxic ventilation on hemodilution-induced changes in anesthetized dogs

Transfusion (Philadelphia, Pa.), 1998-02, Vol.38 (2), p.135-144

1998

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Effect of hemoglobin- and Perflubron-based oxygen carriers on common clinical laboratory tests

Clinical chemistry (Baltimore, Md.), 1997-09, Vol.43 (9), p.1732-1737

1997

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Perflubron emulsion delays blood transfusions in orthopedic surgery

Anesthesiology (Philadelphia), 1999-11, Vol.91 (5), p.1195-1208

1999

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A Pilot Study of the Effects of a Perflubron Emulsion, AF 0104, on Mixed Venous Oxygen Tension in Anesthetized Surgical Patients

Anesthesia and analgesia, 1996-01, Vol.82 (1), p.103-107

1996

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Perflubron emulsion (Oxygent(tm)): a temporary intravenous oxygen carrier

Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2001-11, Vol.36 Suppl 2, p.S104

Keipert, P E

2001

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Randomized safety studies of intravenous perflubron emulsion. I. Effects on coagulation function in healthy volunteers

Anesthesia and analgesia, 2000-10, Vol.91 (4), p.804-811

2000

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Randomized safety studies of intravenous perflubron emulsion. II. Effects on immune function in healthy volunteers

Anesthesia and analgesia, 2000-10, Vol.91 (4), p.812-822

2000

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Acute changes in systemic blood pressure and urine output of conscious rats following exchange transfusion with diaspirin-crosslinked hemoglobin solution

Transfusion (Philadelphia, Pa.), 1993-09, Vol.33 (9), p.701-708

1993

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Effect of supplemental perfluorocarbon administration on hypotensive resuscitation of severe uncontrolled hemorrhage

The American journal of emergency medicine, 1995-05, Vol.13 (3), p.269-275

1995

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Effects of a perfluorocarbon emulsion for enhanced O2 solubility on hemodynamics and O2 transport in dogs

Journal of applied physiology (1985), 1995-11, Vol.79 (5), p.1777

1995

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Increased plasma O2 solubility improves O2 uptake of in situ dog muscle working maximally

Journal of applied physiology (1985), 1992-12, Vol.73 (6), p.2470

1992

Volltextzugriff (PDF)

Functional properties of a new crosslinked hemoglobin designed for use as a red cell substitute

Transfusion (Philadelphia, Pa.), 1989-11, Vol.29 (9), p.768-773

1989

Volltextzugriff (PDF)

Oxygen delivery augmentation by low-dose perfluorochemical emulsion during profound normovolemic hemodilution

Advances in experimental medicine and biology, 1994, Vol.345, p.197

1994

Volltextzugriff (PDF)

Normovolaemic haemodilution and hyperoxia have no effect on fractal dimension of regional myocardial perfusion in dogs

Acta physiologica Scandinavica, 1998-04, Vol.162 (4), p.439-446

1998

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Use of a PFC-based oxygen carrier to lower the transfusion trigger in a canine model of hemodilution and surgical blood loss

Advances in experimental medicine and biology, 1997, Vol.411, p.377

1997

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Evaluation of MP4OX for prevention of perioperative hypotension in patients undergoing primary hip arthroplasty with spinal anesthesia: a randomized, double-blind, multicenter study

Anesthesiology (Philadelphia), 2011-05, Vol.114 (5), p.1048-1063

2011

Volltextzugriff (PDF)

Effects of hemodilution and oxygen breathing on gut oxygenation in anesthetized dogs

Advances in experimental medicine and biology, 1997, Vol.411, p.323

1997

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A program to calculate mixed venous oxygen tension--a guide to transfusion?

Advances in experimental medicine and biology, 1994, Vol.361, p.41

1994

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Intravascular behavior of perflubron emulsions

Colloids and surfaces. A, Physicochemical and engineering aspects, 1994-04, Vol.84 (1), p.89-95

1994

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Plasma retention and metabolic fate of hemoglobin modified with an interdimeric covalent cross link

ASAIO journal (1992), 1989-04, Vol.35 (2), p.153-159

1989

Volltextzugriff (PDF)

A double-blind, randomized, multicenter study of MP4OX for treatment of perioperative hypotension in patients undergoing primary hip arthroplasty under spinal anesthesia

Anesthesia and analgesia, 2011-04, Vol.112 (4), p.759-773

2011

Volltextzugriff (PDF)

Preparation and in vitro characteristics of a blood substitute based on pyridoxylated polyhemoglobin

Applied biochemistry and biotechnology, 1984-02, Vol.10 (1-3), p.133-141

1984

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Whole animal, lung and muscle hemodynamics and function are maintained during and after Oxygent HT infusion

Advances in experimental medicine and biology, 1994, Vol.361, p.313

1994

Volltextzugriff (PDF)

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Rats
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A randomized, single-blind, increasing dose safety trial of an oxygen-carrying plasma expander (Hemospan®) administered to orthopaedic surgery patients with spinal anaesthesia

Hemodilution and intravenous perflubron emulsion as an alternative to blood transfusion: effects on tissue oxygenation during profound hemodilution in anesthetized dogs

Effects of hyperoxic ventilation on hemodilution-induced changes in anesthetized dogs

Effect of hemoglobin- and Perflubron-based oxygen carriers on common clinical laboratory tests

Perflubron emulsion delays blood transfusions in orthopedic surgery

A Pilot Study of the Effects of a Perflubron Emulsion, AF 0104, on Mixed Venous Oxygen Tension in Anesthetized Surgical Patients

Perflubron emulsion (Oxygent(tm)): a temporary intravenous oxygen carrier

Randomized safety studies of intravenous perflubron emulsion. I. Effects on coagulation function in healthy volunteers

Randomized safety studies of intravenous perflubron emulsion. II. Effects on immune function in healthy volunteers

Acute changes in systemic blood pressure and urine output of conscious rats following exchange transfusion with diaspirin-crosslinked hemoglobin solution

Effect of supplemental perfluorocarbon administration on hypotensive resuscitation of severe uncontrolled hemorrhage

Effects of a perfluorocarbon emulsion for enhanced O2 solubility on hemodynamics and O2 transport in dogs

Increased plasma O2 solubility improves O2 uptake of in situ dog muscle working maximally

Functional properties of a new crosslinked hemoglobin designed for use as a red cell substitute

Oxygen delivery augmentation by low-dose perfluorochemical emulsion during profound normovolemic hemodilution

Normovolaemic haemodilution and hyperoxia have no effect on fractal dimension of regional myocardial perfusion in dogs

Use of a PFC-based oxygen carrier to lower the transfusion trigger in a canine model of hemodilution and surgical blood loss

Evaluation of MP4OX for prevention of perioperative hypotension in patients undergoing primary hip arthroplasty with spinal anesthesia: a randomized, double-blind, multicenter study

Effects of hemodilution and oxygen breathing on gut oxygenation in anesthetized dogs

A program to calculate mixed venous oxygen tension--a guide to transfusion?

Intravascular behavior of perflubron emulsions

Plasma retention and metabolic fate of hemoglobin modified with an interdimeric covalent cross link

A double-blind, randomized, multicenter study of MP4OX for treatment of perioperative hypotension in patients undergoing primary hip arthroplasty under spinal anesthesia

Preparation and in vitro characteristics of a blood substitute based on pyridoxylated polyhemoglobin

Whole animal, lung and muscle hemodynamics and function are maintained during and after Oxygent HT infusion

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