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From acute ER stress to physiological roles of the Unfolded Protein Response

Cell death and differentiation, 2006-03, Vol.13 (3), p.374-384

2006

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Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

Genes & development, 1999-05, Vol.13 (10), p.1211-1233

Kaufman, R J

1999

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ER stress (PERK eIF2 phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation

Cell death and differentiation, 2007-02, Vol.14 (2), p.230-239

2007

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Adaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbations

Brain research, 2016-10, Vol.1648 (Pt B), p.603-616

2016

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ER stress and its functional link to mitochondria: role in cell survival and death

Cold Spring Harbor perspectives in biology, 2011-09, Vol.3 (9), p.a004424-a004424

2011

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Ligand-independent Dimerization Activates the Stress Response Kinases IRE1 and PERK in the Lumen of the Endoplasmic Reticulum

The Journal of biological chemistry, 2000-08, Vol.275 (32), p.24881-24885

2000

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The mammalian unfolded protein response

Annual review of biochemistry, 2005-01, Vol.74 (1), p.739-789

2005

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Double-Stranded RNA-Activated Protein Kinase Mediates Virus-Induced Apoptosis: A New Role for an Old Actor

Proceedings of the National Academy of Sciences - PNAS, 1999-10, Vol.96 (21), p.11693-11695

Kaufman, Randal J.

1999

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ER stress signalling through eIF2α and CHOP, but not IRE1α, attenuates adipogenesis in mice

Diabetologia, 2013-04, Vol.56 (4), p.911-924

2013

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unfolded protein response is required to maintain the integrity of the endoplasmic reticulum, prevent oxidative stress and preserve differentiation in β-cells

Diabetes, obesity & metabolism, 2010-10, Vol.12 (s2), p.99-107

2010

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Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival

Molecular and Cellular Biology, 2003-10, Vol.23 (20), p.7198-7209

2003

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Phosphorylation of Serine 51 in Initiation Factor 2α (eIF2α) Promotes Complex Formation between eIF2α(P) and eIF2B and Causes Inhibition in the Guanine Nucleotide Exchange Activity of eIF2B

Biochemistry (Easton), 2000-10, Vol.39 (42), p.12929-12938

2000

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Advances toward gene therapy for hemophilia at the millennium

Human gene therapy, 1999-09, Vol.10 (13), p.2091-2107

KAUFMAN, R. J

1999

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Post-translational modifications required for coagulation factor secretion and function

Thrombosis and haemostasis, 1998, Vol.79 (6), p.1068

Kaufman, R J

1998

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Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation

The Journal of biological chemistry, 2003-06, Vol.278 (23), p.20915-20924

2003

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Rare bleeding disorders

Haemophilia : the official journal of the World Federation of Hemophilia, 2006-07, Vol.12 (s3), p.137-142

2006

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Regulation of mRNA translation by protein folding in the endoplasmic reticulum

Trends in biochemical sciences (Amsterdam. Regular ed.), 2004-03, Vol.29 (3), p.152-158

Kaufman, Randal J

2004

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Protein folding in the endoplasmic reticulum and the unfolded protein response

Handbook of experimental pharmacology, 2006 (172), p.69

2006

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Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis

Nature medicine, 2005-07, Vol.11 (7), p.757-764

2005

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Translational Control Is Required for the Unfolded Protein Response and In Vivo Glucose Homeostasis

Molecular cell, 2001-06, Vol.7 (6), p.1165-1176

2001

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Mild hemophilia A caused by increased rate of factor VIII A2 subunit dissociation : Evidence for nonproteolytic inactivation of factor VIIIa in vivo

Blood, 1999, Vol.93 (1), p.176-183

1999

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The E3L and K3L vaccinia virus gene products stimulate translation through inhibition of the double-stranded RNA-dependent protein kinase by different mechanisms

Journal of Virology, 1993-03, Vol.67 (3), p.1688-1692

1993

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Biochemical, immunological, and in vivo functional characterization of B-domain-deleted factor VIII

Blood, 1993-06, Vol.81 (11), p.2925-2935

1993

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The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4

Nature, 2004-03, Vol.428 (6980), p.341-345

2004

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Moderation of hemophilia A phenotype by the factor V R506Q mutation

Blood, 1996-08, Vol.88 (4), p.1183-1187

1996

Volltextzugriff (PDF)

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