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Prokinetic effects of the neurokinin NK2 receptor agonist [Lys5,MeLeu9,Nle10]-NKA(4–10) on bladder and colorectal activity in minipigs

Neuropeptides (Edinburgh), 2019-10, Vol.77, p.101956-101956, Article 101956

2019

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Recent Developments in On-Demand Voiding Therapies

The Journal of pharmacology and experimental therapeutics, 2024-08, Vol.390 (3), p.302-317

2024

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Chronic, Twice-Daily Dosing of an NK2 Receptor Agonist [Lys 5 ,MeLeu 9 ,Nle 10 ]-NKA(4-10), Produces Consistent Drug-Induced Micturition and Defecation in Chronic Spinal Rats

Journal of neurotrauma, 2020-03, Vol.37 (6), p.868-876

2020

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Colorectal and bladder prokinetic activity of [Lys 5 , MeLeu 9 , Nle 10 ]-NKA (4-10) after intranasal or sublingual delivery in dogs

Canadian journal of physiology and pharmacology, 2023-04, Vol.101 (4), p.171-179

2023

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Comparison of the effects of serotonin selective, norepinephrine selective, and dual serotonin and norepinephrine reuptake inhibitors on lower urinary tract function in cats

Life sciences (1973), 2002-08, Vol.71 (11), p.1227-1236

2002

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The role of 5-HT1A receptors in control of lower urinary tract function in cats

Brain research, 2002-08, Vol.946 (2), p.290-297

2002

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Ethyl (3S,4aR,6S,8aR)-6-(4-Ethoxycar- bonylimidazol-1-ylmethyl)decahydroiso- quinoline-3-carboxylic Ester: A Prodrug of a GluR5 Kainate Receptor Antagonist Active in Two Animal Models of Acute Migraine

Journal of medicinal chemistry, 2002-09, Vol.45 (20), p.4383-4386

2002

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1371: Chronic Real-Time Ambulatory Urodynamics in Cats Using Radio Telemetry for Drug Screening

The Journal of urology, 2006-04, Vol.175 (4), p.442-442

2006

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195: Effects of a Combined 5HT3 Receptor Antagonist and Noradrenaline Reuptake Inhibitor on Lower Urinary Tract Activity

The Journal of urology, 2006-04, Vol.175 (4), p.63-64

2006

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The role of 5-HT(1A) receptors in control of lower urinary tract function in cats

Brain research, 2002-08, Vol.946 (2), p.290-297

2002

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Extrinsic Innervation of the Cat Prostate Gland: A Combined Tracing and Immunohistochemical Study

The Journal of urology, 1997-03, Vol.157 (3), p.1018-1024

1997

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The role of 5-HT 1A receptors in control of lower urinary tract function in cats

Brain research, 2002, Vol.946 (2), p.290-297

2002

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Extrinsic Innervation of the Cat Prostate Gland: A Combined Tracing and Immunohistochemical Study

The Journal of urology, 1997-03, p.1018-1024

1997

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Sa1667 – Use of [Lys5, Meleu9,NLE10]-NKA(4–10) (LMN-NKA) as a Rapid-Onset, Short-Duration, Drug-Induced, Defecation Therapy IN Chronic Spinal Rats Across 30 Days of Subcutaneous B.I.D. Administration

Gastroenterology (New York, N.Y. 1943), 2019-05, Vol.156 (6), p.S-359-S-360

2019

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[Lys 5 ,MeLeu 9 ,Nle 10 ]-NKA (4–10) Elicits NK2 Receptor–Mediated Micturition and Defecation, and NK1 Receptor–Mediated Emesis and Hypotension, in Conscious Dogs

The Journal of pharmacology and experimental therapeutics, 2018-07, Vol.366 (1), p.136-144

2018

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Sa1668 – On-Demand, Drug-Induced Defecation Following Intravenous (IV), Subcutaneous (SC), Intranasal (IN), Or Sublingual (SL) Administration of [Lys5,MELEU9,NLE10]-Neurokinin A(4–10) (LMN-NKA) to Minipigs

Gastroenterology (New York, N.Y. 1943), 2019-05, Vol.156 (6), p.S-360-S-360

2019

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NK2 and NK1 receptor-mediated effects of NKA and analogs on colon, bladder, and arterial pressure in anesthetized dogs

Naunyn-Schmiedeberg's archives of pharmacology, 2018-03, Vol.391 (3), p.299-308

2018

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Prokinetic effects of neurokinin-2 receptor agonists on the bladder and rectum of rats with acute spinal cord transection

European journal of pharmacology, 2018-01, Vol.819, p.261-269

2018

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Colorectal and cardiovascular effects of [Lys5,MeLeu9,Nle10]-NKA(4-10) in anesthetized macaques

Naunyn-Schmiedeberg's archives of pharmacology, 2018-09, Vol.391 (9), p.907-914

2018

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Pharmacological characterization of the competitive GLUK5 receptor antagonist decahydroisoquinoline LY466195 in vitro and in vivo

The Journal of pharmacology and experimental therapeutics, 2006-08, Vol.318 (2), p.772

2006

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Pharmacological Characterization of the Competitive GLU K5 Receptor Antagonist Decahydroisoquinoline LY466195 in Vitro and in Vivo

The Journal of pharmacology and experimental therapeutics, 2006-08, Vol.318 (2), p.772-781

2006

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Prokinetic effects of the neurokinin NK2 receptor agonist [Lys5,MeLeu9,Nle10]-NKA(4–10) on bladder and colorectal activity in minipigs

Recent Developments in On-Demand Voiding Therapies

Chronic, Twice-Daily Dosing of an NK2 Receptor Agonist [Lys 5 ,MeLeu 9 ,Nle 10 ]-NKA(4-10), Produces Consistent Drug-Induced Micturition and Defecation in Chronic Spinal Rats

Colorectal and bladder prokinetic activity of [Lys 5 , MeLeu 9 , Nle 10 ]-NKA (4-10) after intranasal or sublingual delivery in dogs

Comparison of the effects of serotonin selective, norepinephrine selective, and dual serotonin and norepinephrine reuptake inhibitors on lower urinary tract function in cats

The role of 5-HT1A receptors in control of lower urinary tract function in cats

Ethyl (3S,4aR,6S,8aR)-6-(4-Ethoxycar- bonylimidazol-1-ylmethyl)decahydroiso- quinoline-3-carboxylic Ester: A Prodrug of a GluR5 Kainate Receptor Antagonist Active in Two Animal Models of Acute Migraine

1371: Chronic Real-Time Ambulatory Urodynamics in Cats Using Radio Telemetry for Drug Screening

195: Effects of a Combined 5HT3 Receptor Antagonist and Noradrenaline Reuptake Inhibitor on Lower Urinary Tract Activity

The role of 5-HT(1A) receptors in control of lower urinary tract function in cats

Extrinsic Innervation of the Cat Prostate Gland: A Combined Tracing and Immunohistochemical Study

The role of 5-HT 1A receptors in control of lower urinary tract function in cats

Ethyl (3S, 4aR, 6S, 8aR)-6-(4-ethoxycarbonylimidazol-1-ylmethyl)decahydroisoquinoline-3-c arboxylic ester: A prodrug of a GluR5 kainate receptor antagonist active in two animal models of acute migraine

Extrinsic Innervation of the Cat Prostate Gland: A Combined Tracing and Immunohistochemical Study

Sa1667 – Use of [Lys5, Meleu9,NLE10]-NKA(4–10) (LMN-NKA) as a Rapid-Onset, Short-Duration, Drug-Induced, Defecation Therapy IN Chronic Spinal Rats Across 30 Days of Subcutaneous B.I.D. Administration

[Lys 5 ,MeLeu 9 ,Nle 10 ]-NKA (4–10) Elicits NK2 Receptor–Mediated Micturition and Defecation, and NK1 Receptor–Mediated Emesis and Hypotension, in Conscious Dogs

Sa1668 – On-Demand, Drug-Induced Defecation Following Intravenous (IV), Subcutaneous (SC), Intranasal (IN), Or Sublingual (SL) Administration of [Lys5,MELEU9,NLE10]-Neurokinin A(4–10) (LMN-NKA) to Minipigs

NK2 and NK1 receptor-mediated effects of NKA and analogs on colon, bladder, and arterial pressure in anesthetized dogs

Prokinetic effects of neurokinin-2 receptor agonists on the bladder and rectum of rats with acute spinal cord transection

Colorectal and cardiovascular effects of [Lys5,MeLeu9,Nle10]-NKA(4-10) in anesthetized macaques

Pharmacological characterization of the competitive GLUK5 receptor antagonist decahydroisoquinoline LY466195 in vitro and in vivo

Pharmacological Characterization of the Competitive GLU K5 Receptor Antagonist Decahydroisoquinoline LY466195 in Vitro and in Vivo

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