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S119: PRELIMINARY RESULTS OF A PHASE 1 STUDY IN HEALTHY SUBJECTS ADMINISTERED INCLACUMAB, A FULLY HUMAN IGG4 ANTI‐P‐SELECTIN MONOCLONAL ANTIBODY IN DEVELOPMENT FOR TREATMENT OF SICKLE CELL DISEASE

HemaSphere, 2022-01, Vol.6 (Suppl), p.10-10

2022

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Randomised, parallel-group, multicentre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillation

Thrombosis and haemostasis, 2010-09, Vol.104 (3), p.633-641

2010

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A phase I and pharmacokinetic study of irinotecan in patients with hepatic or renal dysfunction or with prior pelvic radiation: CALGB 9863

Annals of oncology, 2003-12, Vol.14 (12), p.1783-1790

2003

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Modelling and simulation of edoxaban exposure and response relationships in patients with atrial fibrillation

Thrombosis and haemostasis, 2012-05, Vol.107 (5), p.925-934

2012

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Development of a Predictive Pharmacokinetic Model for a Novel Cyclooxygenase-2 Inhibitor

Journal of clinical pharmacology, 2006-05, Vol.46 (5), p.537-548

2006

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Predictive Population Pharmacokinetic/Pharmacodynamic Model for a Novel COX-2 Inhibitor

Journal of clinical pharmacology, 2007-03, Vol.47 (3), p.358-370

2007

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Characterisation of exposure versus response of edoxaban in patients undergoing total hip replacement surgery

Thrombosis and haemostasis, 2012-11, Vol.108 (5), p.887-895

2012

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Medication compliance as a feature in drug development

Annual review of pharmacology and toxicology, 1997-01, Vol.37 (1), p.451-475

1997

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Modeling and simulation of bone mineral density response from a phase 2 study of ONO-5334, a new cathepsin K inhibitor, to support dose selection in osteoporosis

Journal of clinical pharmacology, 2014-08, Vol.54 (8), p.937-948

2014

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Pharmacokinetics of diaspirin cross-linked haemoglobin in a rat model of hepatic cirrhosis

Journal of pharmacy and pharmacology, 2001-02, Vol.53 (2), p.179-185

2001

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Exposure-Response Relationship to Assess the Risk of Neutropenia in Patients with Hepatocellular Carcinoma (HCC) Treated with Tivantinib

Annals of oncology, 2012-09, Vol.23, p.ix244-ix245

2012

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Pharmacokinetics of saquinavir, zidovudine, and zalcitabine in combination therapy

Antimicrobial Agents and Chemotherapy, 1997-11, Vol.41 (11), p.2428-2432

1997

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A Pharmacokinetic (PK) Model for Irinotecan and Its Metabolites in Cancer Patients

Clinical pharmacology and therapeutics, 1999-02, Vol.65 (2), p.197-197

1999

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Population pharmacokinetic model for irinotecan and two of its metabolites, SN-38 and SN-38 glucuronide

Clinical pharmacology and therapeutics, 2002-12, Vol.72 (6), p.638-647

2002

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Pharmacokinetics of high-dose oral CCNU in bone marrow transplant patients

Cancer chemotherapy and pharmacology, 1996, Vol.38 (5), p.425-430

1996

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Characterizing patterns of drug-taking behavior with a multiple drug regimen in an AIDS clinical trial

AIDS (London), 1998-12, Vol.12 (17), p.2295-2303

1998

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A Markov mixed effect regression model for drug compliance

Statistics in medicine, 1998-10, Vol.17 (20), p.2313-2333

1998

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Pharmacokinetics, pharmacodynamics and adherence to oral topotecan in myelodysplastic syndromes : a Cancer and Leukemia Group B study

Cancer chemotherapy and pharmacology, 2006-02, Vol.57 (2), p.199-206

2006

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Plasma concentrations of bupivacaine after wound infiltration of an 0.5 % solution after inguinal herniorrhaphy : a preliminary study

European journal of clinical pharmacology, 1993-07, Vol.44 (6), p.555-557

1993

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Disposition of morphine in plasma and cerebrospinal fluid varies during neonatal development in pigs

Journal of pharmacy and pharmacology, 2005-08, Vol.57 (8), p.981-985

2005

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Phase I and Pharmacokinetic Study of Irinotecan and Docetaxel in Patients With Advanced Solid Tumors: Preliminary Evidence of Clinical Activity

Journal of clinical oncology, 2000-03, Vol.18 (5), p.1116-1123

2000

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The extent of non-adherence in a large AIDS clinical trial using plasma dideoxynucleoside concentrations as a marker

AIDS (London), 1998-12, Vol.12 (17), p.2305-2311

1998

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The effect of rifaximin on the pharmacokinetics (PK) of single doses of intravenous (IV) and oral (PO) midazolam in healthy volunteers

Clinical pharmacology and therapeutics, 2004-02, Vol.75 (2), p.P66-P66

2004

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The effect of rifaximin on the pharmacokinetics of a single dose of ethinyl estradiol and norgestimate in healthy female volunteers

Clinical pharmacology and therapeutics, 2004-02, Vol.75 (2), p.P96-P96

2004

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The pharmacokinetics and pharmacodynamics of docetaxel (DCTX) in Caucasian and African American patients with solid tumors

Journal of clinical oncology, 2004-07, Vol.22 (14_suppl), p.2043-2043

2004

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S119: PRELIMINARY RESULTS OF A PHASE 1 STUDY IN HEALTHY SUBJECTS ADMINISTERED INCLACUMAB, A FULLY HUMAN IGG4 ANTI‐P‐SELECTIN MONOCLONAL ANTIBODY IN DEVELOPMENT FOR TREATMENT OF SICKLE CELL DISEASE

Randomised, parallel-group, multicentre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillation

A phase I and pharmacokinetic study of irinotecan in patients with hepatic or renal dysfunction or with prior pelvic radiation: CALGB 9863

Modelling and simulation of edoxaban exposure and response relationships in patients with atrial fibrillation

Development of a Predictive Pharmacokinetic Model for a Novel Cyclooxygenase-2 Inhibitor

Predictive Population Pharmacokinetic/Pharmacodynamic Model for a Novel COX-2 Inhibitor

Characterisation of exposure versus response of edoxaban in patients undergoing total hip replacement surgery

Medication compliance as a feature in drug development

Modeling and simulation of bone mineral density response from a phase 2 study of ONO-5334, a new cathepsin K inhibitor, to support dose selection in osteoporosis

Pharmacokinetics of diaspirin cross-linked haemoglobin in a rat model of hepatic cirrhosis

Exposure-Response Relationship to Assess the Risk of Neutropenia in Patients with Hepatocellular Carcinoma (HCC) Treated with Tivantinib

Pharmacokinetics of saquinavir, zidovudine, and zalcitabine in combination therapy

A Pharmacokinetic (PK) Model for Irinotecan and Its Metabolites in Cancer Patients

Population pharmacokinetic model for irinotecan and two of its metabolites, SN-38 and SN-38 glucuronide

Pharmacokinetics of high-dose oral CCNU in bone marrow transplant patients

Characterizing patterns of drug-taking behavior with a multiple drug regimen in an AIDS clinical trial

A Markov mixed effect regression model for drug compliance

Pharmacokinetics, pharmacodynamics and adherence to oral topotecan in myelodysplastic syndromes : a Cancer and Leukemia Group B study

Plasma concentrations of bupivacaine after wound infiltration of an 0.5 % solution after inguinal herniorrhaphy : a preliminary study

Disposition of morphine in plasma and cerebrospinal fluid varies during neonatal development in pigs

Phase I and Pharmacokinetic Study of Irinotecan and Docetaxel in Patients With Advanced Solid Tumors: Preliminary Evidence of Clinical Activity

The extent of non-adherence in a large AIDS clinical trial using plasma dideoxynucleoside concentrations as a marker

The effect of rifaximin on the pharmacokinetics (PK) of single doses of intravenous (IV) and oral (PO) midazolam in healthy volunteers

The effect of rifaximin on the pharmacokinetics of a single dose of ethinyl estradiol and norgestimate in healthy female volunteers

The pharmacokinetics and pharmacodynamics of docetaxel (DCTX) in Caucasian and African American patients with solid tumors

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