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The 1918 influenza pandemic: 100 years of questions answered and unanswered

Science translational medicine, 2019-07, Vol.11 (502)

2019

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The Role of Viral, Host, and Secondary Bacterial Factors in Influenza Pathogenesis

The American journal of pathology, 2015-06, Vol.185 (6), p.1528-1536

2015

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Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19

Science translational medicine, 2021-11, Vol.13 (620), p.eabj7790

2021

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Identification of a novel splice variant form of the influenza A virus M2 ion channel with an antigenically distinct ectodomain

PLoS pathogens, 2012-11, Vol.8 (11), p.e1002998-e1002998

2012

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Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus

Nature, 2006-10, Vol.443 (7111), p.578-581

2006

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Autopsy series of 68 cases dying before and during the 1918 influenza pandemic peak

Proceedings of the National Academy of Sciences - PNAS, 2011-09, Vol.108 (39), p.16416-16421

2011

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An Intranasal Virus-Like Particle Vaccine Broadly Protects Mice from Multiple Subtypes of Influenza A Virus

mBio, 2015-07, Vol.6 (4), p.e01044-e01044

2015

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Mucosal correlates of protection after influenza viral challenge of vaccinated and unvaccinated healthy volunteers

mBio, 2024-02, Vol.15 (2), p.e0237223-e0237223

2024

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Influenza virus evolution, host adaptation, and pandemic formation

Cell host & microbe, 2010-06, Vol.7 (6), p.440-451

2010

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High-throughput RNA sequencing of a formalin-fixed, paraffin-embedded autopsy lung tissue sample from the 1918 influenza pandemic

The Journal of pathology, 2013-03, Vol.229 (4), p.535-545

2013

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Virus infection of the CNS disrupts the immune-neural-synaptic axis via induction of pleiotropic gene regulation of host responses

eLife, 2021-02, Vol.10

2021

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Global Suppression of the Host Antiviral Response by Ebola- and Marburgviruses: Increased Antagonism of the Type I Interferon Response Is Associated with Enhanced Virulence

Journal of Virology, 2006-03, Vol.80 (6), p.3009-3020

2006

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Lethal synergism of 2009 pandemic H1N1 influenza virus and Streptococcus pneumoniae coinfection is associated with loss of murine lung repair responses

mBio, 2011, Vol.2 (5)

2011

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Role of Sialic Acid Binding Specificity of the 1918 Influenza Virus Hemagglutinin Protein in Virulence and Pathogenesis for Mice

Journal of Virology, 2009-04, Vol.83 (8), p.3754-3761

2009

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Analysis by Single-Gene Reassortment Demonstrates that the 1918 Influenza Virus Is Functionally Compatible with a Low-Pathogenicity Avian Influenza Virus in Mice

Journal of Virology, 2012-09, Vol.86 (17), p.9211-9220

2012

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An early ‘classical’ swine H1N1 influenza virus shows similar pathogenicity to the 1918 pandemic virus in ferrets and mice

Virology (New York, N.Y.), 2009-10, Vol.393 (2), p.338-345

2009

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The effect of calcium and magnesium on activity, immunogenicity, and efficacy of a recombinant N1/N2 neuraminidase vaccine

npj vaccines, 2021-04, Vol.6 (1), p.48-48, Article 48

2021

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More autopsy studies are needed to understand the pathogenesis of severe COVID-19

Nature medicine, 2022-03, Vol.28 (3), p.427-428

2022

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Global Host Immune Response: Pathogenesis and Transcriptional Profiling of Type A Influenza Viruses Expressing the Hemagglutinin and Neuraminidase Genes from the 1918 Pandemic Virus

Journal of Virology, 2004-09, Vol.78 (17), p.9499-9511

2004

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Contemporary avian influenza A virus subtype H1, H6, H7, H10, and H15 hemagglutinin genes encode a mammalian virulence factor similar to the 1918 pandemic virus H1 hemagglutinin

mBio, 2014-11, Vol.5 (6), p.e02116-e02116

2014

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Influenza A Reinfection in Sequential Human Challenge: Implications for Protective Immunity and “Universal” Vaccine Development

Clinical infectious diseases, 2020-02, Vol.70 (5), p.748-753

2020

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Suppression of Proinflammatory Signal Transduction and Gene Expression by the Dual Nucleic Acid Binding Domains of the Vaccinia Virus E3L Proteins

Journal of Virology, 2006-10, Vol.80 (20), p.10083-10095

2006

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Deep Sequencing of H7N9 Influenza A Viruses from 16 Infected Patients from 2013 to 2015 in Shanghai Reveals Genetic Diversity and Antigenic Drift

mSphere, 2018-09, Vol.3 (5)

2018

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Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus

Nature, 2007-01, Vol.445 (7125), p.319-323

2007

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The 1918 influenza pandemic: 100 years of questions answered and unanswered

The Role of Viral, Host, and Secondary Bacterial Factors in Influenza Pathogenesis

Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19

Identification of a novel splice variant form of the influenza A virus M2 ion channel with an antigenically distinct ectodomain

Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus

Autopsy series of 68 cases dying before and during the 1918 influenza pandemic peak

An Intranasal Virus-Like Particle Vaccine Broadly Protects Mice from Multiple Subtypes of Influenza A Virus

Mucosal correlates of protection after influenza viral challenge of vaccinated and unvaccinated healthy volunteers

Influenza virus evolution, host adaptation, and pandemic formation

High-throughput RNA sequencing of a formalin-fixed, paraffin-embedded autopsy lung tissue sample from the 1918 influenza pandemic

Virus infection of the CNS disrupts the immune-neural-synaptic axis via induction of pleiotropic gene regulation of host responses

Global Suppression of the Host Antiviral Response by Ebola- and Marburgviruses: Increased Antagonism of the Type I Interferon Response Is Associated with Enhanced Virulence

Lethal synergism of 2009 pandemic H1N1 influenza virus and Streptococcus pneumoniae coinfection is associated with loss of murine lung repair responses

Role of Sialic Acid Binding Specificity of the 1918 Influenza Virus Hemagglutinin Protein in Virulence and Pathogenesis for Mice

Differential Effects of Influenza Virus NA, HA Head, and HA Stalk Antibodies on Peripheral Blood Leukocyte Gene Expression during Human Infection

Analysis by Single-Gene Reassortment Demonstrates that the 1918 Influenza Virus Is Functionally Compatible with a Low-Pathogenicity Avian Influenza Virus in Mice

An early ‘classical’ swine H1N1 influenza virus shows similar pathogenicity to the 1918 pandemic virus in ferrets and mice

The effect of calcium and magnesium on activity, immunogenicity, and efficacy of a recombinant N1/N2 neuraminidase vaccine

More autopsy studies are needed to understand the pathogenesis of severe COVID-19

Global Host Immune Response: Pathogenesis and Transcriptional Profiling of Type A Influenza Viruses Expressing the Hemagglutinin and Neuraminidase Genes from the 1918 Pandemic Virus

Contemporary avian influenza A virus subtype H1, H6, H7, H10, and H15 hemagglutinin genes encode a mammalian virulence factor similar to the 1918 pandemic virus H1 hemagglutinin

Influenza A Reinfection in Sequential Human Challenge: Implications for Protective Immunity and “Universal” Vaccine Development

Suppression of Proinflammatory Signal Transduction and Gene Expression by the Dual Nucleic Acid Binding Domains of the Vaccinia Virus E3L Proteins

Deep Sequencing of H7N9 Influenza A Viruses from 16 Infected Patients from 2013 to 2015 in Shanghai Reveals Genetic Diversity and Antigenic Drift

Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus

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