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A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa

Nature medicine, 2013-04, Vol.19 (4), p.446-451

2013

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Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors

Blood advances, 2018-08, Vol.2 (16), p.2104-2114

2018

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Biochemical and Biological Properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a Mechanism-Based Inhibitor of Fatty Acid Amide Hydrolase

Anesthesia and analgesia, 2009, Vol.108 (1), p.316-329

2009

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Purification and Characterization of the Lipid A 1-Phosphatase LpxE of Rhizobium leguminosarum

The Journal of biological chemistry, 2009-01, Vol.284 (1), p.414-425

2009

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Periplasmic Cleavage and Modification of the 1-Phosphate Group of Helicobacter pylori Lipid A

The Journal of biological chemistry, 2004-12, Vol.279 (53), p.55780-55791

2004

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Expression Cloning and Biochemical Characterization of a Rhizobium leguminosarum Lipid A 1-Phosphatase

The Journal of biological chemistry, 2003-10, Vol.278 (41), p.39269-39279

2003

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A phase 2 PK/PD study of andexanet alfa for reversal of rivaroxaban and edoxaban anticoagulation in healthy volunteers

Blood advances, 2020-02, Vol.4 (4), p.728-739

2020

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Expression Cloning and Characterization of the C28 Acyltransferase of Lipid A Biosynthesis in Rhizobium leguminosarum

The Journal of biological chemistry, 2002-08, Vol.277 (32), p.28959-28971

2002

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Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amide hydrolase

Bioorganic & medicinal chemistry, 2008-09, Vol.18 (17), p.4838-4843

2008

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Interaction of Group IA Phospholipase A2 with Metal Ions and Phospholipid Vesicles Probed with Deuterium Exchange Mass Spectrometry

Biochemistry (Easton), 2008-06, Vol.47 (24), p.6451-6459

2008

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Heteroarylureas with spirocyclic diamine cores as inhibitors of fatty acid amide hydrolase

Bioorganic & medicinal chemistry letters, 2014-02, Vol.24 (3), p.737-741

2014

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MsbA transporter-dependent lipid A 1-dephosphorylation on the periplasmic surface of the inner membrane: topography of francisella novicida LpxE expressed in Escherichia coli

The Journal of biological chemistry, 2004-11, Vol.279 (47), p.49470-49478

2004

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1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase

Bioorganic & medicinal chemistry letters, 2014-03, Vol.24 (5), p.1280-1284

2014

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Heteroaryl urea inhibitors of fatty acid amide hydrolase: Structure–mutagenicity relationships for arylamine metabolites

Bioorganic & medicinal chemistry letters, 2012-12, Vol.22 (24), p.7357-7362

2012

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Enzymatic synthesis of lipid A molecules with four amide-linked acyl chains. LpxA acyltransferases selective for an analog of UDP-N-acetylglucosamine in which an amine replaces the 3"-hydroxyl group

The Journal of biological chemistry, 2004-06, Vol.279 (24), p.25411-25419

2004

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Origin of the 2-amino-2-deoxy-gluconate unit in Rhizobium leguminosarum lipid A. Expression cloning of the outer membrane oxidase LpxQ

The Journal of biological chemistry, 2003-04, Vol.278 (14), p.12120-12129

2003

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MsbA Transporter-dependent Lipid A 1-Dephosphorylation on the Periplasmic Surface of the Inner Membrane

The Journal of biological chemistry, 2004-11, Vol.279 (47), p.49470-49478

2004

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Enzymatic Synthesis of Lipid A Molecules with Four Amide-linked Acyl Chains

The Journal of biological chemistry, 2004-06, Vol.279 (24), p.25411-25419

2004

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Origin of the 2-Amino-2-deoxy-gluconate Unit inRhizobium leguminosarum Lipid A

The Journal of biological chemistry, 2003-04, Vol.278 (14), p.12120-12129

2003

Volltextzugriff (PDF)

Purification and Characterization of the Lipid A 1-Phosphatase LpxE of Rhizobium leguminosarumS

The Journal of biological chemistry, 2009-01, Vol.284 (1), p.414-425

2009

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Heteroaryl urea inhibitors of fatty acid amide hydrolase: Structureamutagenicity relationships for arylamine metabolites

Bioorganic & medicinal chemistry letters, 2012-12, Vol.22 (24), p.7357-7362

2012

Volltextzugriff (PDF)

Interaction of Group IA Phospholipase A 2 with Metal Ions and Phospholipid Vesicles Probed with Deuterium Exchange Mass Spectrometry

Biochemistry (Easton), 2008-06, Vol.47 (24), p.6451-6459

2008

Volltextzugriff (PDF)

Interaction of Group IA Phospholipase A sub(2) with Metal Ions and Phospholipid Vesicles Probed with Deuterium Exchange Mass Spectrometry

Biochemistry (Easton), 2008-01, Vol.47 (24), p.6451-6459

2008

Volltextzugriff (PDF)

Enzymatic Synthesis of Lipid A Molecules with Four Amide-linked Acyl Chains: LpxA Acyltransferases Selective for an Analog of UDP

The Journal of biological chemistry, 2004-03, Vol.279 (24), p.25411-25419

2004

Volltextzugriff (PDF)

Heteroarylureas with fused bicyclic diamine cores as inhibitors of fatty acid amide hydrolase

Bioorganic & medicinal chemistry letters, 2020-10, Vol.30 (20), p.127463-127463, Article 127463

2020

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A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa

Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors

Biochemical and Biological Properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a Mechanism-Based Inhibitor of Fatty Acid Amide Hydrolase

Purification and Characterization of the Lipid A 1-Phosphatase LpxE of Rhizobium leguminosarum

Periplasmic Cleavage and Modification of the 1-Phosphate Group of Helicobacter pylori Lipid A

Expression Cloning and Biochemical Characterization of a Rhizobium leguminosarum Lipid A 1-Phosphatase

A phase 2 PK/PD study of andexanet alfa for reversal of rivaroxaban and edoxaban anticoagulation in healthy volunteers

Expression Cloning and Characterization of the C28 Acyltransferase of Lipid A Biosynthesis in Rhizobium leguminosarum

Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amide hydrolase

Interaction of Group IA Phospholipase A2 with Metal Ions and Phospholipid Vesicles Probed with Deuterium Exchange Mass Spectrometry

Heteroarylureas with spirocyclic diamine cores as inhibitors of fatty acid amide hydrolase

MsbA transporter-dependent lipid A 1-dephosphorylation on the periplasmic surface of the inner membrane: topography of francisella novicida LpxE expressed in Escherichia coli

1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase

Heteroaryl urea inhibitors of fatty acid amide hydrolase: Structure–mutagenicity relationships for arylamine metabolites

Enzymatic synthesis of lipid A molecules with four amide-linked acyl chains. LpxA acyltransferases selective for an analog of UDP-N-acetylglucosamine in which an amine replaces the 3"-hydroxyl group

Origin of the 2-amino-2-deoxy-gluconate unit in Rhizobium leguminosarum lipid A. Expression cloning of the outer membrane oxidase LpxQ

MsbA Transporter-dependent Lipid A 1-Dephosphorylation on the Periplasmic Surface of the Inner Membrane

Enzymatic Synthesis of Lipid A Molecules with Four Amide-linked Acyl Chains

Origin of the 2-Amino-2-deoxy-gluconate Unit inRhizobium leguminosarum Lipid A

Purification and Characterization of the Lipid A 1-Phosphatase LpxE of Rhizobium leguminosarumS

Heteroaryl urea inhibitors of fatty acid amide hydrolase: Structureamutagenicity relationships for arylamine metabolites

Interaction of Group IA Phospholipase A 2 with Metal Ions and Phospholipid Vesicles Probed with Deuterium Exchange Mass Spectrometry

Interaction of Group IA Phospholipase A sub(2) with Metal Ions and Phospholipid Vesicles Probed with Deuterium Exchange Mass Spectrometry

Enzymatic Synthesis of Lipid A Molecules with Four Amide-linked Acyl Chains: LpxA Acyltransferases Selective for an Analog of UDP

Heteroarylureas with fused bicyclic diamine cores as inhibitors of fatty acid amide hydrolase

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