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Mapping the Mechanical and Immunological Profiles of Polymeric Microneedles to Enable Vaccine and Immunotherapy Applications

Frontiers in immunology, 2022-03, Vol.13, p.843355-843355

2022

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Genetic Defects in Phosphoinositide 3-Kinase δ Influence CD8 + T Cell Survival, Differentiation, and Function

Frontiers in immunology, 2018-08, Vol.9, p.1758-1758

2018

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The Nanoparticle-Enabled Success of COVID-19 mRNA Vaccines and the Promise of Microneedle Platforms for Pandemic Vaccine Response

DNA and cell biology, 2022-01, Vol.41 (1), p.25-29

Kapnick, Senta M

2022

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Self‐Assembly of Immune Signals to Program Innate Immunity through Rational Adjuvant Design

Advanced science, 2023-01, Vol.10 (1), p.e2202393-n/a

2023

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Engineering metabolism to modulate immunity

Advanced drug delivery reviews, 2024-01, Vol.204, p.115122, Article 115122

2024

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Mitochondrial disease disrupts hepatic allostasis and lowers the threshold for immune-mediated liver toxicity

Molecular metabolism (Germany), 2020-07, Vol.37, p.100981-100981, Article 100981

2020

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The emerging role of immune dysfunction in mitochondrial diseases as a paradigm for understanding immunometabolism

Metabolism, clinical and experimental, 2018-04, Vol.81, p.97-112

2018

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Cytochrome c Oxidase Activity Is a Metabolic Checkpoint that Regulates Cell Fate Decisions During T Cell Activation and Differentiation

Cell metabolism, 2017-06, Vol.25 (6), p.1254-1268.e7

2017

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Cortical actin recovery at the immunological synapse leads to termination of lytic granule secretion in cytotoxic T lymphocytes

Proceedings of the National Academy of Sciences - PNAS, 2017-08, Vol.114 (32), p.E6585-E6594

2017

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Biophysical Properties of Self-Assembled Immune Signals Impact Signal Processing and the Nature of Regulatory Immune Function

Nano letters, 2021-05, Vol.21 (9), p.3762-3771

2021

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Application of Bioluminescence Imaging to the Prediction of Lethality in Vaccinia Virus-Infected Mice

Journal of Virology, 2009-10, Vol.83 (20), p.10437-10447

2009

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Exploiting Rational Assembly to Map Distinct Roles of Regulatory Cues during Autoimmune Therapy

ACS nano, 2021-03, Vol.15 (3), p.4305-4320

2021

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Inducible T Cell Kinase Regulates the Acquisition of Cytolytic Capacity and Degranulation in CD8 + CTLs

The Journal of immunology (1950), 2017-04, Vol.198 (7), p.2699-2711

2017

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Passive Immunotherapies Protect WRvFire and IHD-J-Luc Vaccinia Virus-Infected Mice from Lethality by Reducing Viral Loads in the Upper Respiratory Tract and Internal Organs

Journal of Virology, 2011-09, Vol.85 (17), p.9147-9158

2011

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Discoidin domain receptor 2 regulates neutrophil chemotaxis in 3D collagen matrices

Blood, 2013-02, Vol.121 (9), p.1644-1650

2013

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Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1

Science translational medicine, 2016-01, Vol.8 (321), p.321ra7

2016

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PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory

Cell reports (Cambridge), 2021-10, Vol.37 (2), p.109804-109804, Article 109804

2021

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New tuberculosis drug development: targeting the shikimate pathway

Expert opinion on drug discovery, 2008-05, Vol.3 (5), p.565-577

2008

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Lyophilized tolerogenic polymer particles reverse disease in experimental autoimmune encephalomyelitis while retaining drug properties over time

The Journal of immunology (1950), 2023-05, Vol.210 (1_Supplement), p.249-249.15

2023

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Inducible T cell kinase regulates the acquisition of cytolytic capacity and degranulation in CD8+ cytotoxic T lymphocytes1

The Journal of immunology (1950), 2017-02, Vol.198 (7), p.2699-2711

2017

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PI3Kd coordinates transcriptional, epigenetic and metabolic changes to promote effector CD8 T cells at the expense of memory

The Journal of immunology (1950), 2021-05, Vol.206 (1_Supplement), p.52-52.18

2021

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Dissecting the role of Phosphotidylinositol 3-Kinase (PI3K) δ in the germinal center reaction through a mouse model of hyperactivated Pik3cd

The Journal of immunology (1950), 2017-05, Vol.198 (1_Supplement), p.74-74.11

2017

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A single-dose, tolerizing vaccine induces antigen-specific regulatory T cells and durable remission while preserving healthy immunity in a mouse model of Multiple sclerosis

The Journal of immunology (1950), 2023-05, Vol.210 (1_Supplement), p.165-165.11

2023

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Mapping the Mechanical and Immunological Profiles of Polymeric Microneedles to Enable Vaccine and Immunotherapy Applications

Genetic Defects in Phosphoinositide 3-Kinase δ Influence CD8 + T Cell Survival, Differentiation, and Function

The Nanoparticle-Enabled Success of COVID-19 mRNA Vaccines and the Promise of Microneedle Platforms for Pandemic Vaccine Response

Self‐Assembly of Immune Signals to Program Innate Immunity through Rational Adjuvant Design

Engineering metabolism to modulate immunity

Mitochondrial disease disrupts hepatic allostasis and lowers the threshold for immune-mediated liver toxicity

The emerging role of immune dysfunction in mitochondrial diseases as a paradigm for understanding immunometabolism

Cytochrome c Oxidase Activity Is a Metabolic Checkpoint that Regulates Cell Fate Decisions During T Cell Activation and Differentiation

Cortical actin recovery at the immunological synapse leads to termination of lytic granule secretion in cytotoxic T lymphocytes

Biophysical Properties of Self-Assembled Immune Signals Impact Signal Processing and the Nature of Regulatory Immune Function

Application of Bioluminescence Imaging to the Prediction of Lethality in Vaccinia Virus-Infected Mice

Exploiting Rational Assembly to Map Distinct Roles of Regulatory Cues during Autoimmune Therapy

Inducible T Cell Kinase Regulates the Acquisition of Cytolytic Capacity and Degranulation in CD8 + CTLs

Passive Immunotherapies Protect WRvFire and IHD-J-Luc Vaccinia Virus-Infected Mice from Lethality by Reducing Viral Loads in the Upper Respiratory Tract and Internal Organs

Discoidin domain receptor 2 regulates neutrophil chemotaxis in 3D collagen matrices

Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1

PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory

New tuberculosis drug development: targeting the shikimate pathway

Lyophilized tolerogenic polymer particles reverse disease in experimental autoimmune encephalomyelitis while retaining drug properties over time

Inducible T cell kinase regulates the acquisition of cytolytic capacity and degranulation in CD8+ cytotoxic T lymphocytes1

PI3Kd coordinates transcriptional, epigenetic and metabolic changes to promote effector CD8 T cells at the expense of memory

Dissecting the role of Phosphotidylinositol 3-Kinase (PI3K) δ in the germinal center reaction through a mouse model of hyperactivated Pik3cd

A single-dose, tolerizing vaccine induces antigen-specific regulatory T cells and durable remission while preserving healthy immunity in a mouse model of Multiple sclerosis

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