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Preferential binding to dopamine D3 over D2 receptors by cariprazine in patients with schizophrenia using PET with the D3/D2 receptor ligand [11C]-(+)-PHNO

Psychopharmacology, 2016-10, Vol.233 (19-20), p.3503-3512

2016

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Comment on: “Clinical Pharmacokinetics of Atypical Antipsychotics: An Update”

Clinical pharmacokinetics, 2019-09, Vol.58 (9), p.1215-1216

2019

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Population Pharmacokinetics of Cariprazine and its Major Metabolites

European journal of drug metabolism and pharmacokinetics, 2021-01, Vol.46 (1), p.53-69

2021

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Clinical pharmacology study of cariprazine (MP-214) in patients with schizophrenia (12-week treatment)

Drug design, development and therapy, 2016-01, Vol.10 (Issue 1), p.327-338

2016

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Role of sodium channel inhibition in neuroprotection: effect of vinpocetine

Brain Research Bulletin, 2000-10, Vol.53 (3), p.245-254

2000

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Cariprazine (RGH-188), a potent D 3/D 2 dopamine receptor partial agonist, binds to dopamine D 3 receptors in vivo and shows antipsychotic-like and procognitive effects in rodents

Neurochemistry international, 2011-11, Vol.59 (6), p.925-935

2011

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Cariprazine (RGH-188), a potent D3/D2 dopamine receptor partial agonist, binds to dopamine D3 receptors in vivo and shows antipsychotic-like and procognitive effects in rodents

Neurochemistry international, 2011-11, Vol.59 (6), p.925-935

2011

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Relationship Between Plasma Concentrations and Clinical Effects of Cariprazine in Patients With Schizophrenia or Bipolar Mania

Clinical and translational science, 2020-03, Vol.13 (2), p.362-371

2020

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Sensitive LC–MS/MS methods for the quantification of RGH-188 and its active metabolites, desmethyl- and didesmethyl-RGH-188 in human plasma and urine

Journal of pharmaceutical and biomedical analysis, 2008-09, Vol.48 (2), p.388-397

2008

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Preferential binding to dopamine D.sub.3 over D.sub.2 receptors by cariprazine in patients with schizophrenia using PET with the D.sub.3/D.sub.2 receptor ligand [.sup.11C]--PHNO

Psychopharmacology, 2016-10, p.3503

2016

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Preferential binding to dopamine D sub(3) over D sub(2) receptors by cariprazine in patients with schizophrenia using PET with the D sub(3)/D sub(2) receptor ligand [ super(11)C]-(+)-PHNO

Psychopharmacology, 2016-10, Vol.233 (19-20), p.3503-3512

2016

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Effects of RGH-237 [ N -{4-[4-(3-Aminocarbonyl-phenyl)-piperazin-1-yl]-butyl}-4-bromo-benzamide], an Orally Active, Selective Dopamine D 3 Receptor Partial Agonist in Animal Models of Cocaine Abuse

The Journal of pharmacology and experimental therapeutics, 2007-03, Vol.320 (3), p.1268-1278

2007

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Clinical pharmacology study of cariprazine

Drug design, development and therapy, 2016-01, Vol.10, p.327

2016

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Physico-chemical characterization of a novel group of dopamine D3/D2 receptor ligands, potential atypical antipsychotic agents

Journal of pharmaceutical and biomedical analysis, 2008-11, Vol.48 (3), p.678-684

2008

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Physico-chemical characterization of a novel group of dopamine D 3/D 2 receptor ligands, potential atypical antipsychotic agents

Journal of pharmaceutical and biomedical analysis, 2008-11, Vol.48 (3), p.678-684

2008

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Discovery of cariprazine (RGH-188): A novel antipsychotic acting on dopamine D3/D2 receptors

Bioorganic & medicinal chemistry letters, 2012-05, Vol.22 (10), p.3437-3440

2012

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Comment on: "Clinical Pharmacokinetics of Atypical Antipsychotics: An Update"/Reply

Clinical pharmacokinetics, 2019-09, Vol.58 (9), p.1215-1218

2019

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Physico-chemical characterization of a novel group of dopamine D sub(3)/D sub(2) receptor ligands, potential atypical antipsychotic agents

Journal of pharmaceutical and biomedical analysis, 2008-11, Vol.48 (3), p.678-684

2008

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An HPLC/UV method for the determination of RGH-1756 in dog and rat plasma

Journal of pharmaceutical and biomedical analysis, 2001-03, Vol.24 (5), p.913-920

2001

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Preferential binding to dopamine D^sub 3^ over D^sub 2^ receptors by cariprazine in patients with schizophrenia using PET with the D^sub 3^/D^sub 2^ receptor ligand [^sup 11^C]-(+)-PHNO

Psychopharmacology, 2016-10, Vol.233 (19-20), p.3503

2016

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Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: II. behavioural characterisation of RG-15

Naunyn-Schmiedeberg's archives of pharmacology, 2008-11, Vol.378 (5), p.529-539

2008

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Physico-chemical characterization of a novel group of dopamine D(3)/D(2) receptor ligands, potential atypical antipsychotic agents

Journal of pharmaceutical and biomedical analysis, 2008-11, Vol.48 (3), p.678-684

2008

Volltextzugriff (PDF)

Effects of RGH-237 [N-{4-[4-(3-aminocarbonyl-phenyl)-piperazin-1-yl]-butyl}-4-bromo-benzamide], an orally active, selective dopamine D(3) receptor partial agonist in animal models of cocaine abuse

The Journal of pharmacology and experimental therapeutics, 2007-03, Vol.320 (3), p.1268

2007

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High-performance liquid chromatographic method for the determination of RGH-5002 in human, rabbit and rat plasma

Journal of pharmaceutical and biomedical analysis, 1996-06, Vol.14 (8), p.1233-1239

1996

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A rapid capillary gas chromatographic method for the determination of diazepam in human plasma and saliva

Acta pharmaceutica Hungarica, 1982-11, Vol.52 (6), p.246

1982

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Preferential binding to dopamine D3 over D2 receptors by cariprazine in patients with schizophrenia using PET with the D3/D2 receptor ligand [11C]-(+)-PHNO

Comment on: “Clinical Pharmacokinetics of Atypical Antipsychotics: An Update”

Population Pharmacokinetics of Cariprazine and its Major Metabolites

Clinical pharmacology study of cariprazine (MP-214) in patients with schizophrenia (12-week treatment)

Role of sodium channel inhibition in neuroprotection: effect of vinpocetine

Cariprazine (RGH-188), a potent D 3/D 2 dopamine receptor partial agonist, binds to dopamine D 3 receptors in vivo and shows antipsychotic-like and procognitive effects in rodents

Cariprazine (RGH-188), a potent D3/D2 dopamine receptor partial agonist, binds to dopamine D3 receptors in vivo and shows antipsychotic-like and procognitive effects in rodents

Relationship Between Plasma Concentrations and Clinical Effects of Cariprazine in Patients With Schizophrenia or Bipolar Mania

Sensitive LC–MS/MS methods for the quantification of RGH-188 and its active metabolites, desmethyl- and didesmethyl-RGH-188 in human plasma and urine

Preferential binding to dopamine D.sub.3 over D.sub.2 receptors by cariprazine in patients with schizophrenia using PET with the D.sub.3/D.sub.2 receptor ligand [.sup.11C]--PHNO

Preferential binding to dopamine D sub(3) over D sub(2) receptors by cariprazine in patients with schizophrenia using PET with the D sub(3)/D sub(2) receptor ligand [ super(11)C]-(+)-PHNO

Effects of RGH-237 [ N -{4-[4-(3-Aminocarbonyl-phenyl)-piperazin-1-yl]-butyl}-4-bromo-benzamide], an Orally Active, Selective Dopamine D 3 Receptor Partial Agonist in Animal Models of Cocaine Abuse

Clinical pharmacology study of cariprazine

Physico-chemical characterization of a novel group of dopamine D3/D2 receptor ligands, potential atypical antipsychotic agents

Physico-chemical characterization of a novel group of dopamine D 3/D 2 receptor ligands, potential atypical antipsychotic agents

Discovery of cariprazine (RGH-188): A novel antipsychotic acting on dopamine D3/D2 receptors

Comment on: "Clinical Pharmacokinetics of Atypical Antipsychotics: An Update"/Reply

Physico-chemical characterization of a novel group of dopamine D sub(3)/D sub(2) receptor ligands, potential atypical antipsychotic agents

An HPLC/UV method for the determination of RGH-1756 in dog and rat plasma

Preferential binding to dopamine D^sub 3^ over D^sub 2^ receptors by cariprazine in patients with schizophrenia using PET with the D^sub 3^/D^sub 2^ receptor ligand [^sup 11^C]-(+)-PHNO

Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: II. behavioural characterisation of RG-15

Physico-chemical characterization of a novel group of dopamine D(3)/D(2) receptor ligands, potential atypical antipsychotic agents

Effects of RGH-237 [N-{4-[4-(3-aminocarbonyl-phenyl)-piperazin-1-yl]-butyl}-4-bromo-benzamide], an orally active, selective dopamine D(3) receptor partial agonist in animal models of cocaine abuse

High-performance liquid chromatographic method for the determination of RGH-5002 in human, rabbit and rat plasma

A rapid capillary gas chromatographic method for the determination of diazepam in human plasma and saliva

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