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Wirkstofffindung in kardiovaskulären und metabolischen Erkrankungen

Biospektrum, 2017-10, Vol.23 (6), p.720-720

Kannt, Aimo

2017

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Short-term variability of the human serum metabolome depending on nutritional and metabolic health status

Scientific reports, 2020-10, Vol.10 (1), p.16310-16310, Article 16310

2020

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The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2

Stem cell reports, 2022-02, Vol.17 (2), p.307-320

2022

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Characterization of Glycolytic Enzymes and Pyruvate Kinase M2 in Type 1 and 2 Diabetic Nephropathy

Diabetes care, 2019-07, Vol.42 (7), p.1263-1273

2019

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Sarcopenia: An Undiagnosed Condition in Older Adults. Current Consensus Definition: Prevalence, Etiology, and Consequences. International Working Group on Sarcopenia

Journal of the American Medical Directors Association, 2011, Vol.12 (4), p.249-256

2011

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Novel Inhibitors of Nicotinamide- N -Methyltransferase for the Treatment of Metabolic Disorders

Molecules (Basel, Switzerland), 2021-02, Vol.26 (4), p.991

2021

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Effects of Whole-Body Adenylyl Cyclase 5 ( Adcy5 ) Deficiency on Systemic Insulin Sensitivity and Adipose Tissue

International journal of molecular sciences, 2021-04, Vol.22 (9), p.4353

2021

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Ibuprofen, Flurbiprofen, Etoricoxib or Paracetamol Do Not Influence ACE2 Expression and Activity In Vitro or in Mice and Do Not Exacerbate In-Vitro SARS-CoV-2 Infection

International journal of molecular sciences, 2022-01, Vol.23 (3), p.1049

2022

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Association Between Serum Carnosinase Concentration and Activity and Renal Function Impairment in a Type-2 Diabetes Cohort

Frontiers in pharmacology, 2022-07, Vol.13, p.899057-899057

2022

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Running on mixed fuel‐dual agonistic approach of GLP‐1 and GCG receptors leads to beneficial impact on body weight and blood glucose control: A comparative study between mice and non‐human primates

Diabetes, obesity & metabolism, 2018-08, Vol.20 (8), p.1836-1851

2018

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Team Players or Opponents: Coadministration of Selective Glucagon and GLP-1 Receptor Agonists in Obese Diabetic Monkeys

Endocrinology (Philadelphia), 2018-08, Vol.159 (8), p.3105-3119

2018

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Smoking and Other Risk Factors in Type 2 Diabetes

The New England journal of medicine, 2018-12, Vol.379 (26), p.2574

Kannt, Aimo

2018

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Expanding the arsenal of E3 ubiquitin ligases for proximity-induced protein degradation

Cell chemical biology, 2021-07, Vol.28 (7), p.1014-1031

2021

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Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase

Bioorganic & medicinal chemistry letters, 2018-03, Vol.28 (5), p.922-925

2018

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Neutralizing IL-38 activates γδ T cell-dependent antitumor immunity and sensitizes for chemotherapy

Journal for immunotherapy of cancer, 2024-08, Vol.12 (8), p.e008641

2024

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Analysis of 16 studies in nine rodent models does not support the hypothesis that diabetic polyuria is a main reason of urinary bladder enlargement

Frontiers in physiology, 2022-08, Vol.13, p.923555-923555

2022

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A Therapeutic Silencing RNA Targeting Hepatocyte TAZ Prevents and Reverses Fibrosis in Nonalcoholic Steatohepatitis in Mice

Hepatology communications, 2019-09, Vol.3 (9), p.1221-1234

2019

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Systemic treatment with erythropoietin protects the neurovascular unit in a rat model of retinal neurodegeneration

PloS one, 2014-07, Vol.9 (7), p.e102013

2014

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GPR17 gene disruption does not alter food intake or glucose homeostasis in mice

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (6), p.1845-1849

2015

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Pharmacological Characterization of SAR407899, a Novel Rho-Kinase Inhibitor

Hypertension (Dallas, Tex. 1979), 2009-09, Vol.54 (3), p.676-683

2009

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Managing risks in drug discovery: reproducibility of published findings

Naunyn - Schmiedeberg's Archives of Pharmacology, 2016-04, Vol.389 (4), p.353-360

2016

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Wirkstofffindung in kardiovaskulären und metabolischen Erkrankungen

Short-term variability of the human serum metabolome depending on nutritional and metabolic health status

Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction

The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2

Characterization of Glycolytic Enzymes and Pyruvate Kinase M2 in Type 1 and 2 Diabetic Nephropathy

Sarcopenia: An Undiagnosed Condition in Older Adults. Current Consensus Definition: Prevalence, Etiology, and Consequences. International Working Group on Sarcopenia

Novel Inhibitors of Nicotinamide- N -Methyltransferase for the Treatment of Metabolic Disorders

A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders

Effects of Whole-Body Adenylyl Cyclase 5 ( Adcy5 ) Deficiency on Systemic Insulin Sensitivity and Adipose Tissue

Ibuprofen, Flurbiprofen, Etoricoxib or Paracetamol Do Not Influence ACE2 Expression and Activity In Vitro or in Mice and Do Not Exacerbate In-Vitro SARS-CoV-2 Infection

Association Between Serum Carnosinase Concentration and Activity and Renal Function Impairment in a Type-2 Diabetes Cohort

Running on mixed fuel‐dual agonistic approach of GLP‐1 and GCG receptors leads to beneficial impact on body weight and blood glucose control: A comparative study between mice and non‐human primates

Team Players or Opponents: Coadministration of Selective Glucagon and GLP-1 Receptor Agonists in Obese Diabetic Monkeys

Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders

Smoking and Other Risk Factors in Type 2 Diabetes

Expanding the arsenal of E3 ubiquitin ligases for proximity-induced protein degradation

Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase

Neutralizing IL-38 activates γδ T cell-dependent antitumor immunity and sensitizes for chemotherapy

Nutrigenetic Interactions Might Modulate the Antioxidant and Anti-Inflammatory Status in Mastiha-Supplemented Patients With NAFLD

Analysis of 16 studies in nine rodent models does not support the hypothesis that diabetic polyuria is a main reason of urinary bladder enlargement

A Therapeutic Silencing RNA Targeting Hepatocyte TAZ Prevents and Reverses Fibrosis in Nonalcoholic Steatohepatitis in Mice

Systemic treatment with erythropoietin protects the neurovascular unit in a rat model of retinal neurodegeneration

GPR17 gene disruption does not alter food intake or glucose homeostasis in mice

Pharmacological Characterization of SAR407899, a Novel Rho-Kinase Inhibitor

Managing risks in drug discovery: reproducibility of published findings

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