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Pharmacogenomics of gemcitabine: can genetic studies lead to tailor-made therapy?

British journal of cancer, 2007-07, Vol.97 (2), p.145-151

2007

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A whole-genome association study of major determinants for allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients

The pharmacogenomics journal, 2013-02, Vol.13 (1), p.60-69

2013

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Racial variability in haplotype frequencies of UGT1A1 and glucuronidation activity of a novel single nucleotide polymorphism 686C> T (P229L) found in an African-American

Drug metabolism and disposition, 2005-03, Vol.33 (3), p.458-465

2005

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Homozygous CDA3 is a major cause of life-threatening toxicities in gemcitabine-treated Japanese cancer patients

British journal of cancer, 2009-03, Vol.100 (6), p.870-873

2009

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Haplotype structures of the UGT1A gene complex in a Japanese population

The pharmacogenomics journal, 2006-01, Vol.6 (1), p.63-75

2006

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Pharmacogenomics of severe cutaneous adverse reactions and drug-induced liver injury

Journal of human genetics, 2013-06, Vol.58 (6), p.317-326

2013

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Liquid chromatographic–atmospheric pressure chemical ionization mass spectrometric analysis of opiates and metabolites in rat urine after inhalation of opium

Journal of chromatography. B, 2003-06, Vol.789 (1), p.139-150

2003

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A new statistical screening approach for finding pharmacokinetics-related genes in genome-wide studies

The pharmacogenomics journal, 2009-04, Vol.9 (2), p.137-146

2009

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Vertical Integration of Pharmacogenetics in Population PK/PD Modeling: A Novel Information Theoretic Method

CPT: pharmacometrics and systems pharmacology, 2013-02, Vol.2 (2), p.1-10

2013

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HLA-B locus in Japanese patients with anti-epileptics and allopurinol-related Stevens-–Johnson syndrome and toxic epidermal necrolysis

Pharmacogenomics, 2008-11, Vol.9 (11), p.1617-1622

2008

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Genetic Variations and Haplotype Structures of the ABCB1 Gene in a Japanese Population: An Expanded Haplotype Block Covering the Distal Promoter Region, and Associated Ethnic Differences

Annals of human genetics, 2006-09, Vol.70 (5), p.605-622

2006

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Hydrodynamic Flows Around Tablets in Different Pharmacopeial Dissolution Tests

Drug development and industrial pharmacy, 2002-01, Vol.28 (6), p.655-662

2002

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UGT1A1 Haplotypes Associated with Reduced Glucuronidation and Increased Serum Bilirubin in Irinotecan‐administered Japanese Patients with Cancer

Clinical pharmacology and therapeutics, 2004-06, Vol.75 (6), p.501-515

2004

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Prediction of Severe Adverse Drug Reactions Using Pharmacogenetic Biomarkers

DRUG METABOLISM AND PHARMACOKINETICS, 2010-01, Vol.25 (2), p.122-133

2010

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Functional characterization of human UDP-glucuronosyltransferase 1A9 variant, D256N, found in Japanese cancer patients

The Journal of pharmacology and experimental therapeutics, 2003-08, Vol.306 (2), p.688-693

2003

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508 POSTER Association of genetic polymorphisms with survival in Japanese pancreatic cancer patients treated with gemcitabine

European journal of cancer supplements, 2007, Vol.5 (4), p.92-92

2007

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Effect of cytidine deaminase (CDA)–related biomarkers on overall survival in patients with advanced pancreatic cancer receiving gemcitabine (GEM) monotherapy

Journal of clinical oncology, 2011-05, Vol.29 (15_suppl), p.e14645-e14645

2011

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Impact of the haplotype CYP3A416B harboring the Thr185Ser substitution on paclitaxel metabolism in Japanese patients with cancer

Clinical pharmacology and therapeutics, 2006-08, Vol.80 (2), p.179-191

2006

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Collaborative study on the development of a standard for evaluation of vibration levels for dissolution apparatus

International journal of pharmaceutics, 1998-11, Vol.175 (1), p.119-129

1998

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Assessment of Gastric Acidity of Japanese Subjects over the Last 15 Years

Biological and Pharmaceutical Bulletin, 2001, Vol.24(3), pp.313-315

2001

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Comprehensive UGT1A1 genotyping in a Japanese population by pyrosequencing

Clinical chemistry (Baltimore, Md.), 2003-07, Vol.49 (7), p.1182-1185

2003

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Haplotype structures of EPHX1 and their effects on the metabolism of carbamazepine-10,11-epoxide in Japanese epileptic patients

European journal of clinical pharmacology, 2005-03, Vol.61 (1), p.25-34

2005

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Association of SNPs in ABCC1 gene with overall survival in stage IV pancreatic adenocarcinoma patients treated with gemcitabine monotherapy

Journal of clinical oncology, 2008-05, Vol.26 (15_suppl), p.14504-14504

2008

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A new metabolite of irinotecan in which formation is mediated by human hepatic cytochrome P-450 3A4

Drug metabolism and disposition, 2001-11, Vol.29 (11), p.1505

2001

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Association of a novel polymorphism G-133C of thymidylate synthase (TYMS) gene with 5-FU-related severe diarrhea in Japanese patients with colorectal cancer

Journal of clinical oncology, 2007-06, Vol.25 (18_suppl), p.14108-14108

2007

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Pharmacogenomics of gemcitabine: can genetic studies lead to tailor-made therapy?

A whole-genome association study of major determinants for allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients

Racial variability in haplotype frequencies of UGT1A1 and glucuronidation activity of a novel single nucleotide polymorphism 686C> T (P229L) found in an African-American

Homozygous CDA3 is a major cause of life-threatening toxicities in gemcitabine-treated Japanese cancer patients

Haplotype structures of the UGT1A gene complex in a Japanese population

Pharmacogenomics of severe cutaneous adverse reactions and drug-induced liver injury

Liquid chromatographic–atmospheric pressure chemical ionization mass spectrometric analysis of opiates and metabolites in rat urine after inhalation of opium

A new statistical screening approach for finding pharmacokinetics-related genes in genome-wide studies

Vertical Integration of Pharmacogenetics in Population PK/PD Modeling: A Novel Information Theoretic Method

HLA-B locus in Japanese patients with anti-epileptics and allopurinol-related Stevens-–Johnson syndrome and toxic epidermal necrolysis

Genetic Variations and Haplotype Structures of the ABCB1 Gene in a Japanese Population: An Expanded Haplotype Block Covering the Distal Promoter Region, and Associated Ethnic Differences

Hydrodynamic Flows Around Tablets in Different Pharmacopeial Dissolution Tests

UGT1A1 Haplotypes Associated with Reduced Glucuronidation and Increased Serum Bilirubin in Irinotecan‐administered Japanese Patients with Cancer

Prediction of Severe Adverse Drug Reactions Using Pharmacogenetic Biomarkers

Functional characterization of human UDP-glucuronosyltransferase 1A9 variant, D256N, found in Japanese cancer patients

508 POSTER Association of genetic polymorphisms with survival in Japanese pancreatic cancer patients treated with gemcitabine

Effect of cytidine deaminase (CDA)–related biomarkers on overall survival in patients with advanced pancreatic cancer receiving gemcitabine (GEM) monotherapy

Impact of the haplotype CYP3A416B harboring the Thr185Ser substitution on paclitaxel metabolism in Japanese patients with cancer

Collaborative study on the development of a standard for evaluation of vibration levels for dissolution apparatus

Assessment of Gastric Acidity of Japanese Subjects over the Last 15 Years

Comprehensive UGT1A1 genotyping in a Japanese population by pyrosequencing

Haplotype structures of EPHX1 and their effects on the metabolism of carbamazepine-10,11-epoxide in Japanese epileptic patients

Association of SNPs in ABCC1 gene with overall survival in stage IV pancreatic adenocarcinoma patients treated with gemcitabine monotherapy

A new metabolite of irinotecan in which formation is mediated by human hepatic cytochrome P-450 3A4

Association of a novel polymorphism G-133C of thymidylate synthase (TYMS) gene with 5-FU-related severe diarrhea in Japanese patients with colorectal cancer

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