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Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapy

Molecular cancer, 2021-01, Vol.20 (1), p.15-15, Article 15

2021

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Targeting CDK12 for Cancer Therapy: Function, Mechanism, and Drug Discovery

Cancer research (Chicago, Ill.), 2021-01, Vol.81 (1), p.18-26

2021

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Unraveling the complexity of STAT3 in cancer: molecular understanding and drug discovery

Journal of experimental & clinical cancer research, 2024-01, Vol.43 (1), p.23-23, Article 23

2024

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EPRS/GluRS promotes gastric cancer development via WNT/GSK-3β/β-catenin signaling pathway

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2021-09, Vol.24 (5), p.1021-1036

2021

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SDCBP/MDA-9/syntenin phosphorylation by AURKA promotes esophageal squamous cell carcinoma progression through the EGFR-PI3K-Akt signaling pathway

Oncogene, 2020-07, Vol.39 (31), p.5405-5419

2020

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Uncovering the microbiota in renal cell carcinoma tissue using 16S rRNA gene sequencing

Journal of cancer research and clinical oncology, 2021-02, Vol.147 (2), p.481-491

2021

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The Role of p21-Activated Kinases in Cancer and Beyond: Where Are We Heading?

Frontiers in cell and developmental biology, 2021-03, Vol.9, p.641381-641381

2021

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Targeting CRAF kinase in anti-cancer therapy: progress and opportunities

Molecular cancer, 2023-12, Vol.22 (1), p.208-208, Article 208

2023

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Knockdown of Pyruvate Kinase M Inhibits Cell Growth and Migration by Reducing NF-kB Activity in Triple-Negative Breast Cancer Cells

Molecules and Cells, 2019, 42(9), , pp.628-636

2019

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Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma In Vitro and Patient-Derived Xenografts In Vivo

Molecular cancer therapeutics, 2018-07, Vol.17 (7), p.1540-1553

2018

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CDK15 promotes colorectal cancer progression via phosphorylating PAK4 and regulating β-catenin/ MEK-ERK signaling pathway

Cell death and differentiation, 2022-01, Vol.29 (1), p.14-27

2022

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Spatial transcriptomics analysis of esophageal squamous precancerous lesions and their progression to esophageal cancer

Nature communications, 2023-08, Vol.14 (1), p.4779-4779, Article 4779

2023

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Ubiquitination of ADRα1d/SerpinA1 complex stimulates hypoxia to induce gastric tumorigenesis with a combination of Helicobacter pylori and chronic stress through IL-1α

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2022-07, Vol.25 (4), p.726-740

2022

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Mutations found in cancer patients compromise DNA binding of the winged helix protein STK19

Scientific reports, 2024-06, Vol.14 (1), p.14098-10

2024

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BRD4 drives esophageal squamous cell carcinoma growth by promoting RCC2 expression

Oncogene, 2022-01, Vol.41 (3), p.347-360

2022

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Cancer/testis antigens: promising immunotherapy targets for digestive tract cancers

Frontiers in immunology, 2023-06, Vol.14, p.1190883-1190883

2023

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Integrated metabolomic and transcriptomic analyses of Dendrobium chrysotoxum and D. thyrsiflorum reveal the biosynthetic pathway from gigantol to erianin

Frontiers in plant science, 2024-09, Vol.15, p.1436560

2024

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Targeted therapy of the AKT kinase inhibits esophageal squamous cell carcinoma growth in vitro and in vivo

International journal of cancer, 2019-08, Vol.145 (4), p.1007-1019

2019

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Periplogenin suppresses the growth of esophageal squamous cell carcinoma in vitro and in vivo by targeting STAT3

Oncogene, 2021-06, Vol.40 (23), p.3942-3958

2021

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MiRNA-363-3p/DUSP10/JNK axis mediates chemoresistance by enhancing DNA damage repair in diffuse large B-cell lymphoma

Leukemia, 2022-07, Vol.36 (7), p.1861-1869

2022

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Cytokine Signature Induced by SARS-CoV-2 Spike Protein in a Mouse Model

Frontiers in immunology, 2021-01, Vol.11, p.621441

2021

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Costunolide is a dual inhibitor of MEK1 and AKT1/2 that overcomes osimertinib resistance in lung cancer

Molecular cancer, 2022-10, Vol.21 (1), p.1-193, Article 193

2022

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Oxethazaine inhibits esophageal squamous cell carcinoma proliferation and metastasis by targeting aurora kinase A

Cell death & disease, 2022-02, Vol.13 (2), p.189-189, Article 189

2022

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Cirsiliol targets tyrosine kinase 2 to inhibit esophageal squamous cell carcinoma growth in vitro and in vivo

Journal of experimental & clinical cancer research, 2021-03, Vol.40 (1), p.105-105, Article 105

2021

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Nuplazid suppresses esophageal squamous cell carcinoma growth in vitro and in vivo by targeting PAK4

British journal of cancer, 2022-04, Vol.126 (7), p.1037-1046

2022

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Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapy

Targeting CDK12 for Cancer Therapy: Function, Mechanism, and Drug Discovery

Unraveling the complexity of STAT3 in cancer: molecular understanding and drug discovery

EPRS/GluRS promotes gastric cancer development via WNT/GSK-3β/β-catenin signaling pathway

SDCBP/MDA-9/syntenin phosphorylation by AURKA promotes esophageal squamous cell carcinoma progression through the EGFR-PI3K-Akt signaling pathway

Uncovering the microbiota in renal cell carcinoma tissue using 16S rRNA gene sequencing

The Role of p21-Activated Kinases in Cancer and Beyond: Where Are We Heading?

Targeting CRAF kinase in anti-cancer therapy: progress and opportunities

Knockdown of Pyruvate Kinase M Inhibits Cell Growth and Migration by Reducing NF-kB Activity in Triple-Negative Breast Cancer Cells

Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma In Vitro and Patient-Derived Xenografts In Vivo

CDK15 promotes colorectal cancer progression via phosphorylating PAK4 and regulating β-catenin/ MEK-ERK signaling pathway

Spatial transcriptomics analysis of esophageal squamous precancerous lesions and their progression to esophageal cancer

Ubiquitination of ADRα1d/SerpinA1 complex stimulates hypoxia to induce gastric tumorigenesis with a combination of Helicobacter pylori and chronic stress through IL-1α

Mutations found in cancer patients compromise DNA binding of the winged helix protein STK19

BRD4 drives esophageal squamous cell carcinoma growth by promoting RCC2 expression

Cancer/testis antigens: promising immunotherapy targets for digestive tract cancers

Integrated metabolomic and transcriptomic analyses of Dendrobium chrysotoxum and D. thyrsiflorum reveal the biosynthetic pathway from gigantol to erianin

Targeted therapy of the AKT kinase inhibits esophageal squamous cell carcinoma growth in vitro and in vivo

Periplogenin suppresses the growth of esophageal squamous cell carcinoma in vitro and in vivo by targeting STAT3

MiRNA-363-3p/DUSP10/JNK axis mediates chemoresistance by enhancing DNA damage repair in diffuse large B-cell lymphoma

Cytokine Signature Induced by SARS-CoV-2 Spike Protein in a Mouse Model

Costunolide is a dual inhibitor of MEK1 and AKT1/2 that overcomes osimertinib resistance in lung cancer

Oxethazaine inhibits esophageal squamous cell carcinoma proliferation and metastasis by targeting aurora kinase A

Cirsiliol targets tyrosine kinase 2 to inhibit esophageal squamous cell carcinoma growth in vitro and in vivo

Nuplazid suppresses esophageal squamous cell carcinoma growth in vitro and in vivo by targeting PAK4

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