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AmBisome: relationship between the pharmacokinetic characteristics acquired by liposomal formulation and safety/efficacy

Journal of liposome research, 2017-07, Vol.27 (3), p.186-194

2017

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Novel Carbapenem Antibiotics for Parenteral and Oral Applications: In Vitro and In Vivo Activities of 2-Aryl Carbapenems and Their Pharmacokinetics in Laboratory Animals

Antimicrobial Agents and Chemotherapy, 2013-02, Vol.57 (2), p.697-707

2013

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Comparative study of the efficacy of liposomal amphotericin B and amphotericin B deoxycholate against six species of Zygomycetes in a murine lethal infection model

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2010-12, Vol.16 (6), p.388-395

2010

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Pharmacodynamics of SMP-601 (PTZ601) against Vancomycin-Resistant Enterococcus faecium and Methicillin-Resistant Staphylococcus aureus in Neutropenic Murine Thigh Infection Models

Antimicrobial Agents and Chemotherapy, 2009-08, Vol.53 (8), p.3391-3398

2009

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Therapeutic effect of meropenem on an experimental guinea pig model of meningitis with type b β-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2013-08, Vol.19 (4), p.593-598

2013

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Experimental verification of the efficacy of optimized two-step infusion therapy with meropenem using an in vitro pharmacodynamic model and Monte Carlo simulation

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2010-02, Vol.16 (1), p.1-9

2010

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In Vitro and In Vivo Antibacterial Activities of SM-216601, a New Broad-Spectrum Parenteral Carbapenem

Antimicrobial Agents and Chemotherapy, 2005-10, Vol.49 (10), p.4185-4196

2005

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The Mode of Action of 2-(Thiazol-2-ylthio)-1β-methylcarbapenems against Pseudomonas aeruginosa: The Impact of Outer Membrane Permeability and the Contribution of MexAB-OprM Efflux System

Journal of antibiotics, 2007-02, Vol.60 (2), p.129-135

2007

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BACTERICIAL ACTIVITY OF CHLORHEXIDINE GLUCONATE AGAINST RECENT CLINICAL ISOLATES OF VARIOUS BACTERIAL SPECIES IN JAPAN

The Japanese Journal of Antibiotics, 2004/10/25, Vol.57(5), pp.449-464

2004

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Orally active carbapenem antibiotics I. Antibacterial and pharmacokinetic potential of 2-phenyl and 2-thienylcarbapenems

Journal of antibiotics, 2005-12, Vol.58 (12), p.787-803

2005

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Influence of Fungicidal Activity against Candida tropicalis on the Efficacy of Micafungin and Liposomal Amphotericin B in a Neutropenic Murine Lethal Infection Model

Pharmacology, 2012-01, Vol.90 (3-4), p.133-145

2012

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NDV-3ワクチンは，MRSA感染症の発症・重症化を克服し得るか

ファルマシア, 2015, Vol.51(12), pp.1184-1184

金澤, 勝則

2015

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Therapeutic effect of meropenem on an experimental guinea pig model of meningitis with type b I2-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2013-08, Vol.19 (4), p.593-598

2013

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Structure-activity relationships of carbapenems to the antagonism of the antipseudomonal activity of other β-lactam agents and to the β-lactamase inducibility in Pseudomonas aeruginosa : Effects of 1β-methyl group and C-2 side chain

Journal of antibiotics, 1999-02, Vol.52 (2), p.142-149

1999

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Structure-activity relationships of carbapenems to the antagonism of the antipseudomonal activity of other beta-lactam agents and to the beta-lactamase inducibility in Pseudomonas aeruginosa: effects of 1beta-methyl group and C-2 side chain

Journal of antibiotics, 1999, Vol.52 (2), p.142-149

1999

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Comparative Study on the Efficacy of Liposomal Amphotericin B and Voriconazole in a Murine Pulmonary Aspergillosis Model

Chemotherapy (Basel), 2009-02, Vol.55 (2), p.105-113, Article 105

2009

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In vivo activity of liposomal amphotericin B against Exophiala dermatitidis in a murine lethal infection model

Japanese journal of antibiotics, 2010-06, Vol.63 (3), p.265-272

2010

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IN VITRO COMBINED EFFECT OF MEROPENEM AND VARIOUS ANTIMICROBIAL AGENTS AGAINST β-LACTAMASE-NONPRODUCING AMPICILLIN-RESISTANT Haemophilus influenzae AND PENICILLIN-RESISTANT Streptococcus pneumoniae

The Japanese Journal of Antibiotics, 2005/04/25, Vol.58(2), pp.168-178

2005

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In vitro combined effect of meropenem and various antimicrobial agents against beta-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae and penicillin-resistant Streptococcus pneumoniae

Japanese journal of antibiotics, 2005-04, Vol.58 (2), p.168

2005

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The Mode of Action of 2-(Thiazol-2-ylthio)-1[beta]-methylcarbapenems against Pseudomonas aeruginosa: The Impact of Outer Membrane Permeability and the Contribution of MexAB-OprM Efflux System

Journal of antibiotics, 2007-02, Vol.60 (2), p.129

2007

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The mode of action of 2-(thiazol-2-ylthio)-1beta-methylcarbapenems against Pseudomonas aeruginosa: the impact of outer membrane permeability and the contribution of MexAB-OprM efflux system

Journal of antibiotics, 2007-02, Vol.60 (2), p.129-135

2007

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Orally Active Carbapenem Antibiotics I

Journal of antibiotics, 2005-12, Vol.58 (12), p.787-803

2005

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Combined effects of meropenem and aminoglycosides on Pseudomonas aeruginosa in vitro

Journal of antimicrobial chemotherapy, 2000-12, Vol.46 (6), p.901-904

2000

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β-lactamase非産生ampicillin耐性Haemophilus influenzaeおよびペニシリン耐性Streptococcus pneumoniaeに対するmempenemと各種抗菌薬のin vitro併用効果

The Japanese Journal of Antibiotics, 2005/04/25, Vol.58(2), pp.168-178

2005

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Structure-activity Relationships of Carbapenems to the Antagonism of the Antipseudomonal Activity of Other β-Lactam Agents and to the β-Lactamase Inducibility in Pseudomonas aeniginosa: Effects of 1β-Methyl Group and C-2 Side Chain

The Journal of Antibiotics, 1999/02/25, Vol.52(2), pp.142-149

1999

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AmBisome: relationship between the pharmacokinetic characteristics acquired by liposomal formulation and safety/efficacy

Novel Carbapenem Antibiotics for Parenteral and Oral Applications: In Vitro and In Vivo Activities of 2-Aryl Carbapenems and Their Pharmacokinetics in Laboratory Animals

Comparative study of the efficacy of liposomal amphotericin B and amphotericin B deoxycholate against six species of Zygomycetes in a murine lethal infection model

Pharmacodynamics of SMP-601 (PTZ601) against Vancomycin-Resistant Enterococcus faecium and Methicillin-Resistant Staphylococcus aureus in Neutropenic Murine Thigh Infection Models

Therapeutic effect of meropenem on an experimental guinea pig model of meningitis with type b β-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae

Experimental verification of the efficacy of optimized two-step infusion therapy with meropenem using an in vitro pharmacodynamic model and Monte Carlo simulation

In Vitro and In Vivo Antibacterial Activities of SM-216601, a New Broad-Spectrum Parenteral Carbapenem

The Mode of Action of 2-(Thiazol-2-ylthio)-1β-methylcarbapenems against Pseudomonas aeruginosa: The Impact of Outer Membrane Permeability and the Contribution of MexAB-OprM Efflux System

BACTERICIAL ACTIVITY OF CHLORHEXIDINE GLUCONATE AGAINST RECENT CLINICAL ISOLATES OF VARIOUS BACTERIAL SPECIES IN JAPAN

Orally active carbapenem antibiotics I. Antibacterial and pharmacokinetic potential of 2-phenyl and 2-thienylcarbapenems

Influence of Fungicidal Activity against Candida tropicalis on the Efficacy of Micafungin and Liposomal Amphotericin B in a Neutropenic Murine Lethal Infection Model

NDV-3ワクチンは，MRSA感染症の発症・重症化を克服し得るか

Therapeutic effect of meropenem on an experimental guinea pig model of meningitis with type b I2-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae

Structure-activity relationships of carbapenems to the antagonism of the antipseudomonal activity of other β-lactam agents and to the β-lactamase inducibility in Pseudomonas aeruginosa : Effects of 1β-methyl group and C-2 side chain

Structure-activity relationships of carbapenems to the antagonism of the antipseudomonal activity of other beta-lactam agents and to the beta-lactamase inducibility in Pseudomonas aeruginosa: effects of 1beta-methyl group and C-2 side chain

Comparative Study on the Efficacy of Liposomal Amphotericin B and Voriconazole in a Murine Pulmonary Aspergillosis Model

In vivo activity of liposomal amphotericin B against Exophiala dermatitidis in a murine lethal infection model

IN VITRO COMBINED EFFECT OF MEROPENEM AND VARIOUS ANTIMICROBIAL AGENTS AGAINST β-LACTAMASE-NONPRODUCING AMPICILLIN-RESISTANT Haemophilus influenzae AND PENICILLIN-RESISTANT Streptococcus pneumoniae

In vitro combined effect of meropenem and various antimicrobial agents against beta-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae and penicillin-resistant Streptococcus pneumoniae

The Mode of Action of 2-(Thiazol-2-ylthio)-1[beta]-methylcarbapenems against Pseudomonas aeruginosa: The Impact of Outer Membrane Permeability and the Contribution of MexAB-OprM Efflux System

The mode of action of 2-(thiazol-2-ylthio)-1beta-methylcarbapenems against Pseudomonas aeruginosa: the impact of outer membrane permeability and the contribution of MexAB-OprM efflux system

Orally Active Carbapenem Antibiotics I

Combined effects of meropenem and aminoglycosides on Pseudomonas aeruginosa in vitro

β-lactamase非産生ampicillin耐性Haemophilus influenzaeおよびペニシリン耐性Streptococcus pneumoniaeに対するmempenemと各種抗菌薬のin vitro併用効果

Structure-activity Relationships of Carbapenems to the Antagonism of the Antipseudomonal Activity of Other β-Lactam Agents and to the β-Lactamase Inducibility in Pseudomonas aeniginosa: Effects of 1β-Methyl Group and C-2 Side Chain

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