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Bioavailability of ACC‐9653 (Phenytoin Prodrug)

Epilepsia (Copenhagen), 1989-01, Vol.30 (s2), p.S27-S32

1989

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Performance of Human Mass Balance Studies with Stable Isotope-Labeled Drug and Continuous Flow-Isotope Ratio Mass Spectrometry: A Progress Report

Journal of clinical pharmacology, 1998-04, Vol.38 (4), p.309-314

1998

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Alternatives to Least Squares Linear Regression Analysis for Computation of Standard Curves for Quantitation by High Performance Liquid Chromatography: Applications to Clinical Pharmacology

Journal of clinical pharmacology, 1994-03, Vol.34 (3), p.242-249

1994

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Central levodopa metabolism in Parkinson's disease after administration of stable isotope-labeled levodopa

Annals of neurology, 1997-09, Vol.42 (3), p.300-304

1997

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Performance of Human Mass Balance/Metabolite Identification Studies Using Stable Isotope (13C, 15N) Labeling and Continuous-Flow Isotope-Ratio Mass Spectrometry as an Alternative to Radioactive Labeling Methods

Journal of clinical pharmacology, 1993-03, Vol.33 (3), p.246-252

1993

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Simultaneous separation and determination (in serum) of phenytoin and carbamazepine and their deuterated analogues by high-performance liquid chromatography—ultraviolet detection for tracer studies

Journal of Chromatography A, 1990-12, Vol.535 (1-2), p.271-277

1990

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Chronic benzodiazepine administration: IX. Attenuation of alprazolam discontinuation effects by carbamazepine

Biochemical pharmacology, 1991-12, Vol.42, p.S99-S104

1991

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Simultaneous determination of p-hydroxylated and dihydrodiol metabolites of phenytoin in urine by high-performance liquid chromatography

Journal of Chromatography A, 1990-12, Vol.535 (1-2), p.279-285

1990

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A Pharmacokinetic Rationale for Three Times Daily Administration of Ethotoin (Peganone®)

Journal of clinical pharmacology, 1989-03, Vol.29 (3), p.270-271

1989

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Chronic benzodiazepine administration

Biochemical pharmacology, 1991-12, Vol.42, p.S99-S104

1991

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Chapter 6 Mass spectrometry: Isotope ratio mass spectrometry

Pharmacochemistry Library, 1997, Vol.26, p.119-125

1997

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New Pharmacokinetic Methods: L Estimation of Mean Serum Concentration From Trough Serum Concentration

Journal of clinical pharmacology, 1990-06, Vol.30 (6), p.482-488

1990

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Chapter 22 Procurement of stable isotope-labeled pharmaceuticals

Pharmacochemistry Library, 1997, Vol.26, p.405-409

1997

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New Pharmacokinetic Methods III. Two Simple Tests for "Deep Pool Effect"

Journal of clinical pharmacology, 1990-08, Vol.30 (8), p.680-685

1990

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Mass Spectrometry: Preparation of Biologic Specimens

Journal of clinical pharmacology, 1986-07, Vol.26 (6), p.400-405

1986

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New Pharmacokinetic Methods II: Determination of the Presence or Absence of Product Inhibition in Drugs with Nonlinear Pharmacokinetics

Journal of clinical pharmacology, 1990-07, Vol.30 (7), p.578-584

1990

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Studies With Stable Isotopes II: Phenobarbital Pharmacokinetics During Monotherapy

Journal of clinical pharmacology, 1985-01, Vol.25 (1), p.51-58

1985

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Chapter 7 alternatives to mass spectrometry for quantitation of stable isotopes: High performance liquid chromatography with conventional ultraviolet detection

Pharmacochemistry Library, 1997, Vol.26, p.127-140

1997

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Studies With Stable Isotopes I: Changes in Phenytoin Pharmacokinetics and Biotransformation During Monotherapy

Journal of clinical pharmacology, 1985-01, Vol.25 (1), p.43-50

1985

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Estimation of the Elimination Half-Life of a Drug at Any Serum Concentration When the Km and Vmax of the Drug Are Known: Calculations and Validation With Phenytoin

Journal of clinical pharmacology, 1987-04, Vol.27 (4), p.318-320

1987

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Pharmacokinetics: Dose-Dependent Changes

Journal of clinical pharmacology, 1986-07, Vol.26 (6), p.463-468

1986

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Determination of the in Vivo Km and Vmax of a Drug With Tracer Studies

Journal of clinical pharmacology, 1987-04, Vol.27 (4), p.321-324

1987

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Estimation of the Elimination Half‐Life of a Drug at Any Serum Concentration When the K m and V max of the Drug Are Known: Calculations and Validation With Phenytoin

Journal of clinical pharmacology, 1987-04, Vol.27 (4), p.318-320

1987

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Determination of the in Vivo K m and V max of a Drug With Tracer Studies

Journal of clinical pharmacology, 1987-04, Vol.27 (4), p.321-324

1987

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Studies With Stable Isotopes III: Pharmacokinetics of Tracer Doses of Drug

Journal of clinical pharmacology, 1985-01, Vol.25 (1), p.59-63

1985

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Bioavailability of ACC‐9653 (Phenytoin Prodrug)

Performance of Human Mass Balance Studies with Stable Isotope-Labeled Drug and Continuous Flow-Isotope Ratio Mass Spectrometry: A Progress Report

Alternatives to Least Squares Linear Regression Analysis for Computation of Standard Curves for Quantitation by High Performance Liquid Chromatography: Applications to Clinical Pharmacology

Central levodopa metabolism in Parkinson's disease after administration of stable isotope-labeled levodopa

Performance of Human Mass Balance/Metabolite Identification Studies Using Stable Isotope (13C, 15N) Labeling and Continuous-Flow Isotope-Ratio Mass Spectrometry as an Alternative to Radioactive Labeling Methods

Simultaneous separation and determination (in serum) of phenytoin and carbamazepine and their deuterated analogues by high-performance liquid chromatography—ultraviolet detection for tracer studies

Chronic benzodiazepine administration: IX. Attenuation of alprazolam discontinuation effects by carbamazepine

Simultaneous determination of p-hydroxylated and dihydrodiol metabolites of phenytoin in urine by high-performance liquid chromatography

A Pharmacokinetic Rationale for Three Times Daily Administration of Ethotoin (Peganone®)

Chronic benzodiazepine administration

Chapter 6 Mass spectrometry: Isotope ratio mass spectrometry

New Pharmacokinetic Methods: L Estimation of Mean Serum Concentration From Trough Serum Concentration

Chapter 22 Procurement of stable isotope-labeled pharmaceuticals

New Pharmacokinetic Methods III. Two Simple Tests for "Deep Pool Effect"

Mass Spectrometry: Preparation of Biologic Specimens

New Pharmacokinetic Methods II: Determination of the Presence or Absence of Product Inhibition in Drugs with Nonlinear Pharmacokinetics

Studies With Stable Isotopes II: Phenobarbital Pharmacokinetics During Monotherapy

Chapter 7 alternatives to mass spectrometry for quantitation of stable isotopes: High performance liquid chromatography with conventional ultraviolet detection

Studies With Stable Isotopes I: Changes in Phenytoin Pharmacokinetics and Biotransformation During Monotherapy

Estimation of the Elimination Half-Life of a Drug at Any Serum Concentration When the Km and Vmax of the Drug Are Known: Calculations and Validation With Phenytoin

Pharmacokinetics: Dose-Dependent Changes

Determination of the in Vivo Km and Vmax of a Drug With Tracer Studies

Estimation of the Elimination Half‐Life of a Drug at Any Serum Concentration When the K m and V max of the Drug Are Known: Calculations and Validation With Phenytoin

Determination of the in Vivo K m and V max of a Drug With Tracer Studies

Studies With Stable Isotopes III: Pharmacokinetics of Tracer Doses of Drug

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