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Production of Site-Specific Antibody–Drug Conjugates Using Optimized Non-Natural Amino Acids in a Cell-Free Expression System

Bioconjugate chemistry, 2014-02, Vol.25 (2), p.351-361

2014

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Discovery of a potent, selective, and tumor-suppressing antibody antagonist of adenosine A2A receptor

PloS one, 2024, Vol.19 (6), p.e0301223

2024

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Discovery and design of G protein-coupled receptor targeting antibodies

Expert opinion on drug discovery, 2023-04, Vol.18 (4), p.417-428

2023

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Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage libraries

mAbs, 2022-01, Vol.14 (1), p.2002236-2002236

2022

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Functional GLP-1R antibodies identified from a synthetic GPCR-focused library demonstrate potent blood glucose control

mAbs, 2021-01, Vol.13 (1), p.1893425

2021

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RF1 attenuation enables efficient non-natural amino acid incorporation for production of homogeneous antibody drug conjugates

Scientific reports, 2017-06, Vol.7 (1), p.3026-13, Article 3026

2017

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Post-Exposure Protection in Mice against Sudan Virus by a Two Antibody Cocktail

Viruses, 2018-05, Vol.10 (6), p.286

2018

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Engineering toward a bacterial "endoplasmic reticulum" for the rapid expression of immunoglobulin proteins

mAbs, 2014-05, Vol.6 (3), p.671-678

2014

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Phage display technology and its impact in the discovery of novel protein-based drugs

Expert opinion on drug discovery, 2024-08, Vol.19 (8), p.887-915

2024

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Therapeutic peptides: technological advances driving peptides into development

Current opinion in biotechnology, 2006-12, Vol.17 (6), p.638-642

2006

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Methods to Make Homogenous Antibody Drug Conjugates

Pharmaceutical research, 2015-11, Vol.32 (11), p.3480-3493

2015

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Discovery of Fully Human Anti-MET Monoclonal Antibodies with Antitumor Activity against Colon Cancer Tumor Models In Vivo

Neoplasia (New York, N.Y.), 2009-04, Vol.11 (4), p.355,IN3-364,IN5

2009

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Discovery of STRO-002, a Novel Homogeneous ADC Targeting Folate Receptor Alpha, for the Treatment of Ovarian and Endometrial Cancers

Molecular cancer therapeutics, 2023-02, Vol.22 (2), p.155-167

2023

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Extracellular Antigen Processing and Presentation by Immature Dendritic Cells

Proceedings of the National Academy of Sciences - PNAS, 1999-12, Vol.96 (26), p.15056-15061

1999

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Malaria Derived Glycosylphosphatidylinositol Anchor Enhances Anti-Pfs25 Functional Antibodies That Block Malaria Transmission

Biochemistry (Easton), 2018-02, Vol.57 (5), p.516-519

2018

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Optimization of a glucagon-like peptide 1 receptor antagonist antibody for treatment of hyperinsulinism

Diabetes (New York, N.Y.), 2023-09, Vol.72 (9), p.1320-1329

2023

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A simplified and robust protocol for immunoglobulin expression in Escherichia coli cell-free protein synthesis systems

Biotechnology progress, 2015-05, Vol.31 (3), p.823-831

2015

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Toward a Ferrous Iron-Cleavable Linker for Antibody–Drug Conjugates

Molecular pharmaceutics, 2018-05, Vol.15 (5), p.2054-2059

2018

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Abundant Empty Class II MHC Molecules on the Surface of Immature Dendritic Cells

Proceedings of the National Academy of Sciences - PNAS, 1999-12, Vol.96 (26), p.15050-15055

1999

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Targeted Drug Delivery with an Integrin-Binding Knottin-Fc-MMAF Conjugate Produced by Cell-Free Protein Synthesis

Molecular cancer therapeutics, 2016-06, Vol.15 (6), p.1291-1300

2016

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Phage display-derived peptides as therapeutic alternatives to antibodies

Drug Discovery Today, 2004-06, Vol.9 (12), p.525-529

2004

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Identification of an ADAMTS-4 Cleavage Motif Using Phage Display Leads to the Development of Fluorogenic Peptide Substrates and Reveals Matrilin-3 as a Novel Substrate

The Journal of biological chemistry, 2007-04, Vol.282 (15), p.11101-11109

2007

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Production of bispecific antibodies in "knobs-into-holes" using a cell-free expression system

mAbs, 2015-01, Vol.7 (1), p.231-242

2015

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Development of Mammalian Serum Albumin Affinity Purification Media by Peptide Phage Display

Biotechnology progress, 2002, Vol.18 (2), p.182-192

2002

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RP-HPLC DAR Characterization of Site-Specific Antibody Drug Conjugates Produced in a Cell-Free Expression System

Organic process research & development, 2016-06, Vol.20 (6), p.1034-1043

2016

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Production of Site-Specific Antibody–Drug Conjugates Using Optimized Non-Natural Amino Acids in a Cell-Free Expression System

Discovery of a potent, selective, and tumor-suppressing antibody antagonist of adenosine A2A receptor

Discovery and design of G protein-coupled receptor targeting antibodies

Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage libraries

Functional GLP-1R antibodies identified from a synthetic GPCR-focused library demonstrate potent blood glucose control

RF1 attenuation enables efficient non-natural amino acid incorporation for production of homogeneous antibody drug conjugates

Post-Exposure Protection in Mice against Sudan Virus by a Two Antibody Cocktail

Engineering toward a bacterial "endoplasmic reticulum" for the rapid expression of immunoglobulin proteins

Phage display technology and its impact in the discovery of novel protein-based drugs

Therapeutic peptides: technological advances driving peptides into development

Methods to Make Homogenous Antibody Drug Conjugates

Discovery of Fully Human Anti-MET Monoclonal Antibodies with Antitumor Activity against Colon Cancer Tumor Models In Vivo

Discovery of STRO-002, a Novel Homogeneous ADC Targeting Folate Receptor Alpha, for the Treatment of Ovarian and Endometrial Cancers

Extracellular Antigen Processing and Presentation by Immature Dendritic Cells

Malaria Derived Glycosylphosphatidylinositol Anchor Enhances Anti-Pfs25 Functional Antibodies That Block Malaria Transmission

Optimization of a glucagon-like peptide 1 receptor antagonist antibody for treatment of hyperinsulinism

A simplified and robust protocol for immunoglobulin expression in Escherichia coli cell-free protein synthesis systems

Toward a Ferrous Iron-Cleavable Linker for Antibody–Drug Conjugates

Abundant Empty Class II MHC Molecules on the Surface of Immature Dendritic Cells

Targeted Drug Delivery with an Integrin-Binding Knottin-Fc-MMAF Conjugate Produced by Cell-Free Protein Synthesis

Phage display-derived peptides as therapeutic alternatives to antibodies

Identification of an ADAMTS-4 Cleavage Motif Using Phage Display Leads to the Development of Fluorogenic Peptide Substrates and Reveals Matrilin-3 as a Novel Substrate

Production of bispecific antibodies in "knobs-into-holes" using a cell-free expression system

Development of Mammalian Serum Albumin Affinity Purification Media by Peptide Phage Display

RP-HPLC DAR Characterization of Site-Specific Antibody Drug Conjugates Produced in a Cell-Free Expression System

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