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Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomes

Xenobiotica, 2009-01, Vol.39 (1), p.11-21

2009

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Lactobacillus rhamnosus Strain GG Reduces Aflatoxin B₁ Transport, Metabolism, and Toxicity in Caco-2 Cells

Applied and Environmental Microbiology, 2007-06, Vol.73 (12), p.3958-3964

2007

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New potent and selective cytochrome P450 2B6 (CYP2B6) inhibitors based on three‐dimensional quantitative structure‐activity relationship (3D‐QSAR) analysis

British journal of pharmacology, 2007-04, Vol.150 (7), p.932-942

2007

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Identification of inhibitors of the nicotine metabolising CYP2A6 enzyme--an in silico approach

The pharmacogenomics journal, 2008-10, Vol.8 (5), p.328-338

2008

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Nicotine metabolism and urinary elimination in mouse: in vitro and in vivo

Xenobiotica, 2008-01, Vol.38 (1), p.34-47

2008

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More potent inhibition of human CYP2A6 than mouse CYP2A5 enzyme activities by derivatives of phenylethylamine and benzaldehyde

Xenobiotica, 2003-05, Vol.33 (5), p.529-539

2003

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Lactobacillus rhamnosus Strain GG Modulates Intestinal Absorption, Fecal Excretion, and Toxicity of Aflatoxin B₁ in Rats

Applied and Environmental Microbiology, 2006-11, Vol.72 (11), p.7398-7400

2006

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Pronounced differences in inhibition potency of lactone and non-lactone compounds for mouse and human coumarin 7-hydroxylases (CYP2A5 and CYP2A6)

Xenobiotica, 2000, Vol.30 (1), p.81-92

2000

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Cytochromes P450 2A6, 2E1, and 3A and production of protein-aldehyde adducts in the liver of patients with alcoholic and non-alcoholic liver diseases

Journal of hepatology, 2000-12, Vol.33 (6), p.893-901

2000

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Structural function of residue-209 in coumarin 7-hydroxylase (P450coh). Enzyme-kinetic studies and site-directed mutagenesis

The Journal of biological chemistry, 1991-09, Vol.266 (25), p.16431-16435

1991

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Site-directed mutagenesis of mouse steroid 7α-hydroxylase (cytochrome P-4507α) : role of residue-209 in determining steroid-cytochrome P-450 interaction

Biochemical journal, 1993-04, Vol.291 (2), p.569-573

1993

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The inhibition of CYP enzymes in mouse and human liver by pilocarpine

British journal of pharmacology, 1995-02, Vol.114 (4), p.832-836

1995

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Competitive inhibition of coumarin 7-hydroxylation by pilocarpine and its interaction with mouse CYP 2A5 and human CYP 2A6

British journal of pharmacology, 1995-11, Vol.116 (6), p.2625-2630

1995

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A sensitive microassay reveals marked regional differences in the capacity of rat brain to generate carbon monoxide

Brain research, 1995-10, Vol.694 (1), p.246-252

1995

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Roles of residues 129 and 209 in the alteration by cytochrome b5 of hydroxylase activities in mouse 2A P450S

Biochemistry (Easton), 1992-11, Vol.31 (46), p.11519-11523

1992

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Lactobacillus rhamnosus Strain GG Reduces Aflatoxin B 1 Transport, Metabolism, and Toxicity in Caco-2 Cells

Applied and environmental microbiology, 2007-06, Vol.73 (12), p.3958-3964

2007

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Structural alteration of mouse P450coh by mutation of glycine-207 to proline : spin equilibrium, enzyme kinetics, and heat sensitivity

Biochemical journal, 1993-08, Vol.294 (1), p.31-34

1993

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The role of CYP enzymes in cocaine-induced liver damage

Archives of toxicology, 1995-03, Vol.69 (5), p.287-290

1995

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Lactobacillus rhamnosus Strain GG Modulates Intestinal Absorption, Fecal Excretion, and Toxicity of Aflatoxin B 1 in Rats

Applied and environmental microbiology, 2006-11, Vol.72 (11), p.7398-7400

2006

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Alteration of the substrate specificity of mouse 2A P450s by the identity of residue-209: Steroid-binding site and orientation

Journal of steroid biochemistry and molecular biology, 1992-12, Vol.43 (8), p.1031-1036

1992

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Pyrazole as a modifier of liver microsomal monooxygenase in DBA/2N and AKR/J mice

Biochemical pharmacology, 1987-11, Vol.36 (22), p.3993-3997

1987

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CYP enzymes catalyze the formation of a terminal olefin from 2-ethylhexanoic acid in rat and human liver

Human & experimental toxicology, 1996-05, Vol.15 (5), p.435-442

1996

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Probiotic supplementation reduces a biomarker for increased risk of liver cancer in young men from Southern China

The American journal of clinical nutrition, 2006-05, Vol.83 (5), p.1199-1203

2006

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Design, Synthesis, and In Vitro Evaluation of Carbamate Derivatives of 2-Benzoxazolyl- and 2-Benzothiazolyl-(3-hydroxyphenyl)-methanones as Novel Fatty Acid Amide Hydrolase Inhibitors

Journal of medicinal chemistry, 2007-08, Vol.50 (17), p.4236-4242

2007

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Predictive Three-Dimensional Quantitative Structure−Activity Relationship of Cytochrome P450 1A2 Inhibitors

Journal of medicinal chemistry, 2005-06, Vol.48 (11), p.3808-3815

2005

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Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomes

Lactobacillus rhamnosus Strain GG Reduces Aflatoxin B₁ Transport, Metabolism, and Toxicity in Caco-2 Cells

New potent and selective cytochrome P450 2B6 (CYP2B6) inhibitors based on three‐dimensional quantitative structure‐activity relationship (3D‐QSAR) analysis

Identification of inhibitors of the nicotine metabolising CYP2A6 enzyme--an in silico approach

Nicotine metabolism and urinary elimination in mouse: in vitro and in vivo

More potent inhibition of human CYP2A6 than mouse CYP2A5 enzyme activities by derivatives of phenylethylamine and benzaldehyde

Lactobacillus rhamnosus Strain GG Modulates Intestinal Absorption, Fecal Excretion, and Toxicity of Aflatoxin B₁ in Rats

Pronounced differences in inhibition potency of lactone and non-lactone compounds for mouse and human coumarin 7-hydroxylases (CYP2A5 and CYP2A6)

Cytochromes P450 2A6, 2E1, and 3A and production of protein-aldehyde adducts in the liver of patients with alcoholic and non-alcoholic liver diseases

Structural function of residue-209 in coumarin 7-hydroxylase (P450coh). Enzyme-kinetic studies and site-directed mutagenesis

Site-directed mutagenesis of mouse steroid 7α-hydroxylase (cytochrome P-4507α) : role of residue-209 in determining steroid-cytochrome P-450 interaction

The inhibition of CYP enzymes in mouse and human liver by pilocarpine

Competitive inhibition of coumarin 7-hydroxylation by pilocarpine and its interaction with mouse CYP 2A5 and human CYP 2A6

A sensitive microassay reveals marked regional differences in the capacity of rat brain to generate carbon monoxide

Roles of residues 129 and 209 in the alteration by cytochrome b5 of hydroxylase activities in mouse 2A P450S

Lactobacillus rhamnosus Strain GG Reduces Aflatoxin B 1 Transport, Metabolism, and Toxicity in Caco-2 Cells

Structural alteration of mouse P450coh by mutation of glycine-207 to proline : spin equilibrium, enzyme kinetics, and heat sensitivity

The role of CYP enzymes in cocaine-induced liver damage

Lactobacillus rhamnosus Strain GG Modulates Intestinal Absorption, Fecal Excretion, and Toxicity of Aflatoxin B 1 in Rats

Alteration of the substrate specificity of mouse 2A P450s by the identity of residue-209: Steroid-binding site and orientation

Pyrazole as a modifier of liver microsomal monooxygenase in DBA/2N and AKR/J mice

CYP enzymes catalyze the formation of a terminal olefin from 2-ethylhexanoic acid in rat and human liver

Probiotic supplementation reduces a biomarker for increased risk of liver cancer in young men from Southern China

Design, Synthesis, and In Vitro Evaluation of Carbamate Derivatives of 2-Benzoxazolyl- and 2-Benzothiazolyl-(3-hydroxyphenyl)-methanones as Novel Fatty Acid Amide Hydrolase Inhibitors

Predictive Three-Dimensional Quantitative Structure−Activity Relationship of Cytochrome P450 1A2 Inhibitors

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