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Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity

The Journal of physiology, 2016-04, Vol.594 (8), p.2001-2024

2016

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Physiological Aging: Links Among Adipose Tissue Dysfunction, Diabetes, and Frailty

Physiology (Bethesda, Md.), 2017-01, Vol.32 (1), p.9-19

2017

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Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study

EBioMedicine, 2019-02, Vol.40, p.554-563

2019

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Testing the Geroscience Hypothesis: Early Days

The journals of gerontology. Series A, Biological sciences and medical sciences, 2020-01, Vol.75 (1), p.99-101

2020

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Putting epigenetic biomarkers to the test for clinical trials

eLife, 2020-06, Vol.9

2020

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A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup

GeroScience, 2018-12, Vol.40 (5-6), p.419-436

2018

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Comparative Approaches to Understanding the Relation Between Aging and Physical Function

The journals of gerontology. Series A, Biological sciences and medical sciences, 2016-10, Vol.71 (10), p.1243-1253

2016

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Adipose Tissue Quality in Aging: How Structural and Functional Aspects of Adipose Tissue Impact Skeletal Muscle Quality

Nutrients, 2019-10, Vol.11 (11), p.2553

2019

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Lipotoxicity, aging, and muscle contractility: does fiber type matter?

GeroScience, 2019-06, Vol.41 (3), p.297-308

2019

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Fatigability of the dorsiflexors and associations among multiple domains of motor function in young and old adults

Experimental gerontology, 2014-07, Vol.55, p.92-101

2014

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Development of Clinical Trials to Extend Healthy Lifespan

Cardiovascular endocrinology & metabolism, 2018-12, Vol.7 (4), p.80-83

2018

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Long-term dasatinib plus quercetin effects on aging outcomes and inflammation in nonhuman primates: implications for senolytic clinical trial design

GeroScience, 2023-10, Vol.45 (5), p.2785-2803

2023

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Sodium nitrite supplementation improves motor function and skeletal muscle inflammatory profile in old male mice

Journal of applied physiology (1985), 2015-01, Vol.118 (2), p.163-169

2015

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Strategies to reduce the onset of sleeve gastrectomy associated bone loss (STRONG BONES): Trial design and methods

Contemporary clinical trials communications, 2023-08, Vol.34, p.101181-101181, Article 101181

2023

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Translational research on aging and adaptations to exercise

Experimental gerontology, 2022-09, Vol.166, p.111872-111872, Article 111872

2022

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Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review

Journal of the American College of Cardiology, 2021-09, Vol.78 (11), p.1166-1187

2021

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Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance

Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (9), p.2313-2318

2017

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An Examination of Whether Diabetes Control and Treatments Are Associated With Change in Frailty Index Across 8 Years: An Ancillary Exploratory Study From the Action for Health in Diabetes (Look AHEAD) Trial

Diabetes care, 2023-03, Vol.46 (3), p.519-525

2023

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Validation of biomarkers of aging

Nature medicine, 2024-02, Vol.30 (2), p.360-372

2024

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Evaluating Health Span in Preclinical Models of Aging and Disease: Guidelines, Challenges, and Opportunities for Geroscience

The journals of gerontology. Series A, Biological sciences and medical sciences, 2016-11, Vol.71 (11), p.1395-1406

2016

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Association of a Blood-Based Aging Biomarker Index With Death and Chronic Disease: Cardiovascular Health Study

The journals of gerontology. Series A, Biological sciences and medical sciences, 2024-02, Vol.79 (2)

2024

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Caloric Restriction Intervention Alters Specific Circulating Biomarkers of the Senescence-Associated Secretome in Middle-Aged and Older Adults With Obesity and Prediabetes in an 18-Week Randomized Controlled Trial

The journals of gerontology. Series A, Biological sciences and medical sciences, 2024-01, Vol.79 (1)

2024

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Associations between regional adipose tissue distribution and skeletal muscle bioenergetics in older men and women

Obesity (Silver Spring, Md.), 2024-06, Vol.32 (6), p.1125-1135

2024

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Psychosocial stress increases risk for type 2 diabetes in female cynomolgus macaques consuming a western diet

Psychoneuroendocrinology, 2022-05, Vol.139, p.105706-105706, Article 105706

2022

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Lifelong physical activity attenuates age- and Western-style diet-related declines in physical function and adverse changes in skeletal muscle mass and inflammation

Experimental gerontology, 2022-01, Vol.157, p.111632-111632, Article 111632

2022

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Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity

Physiological Aging: Links Among Adipose Tissue Dysfunction, Diabetes, and Frailty

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study

Testing the Geroscience Hypothesis: Early Days

Putting epigenetic biomarkers to the test for clinical trials

A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup

Comparative Approaches to Understanding the Relation Between Aging and Physical Function

Adipose Tissue Quality in Aging: How Structural and Functional Aspects of Adipose Tissue Impact Skeletal Muscle Quality

Lipotoxicity, aging, and muscle contractility: does fiber type matter?

Fatigability of the dorsiflexors and associations among multiple domains of motor function in young and old adults

Development of Clinical Trials to Extend Healthy Lifespan

Long-term dasatinib plus quercetin effects on aging outcomes and inflammation in nonhuman primates: implications for senolytic clinical trial design

Sodium nitrite supplementation improves motor function and skeletal muscle inflammatory profile in old male mice

Strategies to reduce the onset of sleeve gastrectomy associated bone loss (STRONG BONES): Trial design and methods

Translational research on aging and adaptations to exercise

Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review

Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance

An Examination of Whether Diabetes Control and Treatments Are Associated With Change in Frailty Index Across 8 Years: An Ancillary Exploratory Study From the Action for Health in Diabetes (Look AHEAD) Trial

Validation of biomarkers of aging

Evaluating Health Span in Preclinical Models of Aging and Disease: Guidelines, Challenges, and Opportunities for Geroscience

Association of a Blood-Based Aging Biomarker Index With Death and Chronic Disease: Cardiovascular Health Study

Caloric Restriction Intervention Alters Specific Circulating Biomarkers of the Senescence-Associated Secretome in Middle-Aged and Older Adults With Obesity and Prediabetes in an 18-Week Randomized Controlled Trial

Associations between regional adipose tissue distribution and skeletal muscle bioenergetics in older men and women

Psychosocial stress increases risk for type 2 diabetes in female cynomolgus macaques consuming a western diet

Lifelong physical activity attenuates age- and Western-style diet-related declines in physical function and adverse changes in skeletal muscle mass and inflammation

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