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Glycosylation-Dependent Lectin-Receptor Interactions Preserve Angiogenesis in Anti-VEGF Refractory Tumors

Cell, 2014-02, Vol.156 (4), p.744-758

2014

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Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

The FASEB journal, 2008-04, Vol.22 (4), p.954-965

2008

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A Stromal Niche Defined by Expression of the Transcription Factor WT1 Mediates Programming and Homeostasis of Cavity-Resident Macrophages

Immunity (Cambridge, Mass.), 2019-07, Vol.51 (1), p.119-130.e5

2019

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Transcription factor Etv5 is essential for the maintenance of alveolar type II cells

Proceedings of the National Academy of Sciences - PNAS, 2017-04, Vol.114 (15), p.3903-3908

2017

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Distinct Thresholds Govern Myc's Biological Output In Vivo

Cancer cell, 2008-12, Vol.14 (6), p.447-457

2008

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Mechanisms of MYC stabilization in human malignancies

Cell cycle (Georgetown, Tex.), 2008-03, Vol.7 (5), p.592-596

2008

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Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors

PloS one, 2017-10, Vol.12 (10), p.e0185862

2017

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Influence of tumour micro-environment heterogeneity on therapeutic response

Nature (London), 2013-09, Vol.501 (7467), p.346-354

2013

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Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF–induced neutrophil recruitment

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (15), p.6079-6084

2013

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BIM Is the Primary Mediator of MYC-Induced Apoptosis in Multiple Solid Tissues

Cell reports (Cambridge), 2014-09, Vol.8 (5), p.1347-1353

2014

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CRAF dimerization with ARAF regulates KRAS-driven tumor growth

Cell reports (Cambridge), 2022-02, Vol.38 (6), p.110351-110351, Article 110351

2022

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Manic Fringe deficiency imposes Jagged1 addiction to intestinal tumor cells

Nature communications, 2018-07, Vol.9 (1), p.2992-13, Article 2992

2018

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Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1

Cancer discovery, 2013-02, Vol.3 (2), p.182-197

2013

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Translational value of mouse models in oncology drug development

Nature medicine, 2015-05, Vol.21 (5), p.431-439

2015

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Harnessing the predictive power of preclinical models for oncology drug development

Nature reviews. Drug discovery, 2022-02, Vol.21 (2), p.99-114

2022

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EHMT2 methyltransferase governs cell identity in the lung and is required for KRAS G12D tumor development and propagation

eLife, 2022-08, Vol.11

2022

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Modeling targeted inhibition of MEK and PI3 kinase in human pancreatic cancer

Molecular cancer therapeutics, 2015-01, Vol.14 (1), p.40-47

2015

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A novel small molecule inhibitor of CD73 triggers immune-mediated multiple myeloma cell death

Blood cancer journal (New York), 2024-04, Vol.14 (1), p.58-58, Article 58

2024

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Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15 + Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy

Cancer discovery, 2020-02, Vol.10 (2), p.232-253

2020

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Castration-Resistant Lgr5+ Cells Are Long-Lived Stem Cells Required for Prostatic Regeneration

Stem cell reports, 2015-05, Vol.4 (5), p.768-779

2015

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CD3 bispecific antibody–induced cytokine release is dispensable for cytotoxic T cell activity

Science translational medicine, 2019-09, Vol.11 (508)

2019

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p53 - a Jack of all trades but master of none

Nature reviews. Cancer, 2009-11, Vol.9 (11), p.821-829

2009

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PME-1 Protects Extracellular Signal-Regulated Kinase Pathway Activity from Protein Phosphatase 2A―Mediated Inactivation in Human Malignant Glioma

Cancer research (Chicago, Ill.), 2009-04, Vol.69 (7), p.2870-2877

2009

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Automated segmentation of lungs and lung tumors in mouse micro-CT scans

iScience, 2022-12, Vol.25 (12), p.105712-105712, Article 105712

2022

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Acute Overexpression of Myc in Intestinal Epithelium Recapitulates Some but Not All the Changes Elicited by Wnt/β-Catenin Pathway Activation

Molecular and Cellular Biology, 2009-10, Vol.29 (19), p.5306-5315

2009

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Glycosylation-Dependent Lectin-Receptor Interactions Preserve Angiogenesis in Anti-VEGF Refractory Tumors

Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

A Stromal Niche Defined by Expression of the Transcription Factor WT1 Mediates Programming and Homeostasis of Cavity-Resident Macrophages

Transcription factor Etv5 is essential for the maintenance of alveolar type II cells

Distinct Thresholds Govern Myc's Biological Output In Vivo

Mechanisms of MYC stabilization in human malignancies

Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors

Influence of tumour micro-environment heterogeneity on therapeutic response

Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF–induced neutrophil recruitment

BIM Is the Primary Mediator of MYC-Induced Apoptosis in Multiple Solid Tissues

CRAF dimerization with ARAF regulates KRAS-driven tumor growth

Manic Fringe deficiency imposes Jagged1 addiction to intestinal tumor cells

Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1

Translational value of mouse models in oncology drug development

Harnessing the predictive power of preclinical models for oncology drug development

EHMT2 methyltransferase governs cell identity in the lung and is required for KRAS G12D tumor development and propagation

Modeling targeted inhibition of MEK and PI3 kinase in human pancreatic cancer

A novel small molecule inhibitor of CD73 triggers immune-mediated multiple myeloma cell death

Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15 + Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy

Castration-Resistant Lgr5+ Cells Are Long-Lived Stem Cells Required for Prostatic Regeneration

CD3 bispecific antibody–induced cytokine release is dispensable for cytotoxic T cell activity

p53 - a Jack of all trades but master of none

PME-1 Protects Extracellular Signal-Regulated Kinase Pathway Activity from Protein Phosphatase 2A―Mediated Inactivation in Human Malignant Glioma

Automated segmentation of lungs and lung tumors in mouse micro-CT scans

Acute Overexpression of Myc in Intestinal Epithelium Recapitulates Some but Not All the Changes Elicited by Wnt/β-Catenin Pathway Activation

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