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Ectopic overexpression of LAPTM5 results in lysosomal targeting and induces Mcl-1 down-regulation, Bak activation, and mitochondria-dependent apoptosis in human HeLa cells

PloS one, 2017-05, Vol.12 (5), p.e0176544-e0176544

2017

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Cytoprotective effect of 2-carbomethoxy-2,3-epoxy-3-prenyl-1,4-naphthoquinone (CMEP-NQ) is mediated by the inhibition of BAK-dependent mitochondrial apoptosis pathway

PloS one, 2018-10, Vol.13 (10), p.e0204585-e0204585

2018

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Tumor suppressor protein p53-mediated repression of human mitotic centromere-associated kinesin gene expression is exerted via down-regulation of Sp1 level

PloS one, 2017-12, Vol.12 (12), p.e0189698

2017

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Anti-inflammatory action of 2-carbomethoxy-2,3-epoxy-3-prenyl-1,4-naphthoquinone (CMEP-NQ) suppresses both the MyD88-dependent and TRIF-dependent pathways of TLR4 signaling in LPS-stimulated RAW264.7 cells

Journal of ethnopharmacology, 2017-06, Vol.205, p.103-115

2017

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Enhancement of Quercetin-Induced Apoptosis by Cotreatment with Autophagy Inhibitor Is Associated with Augmentation of BAK-Dependent Mitochondrial Pathway in Jurkat T Cells

Oxidative medicine and cellular longevity, 2019, Vol.2019 (2019), p.1-16

2019

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Activation of Nrf2 by dimethyl fumarate improves vascular calcification

Vascular pharmacology, 2014-10, Vol.63 (1), p.29-36

2014

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Clinical Implication of Serine Metabolism-Associated Enzymes in Colon Cancer

Oncology, 2015-01, Vol.89 (6), p.351-359

2015

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Pro-Apoptotic Role of the Human YPEL5 Gene Identified by Functional Complementation of a Yeast moh1Δ Mutation

Journal of microbiology and biotechnology, 2017-03, Vol.27 (3), p.633-643

2017

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Pharmacologic Inhibition of Autophagy Sensitizes Human Acute Leukemia Jurkat T Cells to Acacetin-Induced Apoptosis

Journal of microbiology and biotechnology, 2017-01, Vol.27 (1), p.197-205

2017

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Diverse CD8+ T-cell responses to renal cell carcinoma antigens in patients treated with an autologous granulocyte-macrophage colony-stimulating factor gene-transduced renal tumor cell vaccine

Cancer research (Chicago, Ill.), 2005-02, Vol.65 (3), p.1079-1088

2005

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Tumor Suppressor Protein p53 Promotes 2-Methoxyestradiol-Induced Activation of Bak and Bax, Leading to Mitochondria-Dependent Apoptosis in Human Colon Cancer HCT116 Cells

Journal of microbiology and biotechnology, 2014-12, Vol.24 (12), p.1654-1663

2014

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Pro-Apoptotic Role of the Human YPEL5 Gene Identified by Functional Complementation of a Yeast moh1 Δ Mutation

Journal of Microbiology and Biotechnology, 2017, 27(3), , pp.633-643

2017

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Positive regulation of promoter activity of human 3-phosphoglycerate dehydrogenase (PHGDH) gene is mediated by transcription factors Sp1 and NF-Y

Gene, 2008-05, Vol.414 (1), p.106-114

2008

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Apoptogenic activity of 2α,3α-dihydroxyurs-12-ene-28-oic acid from Prunella vulgaris var. lilacina is mediated via mitochondria-dependent activation of caspase cascade regulated by Bcl-2 in human acute leukemia Jurkat T cells

Journal of ethnopharmacology, 2011-06, Vol.135 (3), p.626-635

2011

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Mollugin induces apoptosis in human Jurkat T cells through endoplasmic reticulum stress-mediated activation of JNK and caspase-12 and subsequent activation of mitochondria-dependent caspase cascade regulated by Bcl-xL

Toxicology and applied pharmacology, 2009-12, Vol.241 (2), p.210-220

2009

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Monoterpenoids from the aerial parts of Aruncus dioicus var. kamtschaticus and their antioxidant and cytotoxic activities

Bioorganic & medicinal chemistry letters, 2011-06, Vol.21 (11), p.3252-3256

2011

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Cytotoxic Constituents from the Leaves of Zanthoxylum schinifolium

Bulletin of the Korean Chemical Society, 2010, 31(4), , pp.1081-1084

2010

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Antisense targeting of TGF-β1 augments BMP-induced upregulation of osteopontin, type I collagen and Cbfa1 in human Saos-2 cells

Experimental cell research, 2007-04, Vol.313 (7), p.1415-1425

2007

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Kaempferol Activates G 2 -Checkpoint of the Cell Cycle Resulting in G 2 -Arrest and Mitochondria-Dependent Apoptosis in Human Acute Leukemia Jurkat T Cells

Journal of microbiology and biotechnology, 2016, Vol.26 (2), p.287-294

2016

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L-Cysteine mitigates ROS-induced apoptosis and neurocognitive deficits by protecting against endoplasmic reticulum stress and mitochondrial dysfunction in mouse neuronal cells

Biomedicine & pharmacotherapy, 2024-11, Vol.180, p.117538, Article 117538

2024

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Effect of mollugin on apoptosis and adipogenesis of 3T3-L1 preadipocytes

Phytotherapy research, 2011-05, Vol.25 (5), p.724-731

2011

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Induction of microtubule-damage, mitotic arrest, Bcl-2 phosphorylation, Bak activation, and mitochondria-dependent caspase cascade is involved in human Jurkat T-cell apoptosis by aruncin B from Aruncus dioicus var. kamtschaticus

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (2), p.945-953

2012

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l-Serine protects mouse hippocampal neuronal HT22 cells against oxidative stress-mediated mitochondrial damage and apoptotic cell death

Free radical biology & medicine, 2019-09, Vol.141, p.447-460

2019

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17α-Estradiol arrests cell cycle progression at G2/M and induces apoptotic cell death in human acute leukemia Jurkat T cells

Toxicology and applied pharmacology, 2008-09, Vol.231 (3), p.401-412

2008

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Proteasome inhibitor MG132-induced apoptosis via ER stress-mediated apoptotic pathway and its potentiation by protein tyrosine kinase p56lck in human Jurkat T cells

Biochemical pharmacology, 2011-11, Vol.82 (9), p.1110-1125

2011

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Ectopic overexpression of LAPTM5 results in lysosomal targeting and induces Mcl-1 down-regulation, Bak activation, and mitochondria-dependent apoptosis in human HeLa cells

Cytoprotective effect of 2-carbomethoxy-2,3-epoxy-3-prenyl-1,4-naphthoquinone (CMEP-NQ) is mediated by the inhibition of BAK-dependent mitochondrial apoptosis pathway

Tumor suppressor protein p53-mediated repression of human mitotic centromere-associated kinesin gene expression is exerted via down-regulation of Sp1 level

Anti-inflammatory action of 2-carbomethoxy-2,3-epoxy-3-prenyl-1,4-naphthoquinone (CMEP-NQ) suppresses both the MyD88-dependent and TRIF-dependent pathways of TLR4 signaling in LPS-stimulated RAW264.7 cells

Enhancement of Quercetin-Induced Apoptosis by Cotreatment with Autophagy Inhibitor Is Associated with Augmentation of BAK-Dependent Mitochondrial Pathway in Jurkat T Cells

Activation of Nrf2 by dimethyl fumarate improves vascular calcification

Clinical Implication of Serine Metabolism-Associated Enzymes in Colon Cancer

Pro-Apoptotic Role of the Human YPEL5 Gene Identified by Functional Complementation of a Yeast moh1Δ Mutation

Pharmacologic Inhibition of Autophagy Sensitizes Human Acute Leukemia Jurkat T Cells to Acacetin-Induced Apoptosis

Diverse CD8+ T-cell responses to renal cell carcinoma antigens in patients treated with an autologous granulocyte-macrophage colony-stimulating factor gene-transduced renal tumor cell vaccine

Tumor Suppressor Protein p53 Promotes 2-Methoxyestradiol-Induced Activation of Bak and Bax, Leading to Mitochondria-Dependent Apoptosis in Human Colon Cancer HCT116 Cells

Pro-Apoptotic Role of the Human YPEL5 Gene Identified by Functional Complementation of a Yeast moh1 Δ Mutation

Positive regulation of promoter activity of human 3-phosphoglycerate dehydrogenase (PHGDH) gene is mediated by transcription factors Sp1 and NF-Y

Apoptogenic activity of 2α,3α-dihydroxyurs-12-ene-28-oic acid from Prunella vulgaris var. lilacina is mediated via mitochondria-dependent activation of caspase cascade regulated by Bcl-2 in human acute leukemia Jurkat T cells

Mollugin induces apoptosis in human Jurkat T cells through endoplasmic reticulum stress-mediated activation of JNK and caspase-12 and subsequent activation of mitochondria-dependent caspase cascade regulated by Bcl-xL

Monoterpenoids from the aerial parts of Aruncus dioicus var. kamtschaticus and their antioxidant and cytotoxic activities

Cytotoxic Constituents from the Leaves of Zanthoxylum schinifolium

Antisense targeting of TGF-β1 augments BMP-induced upregulation of osteopontin, type I collagen and Cbfa1 in human Saos-2 cells

Kaempferol Activates G 2 -Checkpoint of the Cell Cycle Resulting in G 2 -Arrest and Mitochondria-Dependent Apoptosis in Human Acute Leukemia Jurkat T Cells

L-Cysteine mitigates ROS-induced apoptosis and neurocognitive deficits by protecting against endoplasmic reticulum stress and mitochondrial dysfunction in mouse neuronal cells

Effect of mollugin on apoptosis and adipogenesis of 3T3-L1 preadipocytes

Induction of microtubule-damage, mitotic arrest, Bcl-2 phosphorylation, Bak activation, and mitochondria-dependent caspase cascade is involved in human Jurkat T-cell apoptosis by aruncin B from Aruncus dioicus var. kamtschaticus

l-Serine protects mouse hippocampal neuronal HT22 cells against oxidative stress-mediated mitochondrial damage and apoptotic cell death

17α-Estradiol arrests cell cycle progression at G2/M and induces apoptotic cell death in human acute leukemia Jurkat T cells

Proteasome inhibitor MG132-induced apoptosis via ER stress-mediated apoptotic pathway and its potentiation by protein tyrosine kinase p56lck in human Jurkat T cells

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