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The delivery of therapeutic oligonucleotides

Nucleic acids research, 2016-08, Vol.44 (14), p.6518-6548

Juliano, Rudolph L

2016

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Cellular Uptake and Intracellular Trafficking of Antisense and siRNA Oligonucleotides

Bioconjugate chemistry, 2012-02, Vol.23 (2), p.147-157

2012

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Chemical Manipulation of the Endosome Trafficking Machinery: Implications for Oligonucleotide Delivery

Biomedicines, 2021-05, Vol.9 (5), p.512

Juliano, Rudolph L.

2021

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Addressing cancer signal transduction pathways with antisense and siRNA oligonucleotides

NAR cancer, 2020-09, Vol.2 (3)

Juliano, Rudolph L

2020

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Enhanced delivery of peptide-morpholino oligonucleotides with a small molecule to correct splicing defects in the lung

Nucleic acids research, 2021-06, Vol.49 (11), p.6100-6113

2021

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Conditional Control of Alternative Splicing through Light-Triggered Splice-Switching Oligonucleotides

Journal of the American Chemical Society, 2015-03, Vol.137 (10), p.3656-3662

2015

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Cytosolic Delivery of Macromolecules in Live Human Cells Using the Combined Endosomal Escape Activities of a Small Molecule and Cell Penetrating Peptides

ACS chemical biology, 2019-12, Vol.14 (12), p.2641-2651

2019

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Multicellular Tumor Spheroids as a Model for Assessing Delivery of Oligonucleotides in Three Dimensions

Molecular therapy. Nucleic acids, 2014-03, Vol.3 (3), p.e153-e153, Article e153

2014

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Unconventional internalization mechanisms underlying functional delivery of antisense oligonucleotides via cationic lipoplexes and polyplexes

Journal of controlled release, 2011-07, Vol.153 (1), p.83-92

2011

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Retro-1-Oligonucleotide Conjugates. Synthesis and Biological Evaluation

Molecules (Basel, Switzerland), 2019-02, Vol.24 (3), p.579

2019

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Intracellular delivery of an antisense oligonucleotide via endocytosis of a G protein-coupled receptor

Nucleic acids research, 2010-10, Vol.38 (19), p.6567-6576

2010

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Aptamer-mediated delivery of splice-switching oligonucleotides to the nuclei of cancer cells

Nucleic acid therapeutics, 2012-06, Vol.22 (3), p.187-195

2012

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DNA Three-Way Junctions Stabilized by Hydrophobic Interactions for Creation of Functional Nanostructures

Chembiochem : a European journal of chemical biology, 2015-06, Vol.16 (9), p.1284-1287

2015

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Oligonucleotide Enhancing Compound Increases Tricyclo-DNA Mediated Exon-Skipping Efficacy in the Mdx Mouse Model

Cells (Basel, Switzerland), 2023-02, Vol.12 (5), p.702

2023

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DLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanisms

Molecular carcinogenesis, 2008-05, Vol.47 (5), p.326-337

2008

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Cell-targeting and cell-penetrating peptides for delivery of therapeutic and imaging agents

Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, 2009-05, Vol.1 (3), p.324-335

2009

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Regulation of anchorage-dependent signal transduction by protein kinase A and p21-activated kinase

Nature cell biology, 2000-09, Vol.2 (9), p.593-600

2000

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Targeted Intracellular Delivery of Antisense Oligonucleotides via Conjugation with Small-Molecule Ligands

Journal of the American Chemical Society, 2010-07, Vol.132 (26), p.8848-8849

2010

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A Molecular Umbrella Approach to the Intracellular Delivery of Small Interfering RNA

Bioconjugate chemistry, 2011-11, Vol.22 (11), p.2210-2216

2011

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Structure–activity relationships and cellular mechanism of action of small molecules that enhance the delivery of oligonucleotides

Nucleic acids research, 2018-02, Vol.46 (4), p.1601-1613

2018

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Impact of the Endosomal Escape Activity of Cell-Penetrating Peptides on the Endocytic Pathway

ACS chemical biology, 2020-09, Vol.15 (9), p.2355-2363

2020

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Antisense inhibition of P-glycoprotein expression using peptide–oligonucleotide conjugates

Biochemical pharmacology, 2000-07, Vol.60 (1), p.83-90

2000

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Tat-conjugated PAMAM dendrimers as delivery agents for antisense and siRNA oligonucleotides

Pharmaceutical research, 2005-12, Vol.22 (12), p.2099-2106

2005

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The small molecule Retro-1 enhances the pharmacological actions of antisense and splice switching oligonucleotides

Nucleic acids research, 2013-04, Vol.41 (6), p.3673-3687

2013

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Integrin-mediated signaling events in human endothelial cells

Molecular biology of the cell, 1998-08, Vol.9 (8), p.1969-1980

1998

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The delivery of therapeutic oligonucleotides

Cellular Uptake and Intracellular Trafficking of Antisense and siRNA Oligonucleotides

Chemical Manipulation of the Endosome Trafficking Machinery: Implications for Oligonucleotide Delivery

Addressing cancer signal transduction pathways with antisense and siRNA oligonucleotides

Enhanced delivery of peptide-morpholino oligonucleotides with a small molecule to correct splicing defects in the lung

Conditional Control of Alternative Splicing through Light-Triggered Splice-Switching Oligonucleotides

Cytosolic Delivery of Macromolecules in Live Human Cells Using the Combined Endosomal Escape Activities of a Small Molecule and Cell Penetrating Peptides

Multicellular Tumor Spheroids as a Model for Assessing Delivery of Oligonucleotides in Three Dimensions

Unconventional internalization mechanisms underlying functional delivery of antisense oligonucleotides via cationic lipoplexes and polyplexes

Retro-1-Oligonucleotide Conjugates. Synthesis and Biological Evaluation

Intracellular delivery of an antisense oligonucleotide via endocytosis of a G protein-coupled receptor

Aptamer-mediated delivery of splice-switching oligonucleotides to the nuclei of cancer cells

DNA Three-Way Junctions Stabilized by Hydrophobic Interactions for Creation of Functional Nanostructures

Oligonucleotide Enhancing Compound Increases Tricyclo-DNA Mediated Exon-Skipping Efficacy in the Mdx Mouse Model

DLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanisms

Cell-targeting and cell-penetrating peptides for delivery of therapeutic and imaging agents

Regulation of anchorage-dependent signal transduction by protein kinase A and p21-activated kinase

Targeted Intracellular Delivery of Antisense Oligonucleotides via Conjugation with Small-Molecule Ligands

A Molecular Umbrella Approach to the Intracellular Delivery of Small Interfering RNA

Structure–activity relationships and cellular mechanism of action of small molecules that enhance the delivery of oligonucleotides

Impact of the Endosomal Escape Activity of Cell-Penetrating Peptides on the Endocytic Pathway

Antisense inhibition of P-glycoprotein expression using peptide–oligonucleotide conjugates

Tat-conjugated PAMAM dendrimers as delivery agents for antisense and siRNA oligonucleotides

The small molecule Retro-1 enhances the pharmacological actions of antisense and splice switching oligonucleotides

Integrin-mediated signaling events in human endothelial cells

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