UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 39

Sortiert nach

Reaction Space Charting as a Tool in Organic Chemistry Research and Development

Advanced synthesis & catalysis, 2024-02, Vol.366 (4), p.551-573

2024

Volltextzugriff (PDF)

Synthesis, Biological Evaluation, and Molecular Modeling of Donepezil and N-[(5-(Benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine Hybrids as New Multipotent Cholinesterase/Monoamine Oxidase Inhibitors for the Treatment of Alzheimer’s Disease

Journal of medicinal chemistry, 2011-12, Vol.54 (24), p.8251-8270

2011

Volltextzugriff (PDF)

Lenalidomide Stabilizes Protein–Protein Complexes by Turning Labile Intermolecular H‑Bonds into Robust Interactions

Journal of medicinal chemistry, 2023-05, Vol.66 (9), p.6037-6046

2023

Volltextzugriff (PDF)

Synthesis and Multitarget Biological Profiling of a Novel Family of Rhein Derivatives As Disease-Modifying Anti-Alzheimer Agents

Journal of medicinal chemistry, 2014-03, Vol.57 (6), p.2549-2567

2014

Volltextzugriff (PDF)

Combining Virtual Reality Visualization with Ensemble Molecular Dynamics to Study Complex Protein Conformational Changes

Journal of chemical information and modeling, 2020-12, Vol.60 (12), p.6344-6354

2020

Volltextzugriff (PDF)

Unveiling a novel transient druggable pocket in BACE-1 through molecular simulations: Conformational analysis and binding mode of multisite inhibitors

PloS one, 2017-05, Vol.12 (5), p.e0177683

2017

Volltextzugriff (PDF)

Mechanism of the Pseudoirreversible Binding of Amantadine to the M2 Proton Channel

Journal of the American Chemical Society, 2016-11, Vol.138 (47), p.15345-15358

2016

Volltextzugriff (PDF)

Easily Accessible Polycyclic Amines that Inhibit the Wild-Type and Amantadine-Resistant Mutants of the M2 Channel of Influenza A Virus

Journal of medicinal chemistry, 2014-07, Vol.57 (13), p.5738-5747

2014

Volltextzugriff (PDF)

Impact of domain knowledge on blinded predictions of binding energies by alchemical free energy calculations

Journal of computer-aided molecular design, 2018-01, Vol.32 (1), p.199-210

2018

Volltextzugriff (PDF)

Dynamic design: manipulation of millisecond timescale motions on the energy landscape of cyclophilin A

Chemical science (Cambridge), 2020-03, Vol.11 (1), p.267-268

2020

Volltextzugriff (PDF)

Exploring the Size Limit of Templates for Inhibitors of the M2 Ion Channel of Influenza A Virus

Journal of medicinal chemistry, 2011-04, Vol.54 (8), p.2646-2657

2011

Volltextzugriff (PDF)

Assessing the Suitability of the Multilevel Strategy for the Conformational Analysis of Small Ligands

The journal of physical chemistry. B, 2015-01, Vol.119 (3), p.1164-1172

2015

Volltextzugriff (PDF)

A versatile luminescent probe for sensing and monitoring amyloid proteins

Dyes and pigments, 2024-12, Vol.231, p.112348, Article 112348

2024

Volltextzugriff (PDF)

Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer’s Disease

Journal of medicinal chemistry, 2022-03, Vol.65 (6), p.4909-4925

2022

Volltextzugriff (PDF)

Dual Effect of Prussian Blue Nanoparticles on Aβ40 Aggregation: β‑Sheet Fibril Reduction and Copper Dyshomeostasis Regulation

Biomacromolecules, 2021-02, Vol.22 (2), p.430-440

2021

Volltextzugriff (PDF)

Blinded predictions of binding modes and energies of HSP90-α ligands for the 2015 D3R grand challenge

Bioorganic & medicinal chemistry, 2016-10, Vol.24 (20), p.4890-4899

2016

Volltextzugriff (PDF)

The complex of hypericin with β-lactoglobulin has antimicrobial activity with potential applications in dairy industry

Journal of dairy science, 2015-01, Vol.98 (1), p.89-94

2015

Volltextzugriff (PDF)

Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies

European journal of medicinal chemistry, 2014-09, Vol.84, p.107-117

2014

Volltextzugriff (PDF)

A computationally designed binding mode flip leads to a novel class of potent tri-vector cyclophilin inhibitors

Chemical science (Cambridge), 2019-01, Vol.10 (2), p.542-547

2019

Volltextzugriff (PDF)

Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors

Bioorganic & medicinal chemistry, 2016-10, Vol.24 (20), p.4835-4854

2016

Volltextzugriff (PDF)

Tetrahydrobenzothiophene carboxamides: Beyond the kinase domain and into the fatty acid realm

Bioorganic & medicinal chemistry letters, 2017-09, Vol.27 (18), p.4462-4466

2017

Volltextzugriff (PDF)

Correction: Unveiling a novel transient druggable pocket in BACE-1 through molecular simulations: Conformational analysis and binding mode of multisite inhibitors

PloS one, 2017-12, Vol.12 (12), p.e0190327-e0190327

2017

Volltextzugriff (PDF)

Unveiling a Novel Transient Druggable Pocket in BACE-1 through Molecular Simulations: Conformational Analysis and Binding Mode of Multisite Inhibitors

PloS one, 2017-12

2017

Volltextzugriff (PDF)

First homology model of Plasmodium falciparum glucose-6-phosphate dehydrogenase: Discovery of selective substrate analog-based inhibitors as novel antimalarial agents

European journal of medicinal chemistry, 2018-02, Vol.146, p.108-122

2018

Volltextzugriff (PDF)

1,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: Synthesis, pharmacological evaluation and mechanistic studies

European journal of medicinal chemistry, 2014-02, Vol.73, p.141-152

2014

Volltextzugriff (PDF)

1 – 25 von 39

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(39)
Mit Volltextzugriff
(39)

Publikationsform

Artikel
(39)

Sprache

Englisch
(38)
Japanisch
(5)

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 90 Tagen
(1)

Menü

Weitere Dienste

Einstellungen

Reaction Space Charting as a Tool in Organic Chemistry Research and Development

Synthesis, Biological Evaluation, and Molecular Modeling of Donepezil and N-[(5-(Benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine Hybrids as New Multipotent Cholinesterase/Monoamine Oxidase Inhibitors for the Treatment of Alzheimer’s Disease

Lenalidomide Stabilizes Protein–Protein Complexes by Turning Labile Intermolecular H‑Bonds into Robust Interactions

Synthesis and Multitarget Biological Profiling of a Novel Family of Rhein Derivatives As Disease-Modifying Anti-Alzheimer Agents

Combining Virtual Reality Visualization with Ensemble Molecular Dynamics to Study Complex Protein Conformational Changes

Unveiling a novel transient druggable pocket in BACE-1 through molecular simulations: Conformational analysis and binding mode of multisite inhibitors

Mechanism of the Pseudoirreversible Binding of Amantadine to the M2 Proton Channel

Easily Accessible Polycyclic Amines that Inhibit the Wild-Type and Amantadine-Resistant Mutants of the M2 Channel of Influenza A Virus

Impact of domain knowledge on blinded predictions of binding energies by alchemical free energy calculations

Dynamic design: manipulation of millisecond timescale motions on the energy landscape of cyclophilin A

Exploring the Size Limit of Templates for Inhibitors of the M2 Ion Channel of Influenza A Virus

Assessing the Suitability of the Multilevel Strategy for the Conformational Analysis of Small Ligands

A versatile luminescent probe for sensing and monitoring amyloid proteins

Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer’s Disease

Dual Effect of Prussian Blue Nanoparticles on Aβ40 Aggregation: β‑Sheet Fibril Reduction and Copper Dyshomeostasis Regulation

Blinded predictions of binding modes and energies of HSP90-α ligands for the 2015 D3R grand challenge

The complex of hypericin with β-lactoglobulin has antimicrobial activity with potential applications in dairy industry

Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies

A computationally designed binding mode flip leads to a novel class of potent tri-vector cyclophilin inhibitors

Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors

Tetrahydrobenzothiophene carboxamides: Beyond the kinase domain and into the fatty acid realm

Correction: Unveiling a novel transient druggable pocket in BACE-1 through molecular simulations: Conformational analysis and binding mode of multisite inhibitors

Unveiling a Novel Transient Druggable Pocket in BACE-1 through Molecular Simulations: Conformational Analysis and Binding Mode of Multisite Inhibitors

First homology model of Plasmodium falciparum glucose-6-phosphate dehydrogenase: Discovery of selective substrate analog-based inhibitors as novel antimalarial agents

1,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: Synthesis, pharmacological evaluation and mechanistic studies

Suchergebnisse filtern