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The biophysics and cell biology of lipid droplets

Nature reviews. Molecular cell biology, 2013-12, Vol.14 (12), p.775

2013

Volltextzugriff (PDF)

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

Nature (London), 2010-03, Vol.464 (7285), p.121-125

2010

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DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes[S]

Journal of lipid research, 2011-04, Vol.52 (4), p.657-667

2011

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Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice

Journal of lipid research, 2008-09, Vol.49 (9), p.2038-2044

2008

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The Endoplasmic Reticulum Enzyme DGAT2 Is Found in Mitochondria-associated Membranes and Has a Mitochondrial Targeting Signal That Promotes Its Association with Mitochondria

The Journal of biological chemistry, 2009-02, Vol.284 (8), p.5352-5361

2009

Volltextzugriff (PDF)

Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting

eLife, 2014-02, Vol.3, p.e01607

2014

Volltextzugriff (PDF)

Membrane Topology and Identification of Key Functional Amino Acid Residues of Murine Acyl-CoA:Diacylglycerol Acyltransferase-2

The Journal of biological chemistry, 2006-12, Vol.281 (52), p.40273-40282

2006

Volltextzugriff (PDF)

Angiopoietin-like 4 (ANGPTL4, Fasting-induced Adipose Factor) Is a Direct Glucocorticoid Receptor Target and Participates in Glucocorticoid-regulated Triglyceride Metabolism

The Journal of biological chemistry, 2009-09, Vol.284 (38), p.25593-25601

2009

Volltextzugriff (PDF)

Lipid droplets and liver disease: from basic biology to clinical implications

Nature reviews. Gastroenterology & hepatology, 2017-06, Vol.14 (6), p.343

2017

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Short-term overexpression of DGAT1 or DGAT2 increases hepatic triglyceride but not VLDL triglyceride or apoB production

Journal of lipid research, 2006-10, Vol.47 (10), p.2297-2305

2006

Volltextzugriff (PDF)

triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters

Journal of lipid research, 2005-07, Vol.46 (7), p.1502-1511

2005

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Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury

The Journal of clinical investigation, 2022-01, Vol.132 (1), p.1-1

2022

Volltextzugriff (PDF)

Dissociation of Obesity and Impaired Glucose Disposal in Mice Overexpressing Acyl Coenzyme A:Diacylglycerol Acyltransferase 1 in White Adipose Tissue

Diabetes (New York, N.Y.), 2002-11, Vol.51 (11), p.3189-3195

2002

Volltextzugriff (PDF)

neurodegenerative disease mutation that accelerates the clearance of apoptotic cells

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (11), p.4441-4446

2011

Volltextzugriff (PDF)

The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes

Journal of lipid research, 2019-06, Vol.60 (6), p.1112-1120

2019

Volltextzugriff (PDF)

Lipid droplet biogenesis

Current opinion in cell biology, 2014-08, Vol.29, p.39-45

2014

Volltextzugriff (PDF)

Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme

Nature (London), 2020-05, Vol.581 (7808), p.323-328

2020

Volltextzugriff (PDF)

Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin

The Journal of biological chemistry, 2009-02, Vol.284 (7), p.4292-4299

2009

Volltextzugriff (PDF)

Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis

Cell reports (Cambridge), 2020-11, Vol.33 (5), p.108348-108348, Article 108348

2020

Volltextzugriff (PDF)

Lipid droplets at a glance

Journal of cell science, 2009-03, Vol.122 (6), p.749-752

2009

Volltextzugriff (PDF)

Role of Adipocyte-Derived Factors in Enhancing Insulin Signaling in Skeletal Muscle and White Adipose Tissue of Mice Lacking Acyl CoA:Diacylglycerol Acyltransferase 1

Diabetes (New York, N.Y.), 2004-06, Vol.53 (6), p.1445-1451

2004

Volltextzugriff (PDF)

Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models

Nature medicine, 2014-10, Vol.20 (10), p.1157-1164

2014

Volltextzugriff (PDF)

Structure and function of lipid droplet assembly complexes

Current opinion in structural biology, 2023-06, Vol.80, p.102606-102606, Article 102606

2023

Volltextzugriff (PDF)

Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1

Nature medicine, 2010-11, Vol.16 (11), p.1295-1298

2010

Volltextzugriff (PDF)

Determination of adipocyte size by computer image analysis

Journal of lipid research, 2002-06, Vol.43 (6), p.986-989

2002

Volltextzugriff (PDF)

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The biophysics and cell biology of lipid droplets

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes[S]

Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice

The Endoplasmic Reticulum Enzyme DGAT2 Is Found in Mitochondria-associated Membranes and Has a Mitochondrial Targeting Signal That Promotes Its Association with Mitochondria

Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting

Membrane Topology and Identification of Key Functional Amino Acid Residues of Murine Acyl-CoA:Diacylglycerol Acyltransferase-2

Angiopoietin-like 4 (ANGPTL4, Fasting-induced Adipose Factor) Is a Direct Glucocorticoid Receptor Target and Participates in Glucocorticoid-regulated Triglyceride Metabolism

Lipid droplets and liver disease: from basic biology to clinical implications

Short-term overexpression of DGAT1 or DGAT2 increases hepatic triglyceride but not VLDL triglyceride or apoB production

triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters

Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury

Dissociation of Obesity and Impaired Glucose Disposal in Mice Overexpressing Acyl Coenzyme A:Diacylglycerol Acyltransferase 1 in White Adipose Tissue

neurodegenerative disease mutation that accelerates the clearance of apoptotic cells

The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes

Lipid droplet biogenesis

Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme

Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin

Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis

Lipid droplets at a glance

Role of Adipocyte-Derived Factors in Enhancing Insulin Signaling in Skeletal Muscle and White Adipose Tissue of Mice Lacking Acyl CoA:Diacylglycerol Acyltransferase 1

Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models

Structure and function of lipid droplet assembly complexes

Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1

Determination of adipocyte size by computer image analysis

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