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Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis

Nature medicine, 2009-09, Vol.15 (9), p.1055-1061

2009

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Noncanonical hedgehog pathway activation through SRF–MKL1 promotes drug resistance in basal cell carcinomas

Nature medicine, 2018-03, Vol.24 (3), p.271-281

2018

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First-in-human trial of nanoelectroablation therapy for basal cell carcinoma: proof of method

Experimental dermatology, 2014-02, Vol.23 (2), p.135-137

2014

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Inhibition of smoothened signaling prevents ultraviolet B-induced basal cell carcinomas through regulation of Fas expression and apoptosis

Cancer research (Chicago, Ill.), 2004-10, Vol.64 (20), p.7545-7552

2004

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Basal Cell Carcinomas in Mice Overexpressing Sonic Hedgehog

Science (American Association for the Advancement of Science), 1997-05, Vol.276 (5313), p.817-821

1997

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Pharmacologic retinoid signaling and physiologic retinoic acid receptor signaling inhibit basal cell carcinoma tumorigenesis

Molecular cancer therapeutics, 2008-05, Vol.7 (5), p.1275-1284

2008

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Human Homolog of patched, a Candidate Gene for the Basal Cell Nevus Syndrome

Science (American Association for the Advancement of Science), 1996-06, Vol.272 (5268), p.1668-1671

1996

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Topical Thymidine Dinucleotide Treatment Reduces Development of Ultraviolet-Induced Basal Cell Carcinoma in Ptch-1+/− Mice

The American journal of pathology, 2008-05, Vol.172 (5), p.1248-1255

2008

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Inhibiting the Hedgehog Pathway in Patients with the Basal-Cell Nevus Syndrome

The New England journal of medicine, 2012-06, Vol.366 (23), p.2180-2188

2012

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Long-term establishment, characterization and manipulation of cell lines from mouse basal cell carcinoma tumors

Experimental dermatology, 2006-09, Vol.15 (9), p.742-750

2006

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Itraconazole and Arsenic Trioxide Inhibit Hedgehog Pathway Activation and Tumor Growth Associated with Acquired Resistance to Smoothened Antagonists

Cancer cell, 2013-01, Vol.23 (1), p.23-34

2013

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Basal Cell Carcinomas Arise from Hair Follicle Stem Cells in Ptch1 +/− Mice

Cancer cell, 2011-01, Vol.19 (1), p.114-124

2011

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Topical tazarotene chemoprevention reduces Basal cell carcinoma number and size in Ptch1+/- mice exposed to ultraviolet or ionizing radiation

Cancer research (Chicago, Ill.), 2004-07, Vol.64 (13), p.4385-4389

2004

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Elevated Cutaneous Smad Activation Associates with Enhanced Skin Tumor Susceptibility in Organ Transplant Recipients

Clinical cancer research, 2009-08, Vol.15 (16), p.5101-5107

2009

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Inhibition of the hedgehog pathway in patients with basal-cell nevus syndrome: final results from the multicentre, randomised, double-blind, placebo-controlled, phase 2 trial

The lancet oncology, 2016-12, Vol.17 (12), p.1720-1731

2016

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CUSP/p63 expression in basal cell carcinoma

Experimental dermatology, 2002-06, Vol.11 (3), p.203-208

2002

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Posaconazole, a Second-Generation Triazole Antifungal Drug, Inhibits the Hedgehog Signaling Pathway and Progression of Basal Cell Carcinoma

Molecular cancer therapeutics, 2016-05, Vol.15 (5), p.866-876

2016

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Genomic Stability in Syndromic Basal Cell Carcinoma

Journal of investigative dermatology, 2018-05, Vol.138 (5), p.1044-1051

2018

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Vitamin D 3 Produced by Skin Exposure to UVR Inhibits Murine Basal Cell Carcinoma Carcinogenesis

Journal of investigative dermatology, 2017-12, Vol.137 (12), p.2613

2017

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An Anchor for Tumor Cell Invasion

Science (American Association for the Advancement of Science), 2005-03, Vol.307 (5716), p.1727-1728

2005

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Vitamin D3 inhibits hedgehog signaling and proliferation in murine Basal cell carcinomas

Cancer prevention research (Philadelphia, Pa.), 2011-05, Vol.4 (5), p.744-751

2011

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Mommy - where do tumors come from?

The Journal of clinical investigation, 2011-05, Vol.121 (5), p.1681-1683

Epstein, Jr, Ervin H

2011

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Effect of Calcium Channel Blockade on Vismodegib-Induced Muscle Cramps

JAMA dermatology (Chicago, Ill.), 2015-10, Vol.151 (10), p.1132

2015

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Basal cell carcinoma—pay your money, take your choice

Nature reviews. Clinical oncology, 2013-09, Vol.10 (9), p.489-490

Epstein, Ervin H.

2013

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The use of vismodegib to shrink keratocystic odontogenic tumors in patients with basal cell nevus syndrome

JAMA dermatology (Chicago, Ill.), 2014-05, Vol.150 (5), p.542

2014

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Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis

Noncanonical hedgehog pathway activation through SRF–MKL1 promotes drug resistance in basal cell carcinomas

First-in-human trial of nanoelectroablation therapy for basal cell carcinoma: proof of method

Inhibition of smoothened signaling prevents ultraviolet B-induced basal cell carcinomas through regulation of Fas expression and apoptosis

Basal Cell Carcinomas in Mice Overexpressing Sonic Hedgehog

Pharmacologic retinoid signaling and physiologic retinoic acid receptor signaling inhibit basal cell carcinoma tumorigenesis

Human Homolog of patched, a Candidate Gene for the Basal Cell Nevus Syndrome

Topical Thymidine Dinucleotide Treatment Reduces Development of Ultraviolet-Induced Basal Cell Carcinoma in Ptch-1+/− Mice

Inhibiting the Hedgehog Pathway in Patients with the Basal-Cell Nevus Syndrome

Long-term establishment, characterization and manipulation of cell lines from mouse basal cell carcinoma tumors

Itraconazole and Arsenic Trioxide Inhibit Hedgehog Pathway Activation and Tumor Growth Associated with Acquired Resistance to Smoothened Antagonists

Basal Cell Carcinomas Arise from Hair Follicle Stem Cells in Ptch1 +/− Mice

Topical tazarotene chemoprevention reduces Basal cell carcinoma number and size in Ptch1+/- mice exposed to ultraviolet or ionizing radiation

Elevated Cutaneous Smad Activation Associates with Enhanced Skin Tumor Susceptibility in Organ Transplant Recipients

Inhibition of the hedgehog pathway in patients with basal-cell nevus syndrome: final results from the multicentre, randomised, double-blind, placebo-controlled, phase 2 trial

CUSP/p63 expression in basal cell carcinoma

Posaconazole, a Second-Generation Triazole Antifungal Drug, Inhibits the Hedgehog Signaling Pathway and Progression of Basal Cell Carcinoma

Genomic Stability in Syndromic Basal Cell Carcinoma

Vitamin D 3 Produced by Skin Exposure to UVR Inhibits Murine Basal Cell Carcinoma Carcinogenesis

An Anchor for Tumor Cell Invasion

Vitamin D3 inhibits hedgehog signaling and proliferation in murine Basal cell carcinomas

Mommy - where do tumors come from?

Effect of Calcium Channel Blockade on Vismodegib-Induced Muscle Cramps

Basal cell carcinoma—pay your money, take your choice

The use of vismodegib to shrink keratocystic odontogenic tumors in patients with basal cell nevus syndrome

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