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Protective effect of quercetin on high-fat diet-induced non-alcoholic fatty liver disease in mice is mediated by modulating intestinal microbiota imbalance and related gut-liver axis activation

Free radical biology & medicine, 2017-01, Vol.102, p.188-202

2017

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Molecular mechanisms of hepatotoxic cholestasis by clavulanic acid: Role of NRF2 and FXR pathways

Food and chemical toxicology, 2021-12, Vol.158, p.112664-112664, Article 112664

2021

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Functional Interactions between Gut Microbiota Transplantation, Quercetin, and High‐Fat Diet Determine Non‐Alcoholic Fatty Liver Disease Development in Germ‐Free Mice

Molecular nutrition & food research, 2019-04, Vol.63 (8), p.e1800930-n/a

2019

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Exploring Individual Variability in Drug-Induced Liver Injury (DILI) Responses through Metabolomic Analysis

International journal of molecular sciences, 2024-03, Vol.25 (5), p.3003

2024

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Hepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells

World journal of gastroenterology : WJG, 2006-09, Vol.12 (36), p.5834

2006

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Valproate and Short-Chain Fatty Acids Activate Transcription of the Human Vitamin D Receptor Gene through a Proximal GC-Rich DNA Region Containing Two Putative Sp1 Binding Sites

Nutrients, 2022-06, Vol.14 (13), p.2673

2022

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The Synbiotic Combination of Akkermansia muciniphila and Quercetin Ameliorates Early Obesity and NAFLD through Gut Microbiota Reshaping and Bile Acid Metabolism Modulation

Antioxidants, 2021-12, Vol.10 (12), p.2001

2021

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Human Upcyte Hepatocytes: Characterization of the Hepatic Phenotype and Evaluation for Acute and Long-Term Hepatotoxicity Routine Testing

Toxicological sciences, 2016-07, Vol.152 (1), p.214-229

2016

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Drug-Induced Fatty Liver Disease (DIFLD): A Comprehensive Analysis of Clinical, Biochemical, and Histopathological Data for Mechanisms Identification and Consistency with Current Adverse Outcome Pathways

International journal of molecular sciences, 2024-05, Vol.25 (10), p.5203

2024

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Epistane, an anabolic steroid used for recreational purposes, causes cholestasis with elevated levels of cholic acid conjugates, by upregulating bile acid synthesis (CYP8B1) and cross-talking with nuclear receptors in human hepatocytes

Archives of toxicology, 2020-02, Vol.94 (2), p.589-607

2020

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Advantageous use of HepaRG cells for the screening and mechanistic study of drug-induced steatosis

Toxicology and applied pharmacology, 2016-07, Vol.302, p.1-9

2016

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Corrigendum to “Novel clinical phenotypes, drug categorization, and outcome prediction in drug-induced cholestasis: Analysis of a database of 432 patients developed by literature review and machine learning support” [Biomed. Pharmacother. 174 (2024) 116530]

Biomedicine & pharmacotherapy, 2024-06, Vol.175, p.116813, Article 116813

2024

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Novel clinical phenotypes, drug categorization, and outcome prediction in drug-induced cholestasis: Analysis of a database of 432 patients developed by literature review and machine learning support

Biomedicine & pharmacotherapy, 2024-05, Vol.174, p.116530-116530, Article 116530

2024

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Quantitative Prediction of Steatosis in Patients with Non-Alcoholic Fatty Liver by Means of Hepatic MicroRNAs Present in Serum and Correlating with Hepatic Fat

International journal of molecular sciences, 2022-08, Vol.23 (16), p.9298

2022

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Idiosyncratic Drug-Induced Liver Injury and Amoxicillin-Clavulanate: Spotlight on Gut Microbiota, Fecal Metabolome and Bile Acid Profile in Patients

International journal of molecular sciences, 2024-07, Vol.25 (13), p.6863

2024

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Foxa1 reduces lipid accumulation in human hepatocytes and is down-regulated in nonalcoholic fatty liver

PloS one, 2012-01, Vol.7 (1), p.e30014-e30014

2012

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Gut Microbiota and Plasma Bile Acids Associated with Non-Alcoholic Fatty Liver Disease Resolution in Bariatric Surgery Patients

Nutrients, 2023-07, Vol.15 (14), p.3187

2023

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Hepatic cell lines for drug hepatotoxicity testing: limitations and strategies to upgrade their metabolic competence by gene engineering

Current drug metabolism, 2013-11, Vol.14 (9), p.946-968

2013

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The Vitamin D Receptor Regulates Glycerolipid and Phospholipid Metabolism in Human Hepatocytes

Biomolecules (Basel, Switzerland), 2020-03, Vol.10 (3), p.493

2020

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Elimination of Vitamin D Signaling Causes Increased Mortality in a Model of Overactivation of the Insulin Receptor: Role of Lipid Metabolism

Nutrients, 2022-04, Vol.14 (7), p.1516

2022

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PTEN Deletion in Adult Mice Induces Hypoinsulinemia With Concomitant Low Glucose Levels

Frontiers in endocrinology (Lausanne), 2022-02, Vol.13, p.850214-850214

2022

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Transcriptional regulation of cytochrome p450 genes by the nuclear receptor hepatocyte nuclear factor 4-alpha

Current drug metabolism, 2009-06, Vol.10 (5), p.508-519

2009

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The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes

Communications biology, 2022-08, Vol.5 (1), p.827-827, Article 827

2022

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Down‐regulation of human CYP3A4 by the inflammatory signal interleukin 6: molecular mechanism and transcription factors involved

The FASEB journal, 2002-11, Vol.16 (13), p.1-29

2002

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Protective effect of quercetin on high-fat diet-induced non-alcoholic fatty liver disease in mice is mediated by modulating intestinal microbiota imbalance and related gut-liver axis activation

Molecular mechanisms of hepatotoxic cholestasis by clavulanic acid: Role of NRF2 and FXR pathways

Functional Interactions between Gut Microbiota Transplantation, Quercetin, and High‐Fat Diet Determine Non‐Alcoholic Fatty Liver Disease Development in Germ‐Free Mice

Exploring Individual Variability in Drug-Induced Liver Injury (DILI) Responses through Metabolomic Analysis

Hepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells

Valproate and Short-Chain Fatty Acids Activate Transcription of the Human Vitamin D Receptor Gene through a Proximal GC-Rich DNA Region Containing Two Putative Sp1 Binding Sites

The Synbiotic Combination of Akkermansia muciniphila and Quercetin Ameliorates Early Obesity and NAFLD through Gut Microbiota Reshaping and Bile Acid Metabolism Modulation

Human Upcyte Hepatocytes: Characterization of the Hepatic Phenotype and Evaluation for Acute and Long-Term Hepatotoxicity Routine Testing

Drug-Induced Fatty Liver Disease (DIFLD): A Comprehensive Analysis of Clinical, Biochemical, and Histopathological Data for Mechanisms Identification and Consistency with Current Adverse Outcome Pathways

Epistane, an anabolic steroid used for recreational purposes, causes cholestasis with elevated levels of cholic acid conjugates, by upregulating bile acid synthesis (CYP8B1) and cross-talking with nuclear receptors in human hepatocytes

Advantageous use of HepaRG cells for the screening and mechanistic study of drug-induced steatosis

Restoring cellular magnesium balance through Cyclin M4 protects against acetaminophen-induced liver damage

Corrigendum to “Novel clinical phenotypes, drug categorization, and outcome prediction in drug-induced cholestasis: Analysis of a database of 432 patients developed by literature review and machine learning support” [Biomed. Pharmacother. 174 (2024) 116530]

Novel clinical phenotypes, drug categorization, and outcome prediction in drug-induced cholestasis: Analysis of a database of 432 patients developed by literature review and machine learning support

Quantitative Prediction of Steatosis in Patients with Non-Alcoholic Fatty Liver by Means of Hepatic MicroRNAs Present in Serum and Correlating with Hepatic Fat

Idiosyncratic Drug-Induced Liver Injury and Amoxicillin-Clavulanate: Spotlight on Gut Microbiota, Fecal Metabolome and Bile Acid Profile in Patients

Foxa1 reduces lipid accumulation in human hepatocytes and is down-regulated in nonalcoholic fatty liver

Gut Microbiota and Plasma Bile Acids Associated with Non-Alcoholic Fatty Liver Disease Resolution in Bariatric Surgery Patients

Hepatic cell lines for drug hepatotoxicity testing: limitations and strategies to upgrade their metabolic competence by gene engineering

The Vitamin D Receptor Regulates Glycerolipid and Phospholipid Metabolism in Human Hepatocytes

Elimination of Vitamin D Signaling Causes Increased Mortality in a Model of Overactivation of the Insulin Receptor: Role of Lipid Metabolism

PTEN Deletion in Adult Mice Induces Hypoinsulinemia With Concomitant Low Glucose Levels

Transcriptional regulation of cytochrome p450 genes by the nuclear receptor hepatocyte nuclear factor 4-alpha

The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes

Down‐regulation of human CYP3A4 by the inflammatory signal interleukin 6: molecular mechanism and transcription factors involved

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