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A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response

Cell, 2016-12, Vol.167 (7), p.1867-1882.e21

2016

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Exploring genetic interaction manifolds constructed from rich single-cell phenotypes

Science (American Association for the Advancement of Science), 2019-08, Vol.365 (6455), p.786-793

2019

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Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs

Nature biotechnology, 2020-03, Vol.38 (3), p.355-364

2020

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GIGYF2 and 4EHP Inhibit Translation Initiation of Defective Messenger RNAs to Assist Ribosome-Associated Quality Control

Molecular cell, 2020-09, Vol.79 (6), p.950-962.e6

2020

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Structure of the Catalytic Domain of the Class I Polyhydroxybutyrate Synthase from Cupriavidus necator

The Journal of biological chemistry, 2016-11, Vol.291 (48), p.25264-25277

2016

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The Transcription Factor CarH Safeguards Use of Adenosylcobalamin as a Light Sensor by Altering the Photolysis Products

Biochemistry (Easton), 2015-06, Vol.54 (21), p.3231-3234

2015

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Structural basis for gene regulation by a B12-dependent photoreceptor

Nature (London), 2015-09, Vol.526 (7574), p.536-541

2015

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Arteriogenesis depends on circulating monocytes and macrophage accumulation and is severely depressed in op/op mice

Journal of leukocyte biology, 2006-07, Vol.80 (1), p.59-65

2006

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Handbuch HärtereiPraxis

3, 2021

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Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells

eLife, 2021-05, Vol.10

2021

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Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors

eLife, 2022-12, Vol.11

2022

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CRISPR-based functional genomics in human dendritic cells

eLife, 2021-04, Vol.10

2021

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Visualization of a radical B₁₂ enzyme with its G-protein chaperone

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (8), p.2419-2424

2015

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Metal Binding Properties of Escherichia coli YjiA, a Member of the Metal Homeostasis-Associated COG0523 Family of GTPases

Biochemistry (Easton), 2013-03, Vol.52 (10), p.1788-1801

2013

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Structure of Adenovirus Type 21 Knob in Complex with CD46 Reveals Key Differences in Receptor Contacts among Species B Adenoviruses

Journal of Virology, 2010-04, Vol.84 (7), p.3189-3200

2010

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In vivo profiling of DPP4 inhibitors reveals alterations in collagen metabolism and accumulation of an amyloid peptide in rat plasma

Biochemical pharmacology, 2009-01, Vol.77 (2), p.228-237

2009

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CRISPR Approaches to Small Molecule Target Identification

ACS chemical biology, 2018-02, Vol.13 (2), p.366-375

2018

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A New Facet of Vitamin B 12 : Gene Regulation by Cobalamin-Based Photoreceptors

Annual review of biochemistry, 2017-06, Vol.86, p.485

2017

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Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq

Cell, 2022-07, Vol.185 (14), p.2559-2575.e28

2022

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Molecular recording of mammalian embryogenesis

Nature (London), 2019-06, Vol.570 (7759), p.77-82

2019

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Electrochemical characterization of Escherichia coli adaptive response protein AidB

International journal of molecular sciences, 2012-12, Vol.13 (12), p.16899-16915

2012

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Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent

Molecular cell, 2017-10, Vol.68 (1), p.210-223.e6

2017

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Surrogate end points: how well do they represent patient-relevant end points?

Biomarkers in medicine, 2007-10, Vol.1 (3), p.437-451

Jost, Marco M

2007

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The concept of functional peptidomics for the discovery of bioactive peptides in cell culture models

Combinatorial chemistry & high throughput screening, 2005-12, Vol.8 (8), p.767

2005

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DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro

Nucleic acids research, 2019-06, Vol.47 (11), p.5522

2019

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A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response

Exploring genetic interaction manifolds constructed from rich single-cell phenotypes

Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs

GIGYF2 and 4EHP Inhibit Translation Initiation of Defective Messenger RNAs to Assist Ribosome-Associated Quality Control

Structure of the Catalytic Domain of the Class I Polyhydroxybutyrate Synthase from Cupriavidus necator

The Transcription Factor CarH Safeguards Use of Adenosylcobalamin as a Light Sensor by Altering the Photolysis Products

Structural basis for gene regulation by a B12-dependent photoreceptor

Arteriogenesis depends on circulating monocytes and macrophage accumulation and is severely depressed in op/op mice

Handbuch HärtereiPraxis

Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells

Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors

CRISPR-based functional genomics in human dendritic cells

Visualization of a radical B₁₂ enzyme with its G-protein chaperone

Metal Binding Properties of Escherichia coli YjiA, a Member of the Metal Homeostasis-Associated COG0523 Family of GTPases

Structure of Adenovirus Type 21 Knob in Complex with CD46 Reveals Key Differences in Receptor Contacts among Species B Adenoviruses

In vivo profiling of DPP4 inhibitors reveals alterations in collagen metabolism and accumulation of an amyloid peptide in rat plasma

CRISPR Approaches to Small Molecule Target Identification

A New Facet of Vitamin B 12 : Gene Regulation by Cobalamin-Based Photoreceptors

Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq

Molecular recording of mammalian embryogenesis

Electrochemical characterization of Escherichia coli adaptive response protein AidB

Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent

Surrogate end points: how well do they represent patient-relevant end points?

The concept of functional peptidomics for the discovery of bioactive peptides in cell culture models

DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro

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