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Experimental models in Chagas disease: a review of the methodologies applied for screening compounds against Trypanosoma cruzi

Parasitology research (1987), 2018-11, Vol.117 (11), p.3367-3380

2018

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Development of novel benznidazole formulations: Physicochemical characterization and in vivo evaluation on parasitemia reduction in Chagas disease

International journal of pharmaceutics, 2014-09, Vol.472 (1-2), p.110-117

2014

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5-Nitroindazole-based compounds: further studies for activity optimization as anti-Trypanosoma cruzi agents

Acta tropica, 2022-10, Vol.234, p.106607-106607, Article 106607

2022

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Selective activity of 2,4-diaryl-1,2,3,4-tetrahydroquinolines on Trypanosoma cruzi epimastigotes and amastigotes expressing β-galactosidase

Bioorganic & medicinal chemistry letters, 2013-09, Vol.23 (17), p.4851-4856

2013

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Development of resazurin microtiter assay for drug sensibility testing of Trypanosoma cruzi epimastigotes

Parasitology research (1987), 2006-07, Vol.99 (2), p.103-107

2006

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Novel solid dispersions of benznidazole: Preparation, dissolution profile and biological evaluation as alternative antichagasic drug delivery system

Experimental parasitology, 2015-02, Vol.149, p.84-91

2015

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Novel Imidazo[4,5-c][1,2,6]thiadiazine 2,2-dioxides as antiproliferative trypanosoma cruzi drugs: Computational screening from neural network, synthesis and in vivo biological properties

European journal of medicinal chemistry, 2017-08, Vol.136, p.223-234

2017

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Bond-based bilinear indices for computational discovery of novel trypanosomicidal drug-like compounds through virtual screening

European journal of medicinal chemistry, 2015-05, Vol.96, p.238-244

2015

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Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes

Parasitology, 2016-09, Vol.143 (11), p.1469-1478

2016

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Drug repositioning for novel antitrichomonas from known antiprotozoan drugs using hierarchical screening

Future medicinal chemistry, 2018-04, Vol.10 (8), p.863-878

2018

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Selective activity of polyene macrolides produced by genetically modified Streptomyces on Trypanosoma cruzi

International journal of antimicrobial agents, 2006-08, Vol.28 (2), p.104-109

2006

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Ligand-based discovery of novel trypanosomicidal drug-like compounds: In silico identification and experimental support

European journal of medicinal chemistry, 2011-08, Vol.46 (8), p.3324-3330

2011

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Identification In Silico and In Vitro of Novel Trypanosomicidal Drug-Like Compounds

Chemical biology & drug design, 2012-07, Vol.80 (1), p.38-45

2012

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Activity profile of two 5-nitroindazole derivatives over the moderately drug-resistant Trypanosoma cruzi Y strain (DTU TcII): in vitro and in vivo studies

Parasitology, 2020-09, Vol.147 (11), p.1216-1228

2020

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Saponinas esteroidales de la planta Agave brittoniana (Agavaceae) con actividad contra el parásito Trichomona vaginalis

Revista de biología tropical, 2008-12, Vol.56 (4), p.1645-1652

2008

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Biological Characterization of Trypanosoma cruzi Strains

Memórias do Instituto Oswaldo Cruz, 2001-01, Vol.96 (1), p.53-59

2001

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Antiparasitic properties of homoallylamines and related compounds

Acta parasitologica, 2006-03, Vol.51 (1), p.73-78

2006

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Biological variability in clinical isolates of Trichomonas vaginalis

Memórias do Instituto Oswaldo Cruz, 2002-09, Vol.97 (6), p.893-896

2002

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Relationship between biological behaviour and randomly amplified polymorphic DNA profiles of Trypanosoma cruzi strains

Memórias do Instituto Oswaldo Cruz, 2001-02, Vol.96 (2), p.251-256

2001

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Steroidal saponins from the plant Agave brittoniana with activity against the parasite Trichomona vaginalis

Revista de biología tropical, 2008-12, Vol.56 (4), p.1645-1652

2008

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Exploring the potential activity spectrum of two 5-nitroindazolinone prototypes on different Trypanosoma cruzi strains

Parasitology open, 2015, Vol.1, Article e1

2015

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Saponinas esteroidales de la planta Agave brittoniana (Agavaceae) con actividad contra el parásito Trichomona vaginalis

Revista de biología tropical, 2008-12, Vol.56 (4), p.1645-1652

2008

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Saponinas esteroidales de la planta Agave brittoniana (Agavaceae) con actividad contra el parásito Trichomona vaginalis

Revista de biología tropical, 2007-10, Vol.56 (4)

2007

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Transformation of schiff bases derived from alpha-naphthaldehyde. Synthesis, spectral data and biological activity of new-3-aryl-2-(α-naphtyl)-4-thiazolidinones and N-aryl-N-[1-(α-naphthyl)but-3-enyl]amines

Journal of heterocyclic chemistry, 2004-11, Vol.41 (6), p.995-999

2004

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Experimental models in Chagas disease: a review of the methodologies applied for screening compounds against Trypanosoma cruzi

Development of novel benznidazole formulations: Physicochemical characterization and in vivo evaluation on parasitemia reduction in Chagas disease

5-Nitroindazole-based compounds: further studies for activity optimization as anti-Trypanosoma cruzi agents

Selective activity of 2,4-diaryl-1,2,3,4-tetrahydroquinolines on Trypanosoma cruzi epimastigotes and amastigotes expressing β-galactosidase

Development of resazurin microtiter assay for drug sensibility testing of Trypanosoma cruzi epimastigotes

Novel solid dispersions of benznidazole: Preparation, dissolution profile and biological evaluation as alternative antichagasic drug delivery system

Novel Imidazo[4,5-c][1,2,6]thiadiazine 2,2-dioxides as antiproliferative trypanosoma cruzi drugs: Computational screening from neural network, synthesis and in vivo biological properties

Bond-based bilinear indices for computational discovery of novel trypanosomicidal drug-like compounds through virtual screening

Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes

Drug repositioning for novel antitrichomonas from known antiprotozoan drugs using hierarchical screening

Selective activity of polyene macrolides produced by genetically modified Streptomyces on Trypanosoma cruzi

Ligand-based discovery of novel trypanosomicidal drug-like compounds: In silico identification and experimental support

Identification In Silico and In Vitro of Novel Trypanosomicidal Drug-Like Compounds

Activity profile of two 5-nitroindazole derivatives over the moderately drug-resistant Trypanosoma cruzi Y strain (DTU TcII): in vitro and in vivo studies

Saponinas esteroidales de la planta Agave brittoniana (Agavaceae) con actividad contra el parásito Trichomona vaginalis

Antiprotozoan lead discovery by aligning dry and wet screening: Prediction, synthesis, and biological assay of novel quinoxalinones

Biological Characterization of Trypanosoma cruzi Strains

Antiparasitic properties of homoallylamines and related compounds

Biological variability in clinical isolates of Trichomonas vaginalis

Relationship between biological behaviour and randomly amplified polymorphic DNA profiles of Trypanosoma cruzi strains

Steroidal saponins from the plant Agave brittoniana with activity against the parasite Trichomona vaginalis

Exploring the potential activity spectrum of two 5-nitroindazolinone prototypes on different Trypanosoma cruzi strains

Saponinas esteroidales de la planta Agave brittoniana (Agavaceae) con actividad contra el parásito Trichomona vaginalis

Saponinas esteroidales de la planta Agave brittoniana (Agavaceae) con actividad contra el parásito Trichomona vaginalis

Transformation of schiff bases derived from alpha-naphthaldehyde. Synthesis, spectral data and biological activity of new-3-aryl-2-(α-naphtyl)-4-thiazolidinones and N-aryl-N-[1-(α-naphthyl)but-3-enyl]amines

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