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Identification of allosteric inhibitors of the ecto-5'-nucleotidase (CD73) targeting the dimer interface

PLoS computational biology, 2018-01, Vol.14 (1), p.e1005943

2018

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Prognostic impact of cN-III mRNA expression on overall survival and drug sensitivity in pediatric leukemia

Leukemia & lymphoma, 2022-01, Vol.63 (2), p.457-462

2022

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Virtual screening and biological evaluation of inhibitors targeting the XPA-ERCC1 interaction

PloS one, 2012-12, Vol.7 (12), p.e51329

2012

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Enriched PUFA environment of Leishmania infantum promastigotes promotes the accumulation of lipid mediators and favors parasite infectivity towards J774 murine macrophages

Lipids, 2023-03, Vol.58 (2), p.81-92

2023

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PARP Inhibitors and Proteins Interacting with SLX4

Cancers, 2023-02, Vol.15 (3), p.997

Jordheim, Lars Petter

2023

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The ribonucleotide reductase large subunit (RRM1) as a predictive factor in patients with cancer

The lancet oncology, 2011-07, Vol.12 (7), p.693-702

2011

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Therapeutic perspectives for cN-II in cancer

Current medicinal chemistry, 2013-11, Vol.20 (34), p.4292

2013

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Expanding the clinical relevance of the 5′-nucleotidase cN-II/NT5C2

Purinergic signalling, 2018-12, Vol.14 (4), p.321-329

Jordheim, Lars Petter

2018

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Cytosolic 5'-nucleotidase II interacts with the leucin rich repeat of NLR family member Ipaf

PloS one, 2015-03, Vol.10 (3), p.e0121525-e0121525

2015

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Characterization of T‐DM1‐resistant breast cancer cells

Pharmacology research & perspectives, 2020-08, Vol.8 (4), p.e00617-n/a

2020

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Single nucleotide polymorphisms in ABCB1 and CBR1 can predict toxicity to R-CHOP type regimens in patients with diffuse non-Hodgkin lymphoma

Haematologica (Roma), 2015-05, Vol.100 (5), p.e204

2015

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Simultaneous analysis of eight nucleoside triphosphates in cell lines by liquid chromatography coupled with tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009-11, Vol.877 (30), p.3831-3840

2009

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Determination of the enzymatic activity of cytosolic 5′-nucleotidase cN-II in cancer cells: development of a simple analytical method and related cell line models

Analytical and bioanalytical chemistry, 2015-07, Vol.407 (19), p.5747-5758

2015

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Structural insights into the inhibition of cytosolic 5'-nucleotidase II (cN-II) by ribonucleoside 5'-monophosphate analogues

PLoS computational biology, 2011-12, Vol.7 (12), p.e1002295-e1002295

2011

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The Antitumor Activity of Combinations of Cytotoxic Chemotherapy and Immune Checkpoint Inhibitors Is Model-Dependent

Frontiers in immunology, 2018-10, Vol.9, p.2100-2100

2018

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Unexpected Growth-Promoting Effect of Oxaliplatin in Excision Repair Cross-Complementation Group 1 Transfected Human Colon Cancer Cells

Pharmacology, 2018-01, Vol.102 (3-4), p.161-168

2018

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A Proposed Methodology to Deal with the Impact of In Vitro Cellular Matrix on the Analytical Performances of a Targeted Metabolomic LC-HRMS Method

International journal of molecular sciences, 2023-02, Vol.24 (4), p.3770

2023

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Identification of Noncompetitive Inhibitors of Cytosolic 5′-Nucleotidase II Using a Fragment-Based Approach

Journal of medicinal chemistry, 2015-12, Vol.58 (24), p.9680-9696

2015

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Toward Personalization of Cytarabine Dosing in Acute Myeloid Leukemia

Journal of clinical oncology, 2022-03, Vol.40 (7), p.784-786

Jordheim, Lars Petter

2022

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OXPHOS inhibitors, metabolism and targeted therapies in cancer

Biochemical pharmacology, 2023-05, Vol.211, p.115531-115531, Article 115531

2023

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Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases

Nature reviews. Drug discovery, 2013-06, Vol.12 (6), p.447

2013

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Special feature of mixed phosphotriester derivatives of cytarabine

Bioorganic & medicinal chemistry, 2009-09, Vol.17 (17), p.6340-6347

2009

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Clinical use of biomarkers in the field of cytotoxic nucleoside analogues

Nucleosides, nucleotides & nucleic acids, 2023-10, p.1-9

Jordheim, Lars Petter

2023

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Beta-hydroxyphosphonate ribonucleoside analogues derived from 4-substituted-1,2,3-triazoles as IMP/GMP mimics: synthesis and biological evaluation

Beilstein journal of organic chemistry, 2016-07, Vol.12 (1), p.1476-1486

2016

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Cytosolic 5′-Nucleotidase II Silencing in Lung Tumor Cells Regulates Metabolism through Activation of the p53/AMPK Signaling Pathway

International journal of molecular sciences, 2021-07, Vol.22 (13), p.7004

2021

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Identification of allosteric inhibitors of the ecto-5'-nucleotidase (CD73) targeting the dimer interface

Prognostic impact of cN-III mRNA expression on overall survival and drug sensitivity in pediatric leukemia

Virtual screening and biological evaluation of inhibitors targeting the XPA-ERCC1 interaction

Enriched PUFA environment of Leishmania infantum promastigotes promotes the accumulation of lipid mediators and favors parasite infectivity towards J774 murine macrophages

PARP Inhibitors and Proteins Interacting with SLX4

The ribonucleotide reductase large subunit (RRM1) as a predictive factor in patients with cancer

Therapeutic perspectives for cN-II in cancer

Expanding the clinical relevance of the 5′-nucleotidase cN-II/NT5C2

Cytosolic 5'-nucleotidase II interacts with the leucin rich repeat of NLR family member Ipaf

Characterization of T‐DM1‐resistant breast cancer cells

Single nucleotide polymorphisms in ABCB1 and CBR1 can predict toxicity to R-CHOP type regimens in patients with diffuse non-Hodgkin lymphoma

Simultaneous analysis of eight nucleoside triphosphates in cell lines by liquid chromatography coupled with tandem mass spectrometry

Determination of the enzymatic activity of cytosolic 5′-nucleotidase cN-II in cancer cells: development of a simple analytical method and related cell line models

Structural insights into the inhibition of cytosolic 5'-nucleotidase II (cN-II) by ribonucleoside 5'-monophosphate analogues

The Antitumor Activity of Combinations of Cytotoxic Chemotherapy and Immune Checkpoint Inhibitors Is Model-Dependent

Unexpected Growth-Promoting Effect of Oxaliplatin in Excision Repair Cross-Complementation Group 1 Transfected Human Colon Cancer Cells

A Proposed Methodology to Deal with the Impact of In Vitro Cellular Matrix on the Analytical Performances of a Targeted Metabolomic LC-HRMS Method

Identification of Noncompetitive Inhibitors of Cytosolic 5′-Nucleotidase II Using a Fragment-Based Approach

Toward Personalization of Cytarabine Dosing in Acute Myeloid Leukemia

OXPHOS inhibitors, metabolism and targeted therapies in cancer

Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases

Special feature of mixed phosphotriester derivatives of cytarabine

Clinical use of biomarkers in the field of cytotoxic nucleoside analogues

Beta-hydroxyphosphonate ribonucleoside analogues derived from 4-substituted-1,2,3-triazoles as IMP/GMP mimics: synthesis and biological evaluation

Cytosolic 5′-Nucleotidase II Silencing in Lung Tumor Cells Regulates Metabolism through Activation of the p53/AMPK Signaling Pathway

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