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Current mechanistic understanding of thiamin diphosphate-dependent enzymatic reactions

Natural product reports, 2003-04, Vol.20 (2), p.184-201

Jordan, Frank

2003

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Catalysis in Enzymatic Decarboxylations: Comparison of Selected Cofactor-Dependent and Cofactor-Independent Examples

ACS catalysis, 2013-07, Vol.3 (7), p.1601-1617

2013

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Probing the E1o-E2o and E1a-E2o Interactions in Binary Subcomplexes of the Human 2-Oxoglutarate Dehydrogenase and 2-Oxoadipate Dehydrogenase Complexes by Chemical Cross-Linking Mass Spectrometry and Molecular Dynamics Simulation

International journal of molecular sciences, 2023-02, Vol.24 (5), p.4555

2023

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Conformational dynamics of 1-deoxy-D-xylulose 5-phosphate synthase on ligand binding revealed by H/D exchange MS

Proceedings of the National Academy of Sciences - PNAS, 2017-08, Vol.114 (35), p.9355-9360

2017

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Functional Genomics and Immunologic Tools: The Impact of Viral and Host Genetic Variations on the Outcome of Zika Virus Infection

Viruses, 2018-08, Vol.10 (8), p.422

2018

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Mice as an Animal Model for Japanese Encephalitis Virus Research: Mouse Susceptibility, Infection Route, and Viral Pathogenesis

Pathogens (Basel), 2023-05, Vol.12 (5), p.715

2023

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Development and characterization of type I interferon receptor knockout sheep: A model for viral immunology and reproductive signaling

Frontiers in genetics, 2022-09, Vol.13, p.986316-986316

2022

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Functional Versatility of the Human 2-Oxoadipate Dehydrogenase in the L-Lysine Degradation Pathway toward Its Non-Cognate Substrate 2-Oxopimelic Acid

International journal of molecular sciences, 2022-08, Vol.23 (15), p.8213

2022

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Development, Characterization, and Application of Two Reporter-Expressing Recombinant Zika Viruses

Viruses, 2020-05, Vol.12 (5), p.572

2020

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Recent Developments in Ruthenium-Catalyzed C–H Arylation: Array of Mechanistic Manifolds

ACS catalysis, 2017-09, Vol.7 (9), p.5721-5745

2017

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Toward an Understanding of the Structural and Mechanistic Aspects of Protein-Protein Interactions in 2-Oxoacid Dehydrogenase Complexes

Life (Basel, Switzerland), 2021-04, Vol.11 (5), p.407

2021

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Reaction mechanisms of thiamin diphosphate enzymes: defining states of ionization and tautomerization of the cofactor at individual steps

The FEBS journal, 2009-05, Vol.276 (9), p.2432-3446

2009

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Structure and Function of the Catalytic Domain of the Dihydrolipoyl Acetyltransferase Component in Escherichia coli Pyruvate Dehydrogenase Complex

The Journal of biological chemistry, 2014-05, Vol.289 (22), p.15215-15230

2014

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Piscivore Responses to Enhancement of the Channelized Kissimmee River, Florida, U.S.A

Restoration ecology, 2014-05, Vol.22 (3), p.418-425

2014

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Conformational Ensemble Modulates Cooperativity in the Rate-determining Catalytic Step in the E1 Component of the Escherichia coli Pyruvate Dehydrogenase Multienzyme Complex

The Journal of biological chemistry, 2009-11, Vol.284 (48), p.33122-33129

2009

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Double Duty for a Conserved Glutamate in Pyruvate Decarboxylase: Evidence of the Participation in Stereoelectronically Controlled Decarboxylation and in Protonation of the Nascent Carbanion/Enamine Intermediate

Biochemistry (Easton), 2010-09, Vol.49 (37), p.8197-8212

2010

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Individualized targeted treatment in a case of a rare TFG::ROS1 fusion positive inflammatory myofibroblastic tumor (IMT)

Cancer reports, 2024-01, Vol.7 (1), p.e1916-n/a

2024

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Ruthenium(II)-Catalyzed Direct C–H Arylation of Indoles with Arylsilanes in Water

Organic letters, 2018-01, Vol.20 (2), p.341-344

2018

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A Dynamic Loop at the Active Center of the Escherichia coli Pyruvate Dehydrogenase Complex E1 Component Modulates Substrate Utilization and Chemical Communication with the E2 Component

The Journal of biological chemistry, 2007-09, Vol.282 (38), p.28106-28116

2007

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A Thiamin-bound, Pre-decarboxylation Reaction Intermediate Analogue in the Pyruvate Dehydrogenase E1 Subunit Induces Large Scale Disorder-to-Order Transformations in the Enzyme and Reveals Novel Structural Features in the Covalently Bound Adduct

The Journal of biological chemistry, 2006-06, Vol.281 (22), p.15296-15303

2006

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Highly chemoselective ruthenium(ii)-catalyzed direct arylation of cyclic and N , N -dialkyl benzamides with aryl silanes

Chemical science (Cambridge), 2017-04, Vol.8 (4), p.3204-3210

2017

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1',4'-iminopyrimidine tautomer of thiamin diphosphate is poised for catalysis in asymmetric active centers on enzymes

Proceedings of the National Academy of Sciences - PNAS, 2007-01, Vol.104 (1), p.78-82

2007

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Engineering the 2-Oxoglutarate Dehydrogenase Complex to Understand Catalysis and Alter Substrate Recognition

Reactions (Basel, Switzerland), 2022-03, Vol.3 (1), p.139-159

2022

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Nuclear magnetic resonance approaches in the study of 2-oxo acid dehydrogenase multienzyme complexes--a literature review

Molecules, 2013-09, Vol.18 (10), p.11873-11903

2013

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Complete Genome Sequences of Three Historically Important, Spatiotemporally Distinct, and Genetically Divergent Strains of Zika Virus: MR-766, P6-740, and PRVABC-59

Genome announcements (Washington, DC), 2016-08, Vol.4 (4)

2016

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Current mechanistic understanding of thiamin diphosphate-dependent enzymatic reactions

Catalysis in Enzymatic Decarboxylations: Comparison of Selected Cofactor-Dependent and Cofactor-Independent Examples

Probing the E1o-E2o and E1a-E2o Interactions in Binary Subcomplexes of the Human 2-Oxoglutarate Dehydrogenase and 2-Oxoadipate Dehydrogenase Complexes by Chemical Cross-Linking Mass Spectrometry and Molecular Dynamics Simulation

Conformational dynamics of 1-deoxy-D-xylulose 5-phosphate synthase on ligand binding revealed by H/D exchange MS

Functional Genomics and Immunologic Tools: The Impact of Viral and Host Genetic Variations on the Outcome of Zika Virus Infection

Mice as an Animal Model for Japanese Encephalitis Virus Research: Mouse Susceptibility, Infection Route, and Viral Pathogenesis

Development and characterization of type I interferon receptor knockout sheep: A model for viral immunology and reproductive signaling

Functional Versatility of the Human 2-Oxoadipate Dehydrogenase in the L-Lysine Degradation Pathway toward Its Non-Cognate Substrate 2-Oxopimelic Acid

Development, Characterization, and Application of Two Reporter-Expressing Recombinant Zika Viruses

Recent Developments in Ruthenium-Catalyzed C–H Arylation: Array of Mechanistic Manifolds

Toward an Understanding of the Structural and Mechanistic Aspects of Protein-Protein Interactions in 2-Oxoacid Dehydrogenase Complexes

Reaction mechanisms of thiamin diphosphate enzymes: defining states of ionization and tautomerization of the cofactor at individual steps

Structure and Function of the Catalytic Domain of the Dihydrolipoyl Acetyltransferase Component in Escherichia coli Pyruvate Dehydrogenase Complex

Piscivore Responses to Enhancement of the Channelized Kissimmee River, Florida, U.S.A

Conformational Ensemble Modulates Cooperativity in the Rate-determining Catalytic Step in the E1 Component of the Escherichia coli Pyruvate Dehydrogenase Multienzyme Complex

Double Duty for a Conserved Glutamate in Pyruvate Decarboxylase: Evidence of the Participation in Stereoelectronically Controlled Decarboxylation and in Protonation of the Nascent Carbanion/Enamine Intermediate

Individualized targeted treatment in a case of a rare TFG::ROS1 fusion positive inflammatory myofibroblastic tumor (IMT)

Ruthenium(II)-Catalyzed Direct C–H Arylation of Indoles with Arylsilanes in Water

A Dynamic Loop at the Active Center of the Escherichia coli Pyruvate Dehydrogenase Complex E1 Component Modulates Substrate Utilization and Chemical Communication with the E2 Component

A Thiamin-bound, Pre-decarboxylation Reaction Intermediate Analogue in the Pyruvate Dehydrogenase E1 Subunit Induces Large Scale Disorder-to-Order Transformations in the Enzyme and Reveals Novel Structural Features in the Covalently Bound Adduct

Highly chemoselective ruthenium(ii)-catalyzed direct arylation of cyclic and N , N -dialkyl benzamides with aryl silanes

1',4'-iminopyrimidine tautomer of thiamin diphosphate is poised for catalysis in asymmetric active centers on enzymes

Engineering the 2-Oxoglutarate Dehydrogenase Complex to Understand Catalysis and Alter Substrate Recognition

Nuclear magnetic resonance approaches in the study of 2-oxo acid dehydrogenase multienzyme complexes--a literature review

Complete Genome Sequences of Three Historically Important, Spatiotemporally Distinct, and Genetically Divergent Strains of Zika Virus: MR-766, P6-740, and PRVABC-59

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