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Population pharmacokinetic analysis of etrolizumab in patients with moderately‐to‐severely active ulcerative colitis

CPT: pharmacometrics and systems pharmacology, 2022-09, Vol.11 (9), p.1244-1255

2022

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Interleukin-1 system in CNS stress: seizures, fever, and neurotrauma

Annals of the New York Academy of Sciences, 2007-10, Vol.1113 (1), p.173-177

2007

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Pharmacometrics-Based Considerations for the Design of a Pharmacogenomic Clinical Trial Assessing Irinotecan Safety

Pharmaceutical research, 2021-04, Vol.38 (4), p.593-605

2021

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Pharmacokinetics and dose requirements of factor VIII over the age range 3-74 years

European journal of clinical pharmacology, 2009-06, Vol.65 (10), p.989-998

2009

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Model‐based evaluation of low‐dose factor VIII prophylaxis in haemophilia A

Haemophilia : the official journal of the World Federation of Hemophilia, 2019-05, Vol.25 (3), p.408-415

2019

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Population pharmacokinetic and dose-response models of nepadutant, a selective antagonist of the NK2 receptors, in infants with colic

British journal of clinical pharmacology, 2024-09

2024

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Therapeutic drug monitoring of vancomycin and meropenem: Illustration of the impact of inaccurate information in dose administration time

International journal of antimicrobial agents, 2024-01, Vol.63 (1), p.107032-107032, Article 107032

2024

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Handling interoccasion variability in model‐based dose individualization using therapeutic drug monitoring data

British journal of clinical pharmacology, 2019-06, Vol.85 (6), p.1326-1336

2019

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Population pharmacokinetics of cefotaxime in intensive care patients

European journal of clinical pharmacology, 2022-02, Vol.78 (2), p.251-258

2022

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Combining mathematical modeling, in vitro data and clinical target expression to support bispecific antibody binding affinity selection: a case example with FAP-4-1BBL

Frontiers in pharmacology, 2024-10, Vol.15, p.1472662

2024

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Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients

Haematologica (Roma), 2020-05, Vol.105 (5), p.1443-1453

2020

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Association between Sports Participation, Factor VIII Levels and Bleeding in Hemophilia A

Thrombosis and haemostasis, 2023-03, Vol.123 (3), p.317-325

2023

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Population pharmacokinetics of edoxaban and its main metabolite in a dedicated renal impairment study

Journal of clinical pharmacology, 2015-11, Vol.55 (11), p.1268-1279

2015

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Exploring Factors Causing Low Brain Penetration of the Opioid Peptide DAMGO through Experimental Methods and Modeling

Molecular pharmaceutics, 2016-04, Vol.13 (4), p.1258-1266

2016

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Characterization of anti-drug antibody dynamics using a bivariate mixed hidden-markov model by nonlinear-mixed effects approach

Journal of pharmacokinetics and pharmacodynamics, 2024-02, Vol.51 (1), p.65-75

2024

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Model-Based Characterization of the Bidirectional Interaction Between Pharmacokinetics and Tumor Growth Dynamics in Patients with Metastatic Merkel Cell Carcinoma Treated with Avelumab

Clinical cancer research, 2022-04, Vol.28 (7), p.1363-1371

2022

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Detecting placebo and drug effects on Parkinson's disease symptoms by longitudinal item‐score models

CPT: pharmacometrics and systems pharmacology, 2021-04, Vol.10 (4), p.309-317

2021

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A diagnostic tool for population models using non-compartmental analysis: The ncappc package for R

Computer methods and programs in biomedicine, 2016-04, Vol.127, p.83-93

2016

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Population Pharmacokinetics of Ethambutol in South African Tuberculosis Patients

Antimicrobial Agents and Chemotherapy, 2011-09, Vol.55 (9), p.4230-4237

2011

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Population Pharmacokinetics of Edoxaban in Patients with Non-Valvular Atrial Fibrillation in the ENGAGE AF-TIMI 48 Study, a Phase III Clinical Trial

Clinical pharmacokinetics, 2016-09, Vol.55 (9), p.1079-1090

2016

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Role of Modelling and Simulation: A European Regulatory Perspective

Clinical pharmacokinetics, 2012-01, Vol.51 (2), p.69-76

2012

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Population pharmacokinetics of edoxaban in patients with symptomatic deep‐vein thrombosis and/or pulmonary embolism—the Hokusai‐VTE phase 3 study

British journal of clinical pharmacology, 2015-12, Vol.80 (6), p.1374-1387

2015

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Interleukin-1 System in CNS Stress

Annals of the New York Academy of Sciences, 2007-10, Vol.1113 (1), p.173-177

2007

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Bayesian Forecasting Utilizing Bleeding Information to Support Dose Individualization of Factor VIII

CPT: pharmacometrics and systems pharmacology, 2019-12, Vol.8 (12), p.894-903

2019

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Generating evidence for precision medicine: considerations made by the Ubiquitous Pharmacogenomics Consortium when designing and operationalizing the PREPARE study

Population pharmacokinetic analysis of etrolizumab in patients with moderately‐to‐severely active ulcerative colitis

Interleukin-1 system in CNS stress: seizures, fever, and neurotrauma

Pharmacometrics-Based Considerations for the Design of a Pharmacogenomic Clinical Trial Assessing Irinotecan Safety

Pharmacokinetics and dose requirements of factor VIII over the age range 3-74 years

Model‐based evaluation of low‐dose factor VIII prophylaxis in haemophilia A

Population pharmacokinetic and dose-response models of nepadutant, a selective antagonist of the NK2 receptors, in infants with colic

Therapeutic drug monitoring of vancomycin and meropenem: Illustration of the impact of inaccurate information in dose administration time

Handling interoccasion variability in model‐based dose individualization using therapeutic drug monitoring data

Population pharmacokinetics of cefotaxime in intensive care patients

Combining mathematical modeling, in vitro data and clinical target expression to support bispecific antibody binding affinity selection: a case example with FAP-4-1BBL

Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients

Association between Sports Participation, Factor VIII Levels and Bleeding in Hemophilia A

Population pharmacokinetics of edoxaban and its main metabolite in a dedicated renal impairment study

Exploring Factors Causing Low Brain Penetration of the Opioid Peptide DAMGO through Experimental Methods and Modeling

Characterization of anti-drug antibody dynamics using a bivariate mixed hidden-markov model by nonlinear-mixed effects approach

Model-Based Characterization of the Bidirectional Interaction Between Pharmacokinetics and Tumor Growth Dynamics in Patients with Metastatic Merkel Cell Carcinoma Treated with Avelumab

Detecting placebo and drug effects on Parkinson's disease symptoms by longitudinal item‐score models

A diagnostic tool for population models using non-compartmental analysis: The ncappc package for R

Population Pharmacokinetics of Ethambutol in South African Tuberculosis Patients

Population Pharmacokinetics of Edoxaban in Patients with Non-Valvular Atrial Fibrillation in the ENGAGE AF-TIMI 48 Study, a Phase III Clinical Trial

Role of Modelling and Simulation: A European Regulatory Perspective

Population pharmacokinetics of edoxaban in patients with symptomatic deep‐vein thrombosis and/or pulmonary embolism—the Hokusai‐VTE phase 3 study

Interleukin-1 System in CNS Stress

Bayesian Forecasting Utilizing Bleeding Information to Support Dose Individualization of Factor VIII

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