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PsN-Toolkit—A collection of computer intensive statistical methods for non-linear mixed effect modeling using NONMEM

Computer methods and programs in biomedicine, 2005-09, Vol.79 (3), p.241-257

2005

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Full random effects models (FREM): A practical usage guide

CPT: pharmacometrics and systems pharmacology, 2024-08, Vol.13 (8), p.1297-1308

2024

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Using forest plots to interpret covariate effects in pharmacometric models

CPT: pharmacometrics and systems pharmacology, 2024-05, Vol.13 (5), p.743-758

2024

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Efficient and relevant stepwise covariate model building for pharmacometrics

CPT: pharmacometrics and systems pharmacology, 2022-09, Vol.11 (9), p.1210-1222

2022

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Population pharmacokinetic analysis of tepotinib, an oral MET kinase inhibitor, including data from the VISION study

Cancer chemotherapy and pharmacology, 2022-05, Vol.89 (5), p.655-669

2022

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A quantitative approach to the choice of number of samples for percentile estimation in bootstrap and visual predictive check analyses

CPT: pharmacometrics and systems pharmacology, 2022-06, Vol.11 (6), p.673-686

2022

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Conditional distribution modeling as an alternative method for covariates simulation: Comparison with joint multivariate normal and bootstrap techniques

CPT: pharmacometrics and systems pharmacology, 2021-04, Vol.10 (4), p.330-339

2021

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Power, selection bias and predictive performance of the population pharmacokinetic covariate model

Journal of pharmacokinetics and pharmacodynamics, 2004-04, Vol.31 (2), p.109-134

2004

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An introduction to the full random effects model

CPT: pharmacometrics and systems pharmacology, 2022-02, Vol.11 (2), p.149-160

2022

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A Physiologically-Based Pharmacokinetic Framework for Prediction of Drug Exposure in Malnourished Children

Pharmaceutics, 2021-02, Vol.13 (2), p.204

2021

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PharmTeX: a LaTeX-Based Open-Source Platform for Automated Reporting Workflow

The AAPS journal, 2018-05, Vol.20 (3), p.52-52, Article 52

2018

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A Fast Method for Testing Covariates in Population PK/PD Models

The AAPS journal, 2011-09, Vol.13 (3), p.464, Article 464

2011

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Properties of the full random‐effect modeling approach with missing covariate data

Statistics in medicine, 2024-02, Vol.43 (5), p.935-952

2024

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The lasso--a novel method for predictive covariate model building in nonlinear mixed effects models

Journal of pharmacokinetics and pharmacodynamics, 2007-08, Vol.34 (4), p.485-517

2007

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Population pharmacokinetic and dose-response models of nepadutant, a selective antagonist of the NK2 receptors, in infants with colic

British journal of clinical pharmacology, 2024-09

2024

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Population pharmacokinetic and dose-response models of nepadutant, a selective antagonist of the NK 2 receptors, in infants with colic

British journal of clinical pharmacology, 2024-09

2024

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Automated covariate model building within NONMEM

Pharmaceutical research, 1998-09, Vol.15 (9), p.1463-1468

1998

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A PK/PD Analysis of Circulating Biomarkers and Their Relationship to Tumor Response in Atezolizumab‐Treated non‐small Cell Lung Cancer Patients

Clinical pharmacology and therapeutics, 2019-02, Vol.105 (2), p.486-495

2019

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Perl-speaks-NONMEM (PsN)—a Perl module for NONMEM related programming

Computer methods and programs in biomedicine, 2004-08, Vol.75 (2), p.85-94

2004

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An integrated model for the analysis of pharmacokinetic data from microdialysis experiments

Pharmaceutical research, 2004-09, Vol.21 (9), p.1698-1707

2004

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Population pharmacokinetics of tanezumab in phase 3 clinical trials for osteoarthritis pain

British journal of clinical pharmacology, 2016-04, Vol.81 (4), p.688-699

2016

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Population pharmacokinetic/pharmacodynamic (PK/PD) modelling of the hypothalamic–pituitary–gonadal axis following treatment with GnRH analogues

British journal of clinical pharmacology, 2007-06, Vol.63 (6), p.648-664

2007

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Population Pharmacokinetics of a Novel Once-Every 3 Months Intramuscular Formulation of Paliperidone Palmitate in Patients with Schizophrenia

Clinical pharmacokinetics, 2017-04, Vol.56 (4), p.421-433

2017

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A Bayesian decision support tool for efficient dose individualization of warfarin in adults and children

BMC medical informatics and decision making, 2015-02, Vol.15 (1), p.7-7, Article 7

2015

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Randomized exposure‐controlled trials; impact of randomization and analysis strategies

British journal of clinical pharmacology, 2007-09, Vol.64 (3), p.266-277

2007

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PsN-Toolkit—A collection of computer intensive statistical methods for non-linear mixed effect modeling using NONMEM

Full random effects models (FREM): A practical usage guide

Using forest plots to interpret covariate effects in pharmacometric models

Efficient and relevant stepwise covariate model building for pharmacometrics

Population pharmacokinetic analysis of tepotinib, an oral MET kinase inhibitor, including data from the VISION study

A quantitative approach to the choice of number of samples for percentile estimation in bootstrap and visual predictive check analyses

Conditional distribution modeling as an alternative method for covariates simulation: Comparison with joint multivariate normal and bootstrap techniques

Power, selection bias and predictive performance of the population pharmacokinetic covariate model

An introduction to the full random effects model

A Physiologically-Based Pharmacokinetic Framework for Prediction of Drug Exposure in Malnourished Children

PharmTeX: a LaTeX-Based Open-Source Platform for Automated Reporting Workflow

A Fast Method for Testing Covariates in Population PK/PD Models

Properties of the full random‐effect modeling approach with missing covariate data

The lasso--a novel method for predictive covariate model building in nonlinear mixed effects models

Population pharmacokinetic and dose-response models of nepadutant, a selective antagonist of the NK2 receptors, in infants with colic

Population pharmacokinetic and dose-response models of nepadutant, a selective antagonist of the NK 2 receptors, in infants with colic

Automated covariate model building within NONMEM

A PK/PD Analysis of Circulating Biomarkers and Their Relationship to Tumor Response in Atezolizumab‐Treated non‐small Cell Lung Cancer Patients

Perl-speaks-NONMEM (PsN)—a Perl module for NONMEM related programming

An integrated model for the analysis of pharmacokinetic data from microdialysis experiments

Population pharmacokinetics of tanezumab in phase 3 clinical trials for osteoarthritis pain

Population pharmacokinetic/pharmacodynamic (PK/PD) modelling of the hypothalamic–pituitary–gonadal axis following treatment with GnRH analogues

Population Pharmacokinetics of a Novel Once-Every 3 Months Intramuscular Formulation of Paliperidone Palmitate in Patients with Schizophrenia

A Bayesian decision support tool for efficient dose individualization of warfarin in adults and children

Randomized exposure‐controlled trials; impact of randomization and analysis strategies

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