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Xpose : an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM

Computer methods and programs in biomedicine, 1999, Vol.58 (1), p.51-64

1999

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Automated covariate model building within NONMEM

Pharmaceutical research, 1998-09, Vol.15 (9), p.1463-1468

1998

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Perl-speaks-NONMEM (PsN)—a Perl module for NONMEM related programming

Computer methods and programs in biomedicine, 2004-08, Vol.75 (2), p.85-94

2004

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Population pharmacokinetic analysis resulting in a tool for dose individualization of busulphan in bone marrow transplantation recipients

Bone marrow transplantation (Basingstoke), 2001-10, Vol.28 (7), p.657-664

2001

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A PK–PD Model for Predicting the Impact of Age, CYP2C9, and VKORC1 Genotype on Individualization of Warfarin Therapy

Clinical pharmacology and therapeutics, 2007-04, Vol.81 (4), p.529-538

2007

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A Pharmacometric Model Describing the Relationship Between Warfarin Dose and INR Response With Respect to Variations in CYP2C9, VKORC1, and Age

Clinical pharmacology and therapeutics, 2010-06, Vol.87 (6), p.727-734

2010

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Power, selection bias and predictive performance of the population pharmacokinetic covariate model

Journal of pharmacokinetics and pharmacodynamics, 2004-04, Vol.31 (2), p.109-134

2004

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A Pharmacokinetic-pharmacodynamic Model for the Quantitative Prediction of Dofetilide Clinical QT Prolongation from Human Ether-a-go-go-related Gene Current Inhibition Data

Clinical pharmacology and therapeutics, 2005-06, Vol.77 (6), p.572-582

2005

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Comparisons of Analysis Methods for Proof‐of‐Concept Trials

CPT: pharmacometrics and systems pharmacology, 2013-01, Vol.2 (1), p.1-8

2013

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Assessment of actual significance levels for covariate effects in NONMEM

Journal of pharmacokinetics and pharmacodynamics, 2001-06, Vol.28 (3), p.231-252

2001

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Morphine blood-brain barrier transport is influenced by probenecid co-administration

Pharmaceutical research, 2003-04, Vol.20 (4), p.618-623

2003

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An integrated model for the analysis of pharmacokinetic data from microdialysis experiments

Pharmaceutical research, 2004-09, Vol.21 (9), p.1698-1707

2004

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Population exposure-response modeling of oral Nepadutant administration in Colicky infants

Clinical therapeutics, 2015-08, Vol.37 (8), p.e115-e115

2015

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Narratives Crossing Borders: The Dynamics of Cultural Interaction

2021

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More efficient clinical trials through use of scientific model-based statistical tests

Clinical pharmacology and therapeutics, 2002-12, Vol.72 (6), p.603-614

2002

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Probing Sponge-Derived Terpenoids for Human 15-Lipoxygenase Inhibitors

Journal of organic chemistry, 2001-10, Vol.66 (21), p.6847-6851

2001

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Stochastic differential equations in NONMEM: implementation, application, and comparison with ordinary differential equations

Pharmaceutical research, 2005-08, Vol.22 (8), p.1247-1258

2005

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Influence of probenecid on the delivery of morphine-6-glucuronide to the brain

European journal of pharmaceutical sciences, 2005, Vol.24 (1), p.49-57

2005

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Bridging the pharmacokinetics and pharmacodynamics of UK-279,276 across healthy volunteers and stroke patients using a mechanistically based model for target-mediated disposition

Pharmaceutical research, 2005-08, Vol.22 (8), p.1236-1246

2005

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Population pharmacokinetics of levosimendan in patients with congestive heart failure

British journal of clinical pharmacology, 2003-06, Vol.55 (6), p.544-551

2003

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Non-linear mixed-effects pharmacokinetic/pharmacodynamic modelling in NLME using differential equations

Computer methods and programs in biomedicine, 2004-10, Vol.76 (1), p.31-40

2004

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Population pharmacokinetic modeling of a subcutaneous depot for GnRH antagonist degarelix

Pharmaceutical research, 2004-04, Vol.21 (4), p.574-584

2004

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Assumption testing in population pharmacokinetic models : Illustrated with an analysis of moxonidine data from congestive heart failure patients

Journal of pharmacokinetics and biopharmaceutics, 1998-04, Vol.26 (2), p.207-246

1998

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Population pharmacokinetics of clomethiazole and its effect on the natural course of sedation in acute stroke patients

British journal of clinical pharmacology, 2003-08, Vol.56 (2), p.173-183

2003

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A longitudinal model for non-monotonic clinical assessment scale data

Journal of pharmacokinetics and pharmacodynamics, 2005-12, Vol.32 (5-6), p.795-815

2005

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Xpose : an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM

Automated covariate model building within NONMEM

Perl-speaks-NONMEM (PsN)—a Perl module for NONMEM related programming

Population pharmacokinetic analysis resulting in a tool for dose individualization of busulphan in bone marrow transplantation recipients

A PK–PD Model for Predicting the Impact of Age, CYP2C9, and VKORC1 Genotype on Individualization of Warfarin Therapy

A Pharmacometric Model Describing the Relationship Between Warfarin Dose and INR Response With Respect to Variations in CYP2C9, VKORC1, and Age

Power, selection bias and predictive performance of the population pharmacokinetic covariate model

A Pharmacokinetic-pharmacodynamic Model for the Quantitative Prediction of Dofetilide Clinical QT Prolongation from Human Ether-a-go-go-related Gene Current Inhibition Data

Comparisons of Analysis Methods for Proof‐of‐Concept Trials

Assessment of actual significance levels for covariate effects in NONMEM

Morphine blood-brain barrier transport is influenced by probenecid co-administration

An integrated model for the analysis of pharmacokinetic data from microdialysis experiments

Population exposure-response modeling of oral Nepadutant administration in Colicky infants

Narratives Crossing Borders: The Dynamics of Cultural Interaction

More efficient clinical trials through use of scientific model-based statistical tests

Probing Sponge-Derived Terpenoids for Human 15-Lipoxygenase Inhibitors

Stochastic differential equations in NONMEM: implementation, application, and comparison with ordinary differential equations

Influence of probenecid on the delivery of morphine-6-glucuronide to the brain

Bridging the pharmacokinetics and pharmacodynamics of UK-279,276 across healthy volunteers and stroke patients using a mechanistically based model for target-mediated disposition

Population pharmacokinetics of levosimendan in patients with congestive heart failure

Non-linear mixed-effects pharmacokinetic/pharmacodynamic modelling in NLME using differential equations

Population pharmacokinetic modeling of a subcutaneous depot for GnRH antagonist degarelix

Assumption testing in population pharmacokinetic models : Illustrated with an analysis of moxonidine data from congestive heart failure patients

Population pharmacokinetics of clomethiazole and its effect on the natural course of sedation in acute stroke patients

A longitudinal model for non-monotonic clinical assessment scale data

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