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A PK–PD Model for Predicting the Impact of Age, CYP2C9, and VKORC1 Genotype on Individualization of Warfarin Therapy

Clinical pharmacology and therapeutics, 2007-04, Vol.81 (4), p.529-538

2007

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A Comprehensive Hepatitis C Viral Kinetic Model Explaining Cure

Clinical pharmacology and therapeutics, 2010-06, Vol.87 (6), p.706-713

2010

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Xpose : an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM

Computer methods and programs in biomedicine, 1999, Vol.58 (1), p.51-64

1999

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A Pharmacometric Model Describing the Relationship Between Warfarin Dose and INR Response With Respect to Variations in CYP2C9, VKORC1, and Age

Clinical pharmacology and therapeutics, 2010-06, Vol.87 (6), p.727-734

2010

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Automated covariate model building within NONMEM

Pharmaceutical research, 1998-09, Vol.15 (9), p.1463-1468

1998

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Diurnal variation in serum levels of cartilage oligomeric matrix protein in patients with knee osteoarthritis or rheumatoid arthritis

Annals of the rheumatic diseases, 2006-11, Vol.65 (11), p.1490-1494

2006

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Comparisons of Analysis Methods for Proof‐of‐Concept Trials

CPT: pharmacometrics and systems pharmacology, 2013-01, Vol.2 (1), p.1-8

2013

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Assessment of actual significance levels for covariate effects in NONMEM

Journal of pharmacokinetics and pharmacodynamics, 2001-06, Vol.28 (3), p.231-252

2001

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Population pharmacokinetic analysis resulting in a tool for dose individualization of busulphan in bone marrow transplantation recipients

Bone marrow transplantation (Basingstoke), 2001-10, Vol.28 (7), p.657-664

2001

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Probing Sponge-Derived Terpenoids for Human 15-Lipoxygenase Inhibitors

Journal of organic chemistry, 2001-10, Vol.66 (21), p.6847-6851

2001

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Assumption testing in population pharmacokinetic models : Illustrated with an analysis of moxonidine data from congestive heart failure patients

Journal of pharmacokinetics and biopharmaceutics, 1998-04, Vol.26 (2), p.207-246

1998

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Artemisinin population pharmacokinetics in children and adults with uncomplicated falciparum malaria

British journal of clinical pharmacology, 1998-04, Vol.45 (4), p.347-354

1998

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Likelihood-based diagnostics for influential individuals in non-linear mixed effects model selection

Pharmaceutical research, 1999-08, Vol.16 (8), p.1260-1265

1999

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Perl-speaks-NONMEM (PsN)—a Perl module for NONMEM related programming

Computer methods and programs in biomedicine, 2004-08, Vol.75 (2), p.85-94

2004

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Discrimination between rival dosing histories

Pharmaceutical research, 1997-08, Vol.14 (8), p.984-991

1997

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Assessment of type I error rates for the statistical sub-model in NONMEM

Journal of pharmacokinetics and pharmacodynamics, 2002-06, Vol.29 (3), p.251-269

2002

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A PKPD analysis of circulating biomarkers and their relationship to the tumor size time-course in atezolizumab treated non-small cell lung cancer patients

Journal of pharmacokinetics and pharmacodynamics, 2017, Vol.44, p.S76

2017

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Power, selection bias and predictive performance of the population pharmacokinetic covariate model

Journal of pharmacokinetics and pharmacodynamics, 2004-04, Vol.31 (2), p.109-134

2004

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A Pharmacokinetic-pharmacodynamic Model for the Quantitative Prediction of Dofetilide Clinical QT Prolongation from Human Ether-a-go-go-related Gene Current Inhibition Data

Clinical pharmacology and therapeutics, 2005-06, Vol.77 (6), p.572-582

2005

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Morphine blood-brain barrier transport is influenced by probenecid co-administration

Pharmaceutical research, 2003-04, Vol.20 (4), p.618-623

2003

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An integrated model for the analysis of pharmacokinetic data from microdialysis experiments

Pharmaceutical research, 2004-09, Vol.21 (9), p.1698-1707

2004

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A Pharmacometric Model Describing the Relationship Between Warfarin Dose and INR Response With Respect to Variations i n CYP2C9, VKORC1, and Age

Clinical pharmacology and therapeutics, 2010, Vol.87 (6), p.727-734

2010

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Population exposure-response modeling of oral Nepadutant administration in Colicky infants

Clinical therapeutics, 2015-08, Vol.37 (8), p.e115-e115

2015

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Persistence and Variability of Earth’s Interhemispheric Albedo Symmetry in 19 Years of CERES EBAF Observations

Journal of climate, 2022-01, Vol.35 (1), p.249-268

2022

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More efficient clinical trials through use of scientific model-based statistical tests

Clinical pharmacology and therapeutics, 2002-12, Vol.72 (6), p.603-614

2002

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A PK–PD Model for Predicting the Impact of Age, CYP2C9, and VKORC1 Genotype on Individualization of Warfarin Therapy

A Comprehensive Hepatitis C Viral Kinetic Model Explaining Cure

Xpose : an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM

A Pharmacometric Model Describing the Relationship Between Warfarin Dose and INR Response With Respect to Variations in CYP2C9, VKORC1, and Age

Automated covariate model building within NONMEM

Diurnal variation in serum levels of cartilage oligomeric matrix protein in patients with knee osteoarthritis or rheumatoid arthritis

Comparisons of Analysis Methods for Proof‐of‐Concept Trials

Assessment of actual significance levels for covariate effects in NONMEM

Population pharmacokinetic analysis resulting in a tool for dose individualization of busulphan in bone marrow transplantation recipients

Probing Sponge-Derived Terpenoids for Human 15-Lipoxygenase Inhibitors

Assumption testing in population pharmacokinetic models : Illustrated with an analysis of moxonidine data from congestive heart failure patients

Artemisinin population pharmacokinetics in children and adults with uncomplicated falciparum malaria

Likelihood-based diagnostics for influential individuals in non-linear mixed effects model selection

Perl-speaks-NONMEM (PsN)—a Perl module for NONMEM related programming

Discrimination between rival dosing histories

Assessment of type I error rates for the statistical sub-model in NONMEM

A PKPD analysis of circulating biomarkers and their relationship to the tumor size time-course in atezolizumab treated non-small cell lung cancer patients

Power, selection bias and predictive performance of the population pharmacokinetic covariate model

A Pharmacokinetic-pharmacodynamic Model for the Quantitative Prediction of Dofetilide Clinical QT Prolongation from Human Ether-a-go-go-related Gene Current Inhibition Data

Morphine blood-brain barrier transport is influenced by probenecid co-administration

An integrated model for the analysis of pharmacokinetic data from microdialysis experiments

A Pharmacometric Model Describing the Relationship Between Warfarin Dose and INR Response With Respect to Variations i n CYP2C9, VKORC1, and Age

Population exposure-response modeling of oral Nepadutant administration in Colicky infants

Persistence and Variability of Earth’s Interhemispheric Albedo Symmetry in 19 Years of CERES EBAF Observations

More efficient clinical trials through use of scientific model-based statistical tests

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