UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 185

Sortiert nach

Interspecies evaluation of a physiologically based pharmacokinetic model to predict the biodistribution dynamics of dendritic nanoparticles

PloS one, 2023-05, Vol.18 (5), p.e0285798-e0285798

2023

Volltextzugriff (PDF)

PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration–time profiles in human by using the physiologically‐based pharmacokinetic modeling approach

Journal of pharmaceutical sciences, 2011-10, Vol.100 (10), p.4127-4157

2011

Volltextzugriff (PDF)

Quantitative Evaluation of Dendritic Nanoparticles in Mice: Biodistribution Dynamics and Downstream Tumor Efficacy Outcomes

Molecular pharmaceutics, 2022-01, Vol.19 (1), p.172-187

2022

Volltextzugriff (PDF)

A pharmacokinetic–pharmacodynamic model for the MET tyrosine kinase inhibitor, savolitinib, to explore target inhibition requirements for anti‐tumour activity

British journal of pharmacology, 2021-02, Vol.178 (3), p.600-613

2021

Volltextzugriff (PDF)

PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 4: Prediction of plasma concentration–time profiles in human from in vivo preclinical data by using the Wajima approach

Journal of pharmaceutical sciences, 2011-10, Vol.100 (10), p.4111-4126

2011

Volltextzugriff (PDF)

Improving the Accuracy of Predicted Human Pharmacokinetics: Lessons Learned from the AstraZeneca Drug Pipeline Over Two Decades

Trends in pharmacological sciences (Regular ed.), 2020-06, Vol.41 (6), p.390-408

2020

Volltextzugriff (PDF)

Pharmacokinetic/Pharmacodynamic Analysis of Savolitinib plus Osimertinib in an EGFR Mutation-Positive, MET-Amplified Non-Small Cell Lung Cancer Model

Molecular cancer therapeutics, 2023-05, Vol.22 (5), p.679-690

2023

Volltextzugriff (PDF)

A PKPD Case Study: Achieving Clinically Relevant Exposures of AZD5991 in Oncology Mouse Models

The AAPS journal, 2023-06, Vol.25 (4), p.66-66, Article 66

2023

Volltextzugriff (PDF)

Post-pastoral? Rethinking religion and the reconstruction of rural space

Journal of rural studies, 2016-06, Vol.45, p.15-23

2016

Volltextzugriff (PDF)

Reduction in systolic blood pressure following dietary fibre intervention is dependent on baseline gut microbiota composition

Proceedings of the Nutrition Society, 2024-04, Vol.83 (OCE1), Article E14

2024

Volltextzugriff (PDF)

The Pharmacokinetic-Pharmacodynamic (PKPD) Relationships of AZD3229, a Novel and Selective Inhibitor of KIT, in a Range of Mouse Xenograft Models of GIST

Clinical cancer research, 2020-07, Vol.26 (14), p.3751-3759

2020

Volltextzugriff (PDF)

The MET Inhibitor AZD6094 (Savolitinib, HMPL-504) Induces Regression in Papillary Renal Cell Carcinoma Patient-Derived Xenograft Models

Clinical cancer research, 2015-06, Vol.21 (12), p.2811-2819

2015

Volltextzugriff (PDF)

Applications of Quantitative Systems Pharmacology in Model‐Informed Drug Discovery: Perspective on Impact and Opportunities

CPT: pharmacometrics and systems pharmacology, 2019-11, Vol.8 (11), p.777-791

2019

Volltextzugriff (PDF)

Quantitative evaluation of trastuzumab deruxtecan pharmacokinetics and pharmacodynamics in mouse models of varying degrees of HER2 expression

CPT: pharmacometrics and systems pharmacology, 2024-06, Vol.13 (6), p.994-1005

2024

Volltextzugriff (PDF)

Developing PreDICT – a fully integrated data platform for preclinical in vivo data: learning from experience

Drug discovery today, 2017-10, Vol.22 (10), p.1539-1546

2017

Volltextzugriff (PDF)

Model-based drug discovery: implementation and impact

Drug discovery today, 2013-08, Vol.18 (15-16), p.764-775

2013

Volltextzugriff (PDF)

AZD3514: a small molecule that modulates androgen receptor signaling and function in vitro and in vivo

Molecular cancer therapeutics, 2013-09, Vol.12 (9), p.1715-1727

2013

Volltextzugriff (PDF)

Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer

Bioorganic & medicinal chemistry letters, 2013-04, Vol.23 (7), p.1945-1948

2013

Volltextzugriff (PDF)

Fuels and Fuel Technology: A Summarized Manual in Two Volumes

Abr. 2nd Ed., 2016

Volltextzugriff (PDF)

Novel one pot synthesis of silver nanoparticle-polymer composites by supercritical CO2 polymerisation in the presence of a RAFT agent

Chemical communications (Cambridge, England), 2007-01 (38), p.3933-3935

2007

Volltextzugriff (PDF)

The discovery of indole-derived long acting β2-adrenoceptor agonists for the treatment of asthma and COPD

Bioorganic & medicinal chemistry letters, 2007-11, Vol.17 (22), p.6188-6191

2007

Volltextzugriff (PDF)

Further Considerations Towards an Effective and Efficient Oncology Drug Discovery DMPK Strategy

Current drug metabolism, 2020-01, Vol.21 (2), p.145

2020

Volltextzugriff (PDF)

Abstract 1328: Exploring the pharmacokinetic-pharmacodynamic relationships of AZD3229, a novel and selective inhibitor of cKIT, in a range of mouse xenograft models of gastrointestinal stromal tumors

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.1328-1328

2019

Volltextzugriff (PDF)

Abstract 4263: A semi-mechanistic pharmacokinetic-pharmacodynamic (PK-PD) model of savolitinib (AZD6094/HMPL-504), a novel MET inhibitor, to explore extent and duration of target inhibition required for optimal efficacy in the EBC-1 mouse xenograft model

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.4263-4263

2018

Volltextzugriff (PDF)

1 – 25 von 185

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(161)
Mit Volltextzugriff
(155)

Publikationsform

1 weiteren anzeigen...

Weniger anzeigen...

Sprache

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Kollektion

Ingenta
(85)
MEDLINE
(80)
EZB*
(66)
WK Lippincott Williams & Wilkins–Connect here FIRST to enable access
(50)
Access via ScienceDirect (Elsevier)
(50)
Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)
(37)
NUS Single-Journal Subscriptions
(34)
IngentaConnect Journals
(23)
Wiley Online Library
(21)
Ebook Central Perpetual and DDA
(16)
eBooks on EBSCOhost
(16)
ScienceDirect eBooks
(16)
Oxford Journals
(11)
JSTOR
(11)
Wiley Online Library
(11)
Taylor & Francis
(11)
Nexis Uni
(10)
BMJ Journals
(10)
Access via Taylor & Francis
(10)
Taylor & Francis Journals Complete
(9)

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 30 Tagen
(1)
... seit 90 Tagen
(2)

Menü

Weitere Dienste

Einstellungen

Interspecies evaluation of a physiologically based pharmacokinetic model to predict the biodistribution dynamics of dendritic nanoparticles

PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration–time profiles in human by using the physiologically‐based pharmacokinetic modeling approach

Discovery of N‑(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)‑1H‑1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors

Quantitative Evaluation of Dendritic Nanoparticles in Mice: Biodistribution Dynamics and Downstream Tumor Efficacy Outcomes

A pharmacokinetic–pharmacodynamic model for the MET tyrosine kinase inhibitor, savolitinib, to explore target inhibition requirements for anti‐tumour activity

PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 4: Prediction of plasma concentration–time profiles in human from in vivo preclinical data by using the Wajima approach

Improving the Accuracy of Predicted Human Pharmacokinetics: Lessons Learned from the AstraZeneca Drug Pipeline Over Two Decades

Pharmacokinetic/Pharmacodynamic Analysis of Savolitinib plus Osimertinib in an EGFR Mutation-Positive, MET-Amplified Non-Small Cell Lung Cancer Model

A PKPD Case Study: Achieving Clinically Relevant Exposures of AZD5991 in Oncology Mouse Models

Post-pastoral? Rethinking religion and the reconstruction of rural space

Reduction in systolic blood pressure following dietary fibre intervention is dependent on baseline gut microbiota composition

The Pharmacokinetic-Pharmacodynamic (PKPD) Relationships of AZD3229, a Novel and Selective Inhibitor of KIT, in a Range of Mouse Xenograft Models of GIST

The MET Inhibitor AZD6094 (Savolitinib, HMPL-504) Induces Regression in Papillary Renal Cell Carcinoma Patient-Derived Xenograft Models

Applications of Quantitative Systems Pharmacology in Model‐Informed Drug Discovery: Perspective on Impact and Opportunities

Quantitative evaluation of trastuzumab deruxtecan pharmacokinetics and pharmacodynamics in mouse models of varying degrees of HER2 expression

Developing PreDICT – a fully integrated data platform for preclinical in vivo data: learning from experience

Model-based drug discovery: implementation and impact

AZD3514: a small molecule that modulates androgen receptor signaling and function in vitro and in vivo

Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer

Fuels and Fuel Technology: A Summarized Manual in Two Volumes

Novel one pot synthesis of silver nanoparticle-polymer composites by supercritical CO2 polymerisation in the presence of a RAFT agent

The discovery of indole-derived long acting β2-adrenoceptor agonists for the treatment of asthma and COPD

Further Considerations Towards an Effective and Efficient Oncology Drug Discovery DMPK Strategy

Abstract 1328: Exploring the pharmacokinetic-pharmacodynamic relationships of AZD3229, a novel and selective inhibitor of cKIT, in a range of mouse xenograft models of gastrointestinal stromal tumors

Abstract 4263: A semi-mechanistic pharmacokinetic-pharmacodynamic (PK-PD) model of savolitinib (AZD6094/HMPL-504), a novel MET inhibitor, to explore extent and duration of target inhibition required for optimal efficacy in the EBC-1 mouse xenograft model

Suchergebnisse filtern