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Phage Therapy: A Renewed Approach to Combat Antibiotic-Resistant Bacteria

Cell host & microbe, 2019-02, Vol.25 (2), p.219-232

2019

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Aging Impairs Alveolar Macrophage Phagocytosis and Increases Influenza-Induced Mortality in Mice

The Journal of immunology (1950), 2017-08, Vol.199 (3), p.1060-1068

2017

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Lytic bacteriophages induce the secretion of antiviral and proinflammatory cytokines from human respiratory epithelial cells

PLoS biology, 2024-04, Vol.22 (4), p.e3002566-e3002566

2024

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Novel Approaches to Multidrug-Resistant Infections in Cystic Fibrosis

Infectious disease clinics of North America, 2024-03, Vol.38 (1), p.149-162

2024

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Novel Approaches to Multidrug-Resistant Infections in Cystic Fibrosis

Clinics in chest medicine, 2022-12, Vol.43 (4), p.667-676

2022

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COVID-19 bacteremic co-infection is a major risk factor for mortality, ICU admission, and mechanical ventilation

Critical care (London, England), 2023-01, Vol.27 (1), p.34-12, Article 34

2023

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IFN- γ Is Protective in Cytokine Release Syndrome-associated Extrapulmonary Acute Lung Injury

American journal of respiratory cell and molecular biology, 2023-01, Vol.68 (1), p.75-89

2023

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Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation

Nature communications, 2015-02, Vol.6 (1), p.6221-6221, Article 6221

2015

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DNA Repair Interacts with Autophagy To Regulate Inflammatory Responses to Pulmonary Hyperoxia

The Journal of immunology (1950), 2017-04, Vol.198 (7), p.2844-2853

2017

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Metabolic Adaptation in Methicillin-Resistant Staphylococcus aureus Pneumonia

American journal of respiratory cell and molecular biology, 2019-08, Vol.61 (2), p.185-197

2019

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Respiratory virus-induced EGFR activation suppresses IRF1-dependent interferon λ and antiviral defense in airway epithelium

The Journal of experimental medicine, 2013-09, Vol.210 (10), p.1929-1936

2013

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Optimized preparation pipeline for emergency phage therapy against Pseudomonas aeruginosa at Yale University

Scientific reports, 2024-02, Vol.14 (1), p.2657-13, Article 2657

2024

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Bronchial epithelium epithelial-mesenchymal plasticity forms aberrant basaloid-like cells in vitro

American journal of physiology. Lung cellular and molecular physiology, 2022-06, Vol.322 (6), p.L822-L841

2022

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A neutrophil activation signature predicts critical illness and mortality in COVID-19

Blood advances, 2021-03, Vol.5 (5), p.1164-1177

2021

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Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium

American journal of physiology. Lung cellular and molecular physiology, 2008-06, Vol.294 (6), p.L1068-L1075

2008

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Phage Therapy for Respiratory Infections: Opportunities and Challenges

Lung, 2024-06, Vol.202 (3), p.223-232

2024

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Human iPSC-Based Model of COPD to Investigate Disease Mechanisms, Predict SARS-COV-2 Outcome, and Test Preventive Immunotherapy

Stem cells (Dayton, Ohio), 2024-03, Vol.42 (3), p.230-250

2024

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Amphiregulin, an Epidermal Growth Factor Receptor Ligand, Plays an Essential Role in the Pathogenesis of Transforming Growth Factor-β-induced Pulmonary Fibrosis

The Journal of biological chemistry, 2012-12, Vol.287 (50), p.41991-42000

2012

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Cystic Fibrosis

Clinics in chest medicine, 2016-03, Vol.37 (1), p.i-i

2016

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Airway microbiota and pathogen abundance in age-stratified cystic fibrosis patients

PloS one, 2010-06, Vol.5 (6), p.e11044-e11044

2010

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Ezrin links CFTR to TLR4 signaling to orchestrate anti-bacterial immune response in macrophages

Scientific reports, 2017-09, Vol.7 (1), p.10882-11, Article 10882

2017

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EGFR activation suppresses respiratory virus-induced IRF1-dependent CXCL10 production

American journal of physiology. Lung cellular and molecular physiology, 2014-07, Vol.307 (2), p.L186-L196

2014

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Cystic Fibrosis

Clinics in chest medicine, 2016-03, Vol.37 (1), p.xv-xvi

Koff, Jonathan L., MD

2016

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"Small" Intestinal Immunopathology Plays a "Big" Role in Lethal Cytokine Release Syndrome, and Its Modulation by Interferon-γ, IL-17A, and a Janus Kinase Inhibitor

Frontiers in immunology, 2020-06, Vol.11, p.1311

2020

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Epidermal Growth Factor Receptor Inhibition Is Protective in Hyperoxia-Induced Lung Injury

Oxidative medicine and cellular longevity, 2022, Vol.2022, p.9518592-18

2022

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Phage Therapy: A Renewed Approach to Combat Antibiotic-Resistant Bacteria

Aging Impairs Alveolar Macrophage Phagocytosis and Increases Influenza-Induced Mortality in Mice

Lytic bacteriophages induce the secretion of antiviral and proinflammatory cytokines from human respiratory epithelial cells

Novel Approaches to Multidrug-Resistant Infections in Cystic Fibrosis

Novel Approaches to Multidrug-Resistant Infections in Cystic Fibrosis

COVID-19 bacteremic co-infection is a major risk factor for mortality, ICU admission, and mechanical ventilation

IFN- γ Is Protective in Cytokine Release Syndrome-associated Extrapulmonary Acute Lung Injury

Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation

DNA Repair Interacts with Autophagy To Regulate Inflammatory Responses to Pulmonary Hyperoxia

Metabolic Adaptation in Methicillin-Resistant Staphylococcus aureus Pneumonia

Respiratory virus-induced EGFR activation suppresses IRF1-dependent interferon λ and antiviral defense in airway epithelium

Optimized preparation pipeline for emergency phage therapy against Pseudomonas aeruginosa at Yale University

Bronchial epithelium epithelial-mesenchymal plasticity forms aberrant basaloid-like cells in vitro

A neutrophil activation signature predicts critical illness and mortality in COVID-19

Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium

Phage Therapy for Respiratory Infections: Opportunities and Challenges

Human iPSC-Based Model of COPD to Investigate Disease Mechanisms, Predict SARS-COV-2 Outcome, and Test Preventive Immunotherapy

Amphiregulin, an Epidermal Growth Factor Receptor Ligand, Plays an Essential Role in the Pathogenesis of Transforming Growth Factor-β-induced Pulmonary Fibrosis

Cystic Fibrosis

Airway microbiota and pathogen abundance in age-stratified cystic fibrosis patients

Ezrin links CFTR to TLR4 signaling to orchestrate anti-bacterial immune response in macrophages

EGFR activation suppresses respiratory virus-induced IRF1-dependent CXCL10 production

Cystic Fibrosis

"Small" Intestinal Immunopathology Plays a "Big" Role in Lethal Cytokine Release Syndrome, and Its Modulation by Interferon-γ, IL-17A, and a Janus Kinase Inhibitor

Epidermal Growth Factor Receptor Inhibition Is Protective in Hyperoxia-Induced Lung Injury

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