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Iron activates microglia and directly stimulates indoleamine-2,3-dioxygenase activity in the N171-82Q mouse model of Huntington's disease

PloS one, 2021-05, Vol.16 (5), p.e0250606

2021

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Iron accumulates in Huntington's disease neurons: protection by deferoxamine

PloS one, 2013-10, Vol.8 (10), p.e77023-e77023

2013

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Brain mitochondrial iron accumulates in Huntington's disease, mediates mitochondrial dysfunction, and can be removed pharmacologically

Free radical biology & medicine, 2018-05, Vol.120, p.317-329

2018

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Mechanisms of copper ion mediated Huntington's disease progression

PloS one, 2007-03, Vol.2 (3), p.e334-e334

2007

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Huntingtons Disease Mice Infected with Toxoplasma gondii Demonstrate Early Kynurenine Pathway Activation, Altered CD8+ T-Cell Responses, and Premature Mortality

PloS one, 2016-09, Vol.11 (9), p.e0162404-e0162404

2016

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Altered selenium status in Huntington's disease: Neuroprotection by selenite in the N171-82Q mouse model

Neurobiology of disease, 2014-11, Vol.71, p.34-42

2014

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A Small-Molecule Therapeutic Lead for Huntington's Disease: Preclinical Pharmacology and Efficacy of C2-8 in the R6/2 Transgenic Mouse

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (42), p.16685-16689

2007

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Cysteine Oxidation within N-terminal Mutant Huntingtin Promotes Oligomerization and Delays Clearance of Soluble Protein

The Journal of biological chemistry, 2011-05, Vol.286 (20), p.18320-18330

2011

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Cellular Localization of Kynurenine 3-Monooxygenase in the Brain: Challenging the Dogma

Antioxidants, 2022-02, Vol.11 (2), p.315

2022

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Neonatal iron supplementation potentiates oxidative stress, energetic dysfunction and neurodegeneration in the R6/2 mouse model of Huntington's disease

Redox biology, 2015-04, Vol.4 (C), p.363-374

2015

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Novel proteomic changes in brain mitochondria provide insights into mitochondrial dysfunction in mouse models of Huntington's disease

Mitochondrion, 2019-07, Vol.47, p.318-329

2019

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The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease

Molecular neurodegeneration, 2010-06, Vol.5 (1), p.26-26, Article 26

2010

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Impact of high iron intake on cognition and neurodegeneration in humans and in animal models: a systematic review

Nutrition reviews, 2017-06, Vol.75 (6), p.456-470

2017

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Cystamine increases l‐cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation

Journal of neurochemistry, 2004-10, Vol.91 (2), p.413-422

2004

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Acute hepatic steatosis: a helpful diagnostic feature in metallic phosphide–poisoned horses

Journal of veterinary diagnostic investigation, 2018-03, Vol.30 (2), p.280-285

2018

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Neonatal Iron Supplementation Induces Striatal Atrophy in Female YAC128 Huntington's Disease Mice

Journal of Huntington's disease, 2016-03, Vol.5 (1), p.53-63

2016

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Amyloid Precursor Protein Haploinsufficiency Preferentially Mediates Brain Iron Accumulation in Mice Transgenic for The Huntington's Disease Mutation

Journal of Huntington's disease, 2017-01, Vol.6 (2), p.115-125

2017

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Transcriptional dysregulation in striatal projection- and interneurons in a mouse model of Huntington's disease: neuronal selectivity and potential neuroprotective role of HAP1

Human molecular genetics, 2005-01, Vol.14 (2), p.179-189

2005

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Correction: Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine

PloS one, 2013-11, Vol.8 (11)

2013

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Altered expression of transcripts for α-tubulin and an unidentified gene in the spinal cord of phenyl saligenin phosphate treated hens (Gallus gallus)

Journal of biochemical and molecular toxicology, 2003, Vol.17 (5), p.263-271

2003

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Cysteine oxidation within N-terminal mutant huntingtin promotes oligomerization and delays clearance of soluble protein

The Journal of biological chemistry, 2011-07, Vol.286 (30), p.27068-27068

2011

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γ-Diketone Peripheral Neuropathy: I. Quantitative Morphometric Analyses of Axonal Atrophy and Swelling

Toxicology and applied pharmacology, 2000-06, Vol.165 (2), p.127-140

2000

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Correction: Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine

PloS one, 2013-01, Vol.8 (11)

2013

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Vaccine associated mucosal disease case study: Demonstrating the importance of subsequent herd PI testing

The Bovine practitioner, 2013-06, p.84-93

2013

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γ-Diketone Peripheral Neuropathy

Toxicology and applied pharmacology, 2000-06, Vol.165 (2), p.127-140

2000

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Iron activates microglia and directly stimulates indoleamine-2,3-dioxygenase activity in the N171-82Q mouse model of Huntington's disease

Iron accumulates in Huntington's disease neurons: protection by deferoxamine

Brain mitochondrial iron accumulates in Huntington's disease, mediates mitochondrial dysfunction, and can be removed pharmacologically

Mechanisms of copper ion mediated Huntington's disease progression

Huntingtons Disease Mice Infected with Toxoplasma gondii Demonstrate Early Kynurenine Pathway Activation, Altered CD8+ T-Cell Responses, and Premature Mortality

Altered selenium status in Huntington's disease: Neuroprotection by selenite in the N171-82Q mouse model

A Small-Molecule Therapeutic Lead for Huntington's Disease: Preclinical Pharmacology and Efficacy of C2-8 in the R6/2 Transgenic Mouse

Cysteine Oxidation within N-terminal Mutant Huntingtin Promotes Oligomerization and Delays Clearance of Soluble Protein

Cellular Localization of Kynurenine 3-Monooxygenase in the Brain: Challenging the Dogma

Neonatal iron supplementation potentiates oxidative stress, energetic dysfunction and neurodegeneration in the R6/2 mouse model of Huntington's disease

Novel proteomic changes in brain mitochondria provide insights into mitochondrial dysfunction in mouse models of Huntington's disease

The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease

Impact of high iron intake on cognition and neurodegeneration in humans and in animal models: a systematic review

Cystamine increases l‐cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation

Acute hepatic steatosis: a helpful diagnostic feature in metallic phosphide–poisoned horses

Neonatal Iron Supplementation Induces Striatal Atrophy in Female YAC128 Huntington's Disease Mice

Amyloid Precursor Protein Haploinsufficiency Preferentially Mediates Brain Iron Accumulation in Mice Transgenic for The Huntington's Disease Mutation

Transcriptional dysregulation in striatal projection- and interneurons in a mouse model of Huntington's disease: neuronal selectivity and potential neuroprotective role of HAP1

Correction: Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine

Altered expression of transcripts for α-tubulin and an unidentified gene in the spinal cord of phenyl saligenin phosphate treated hens (Gallus gallus)

Cysteine oxidation within N-terminal mutant huntingtin promotes oligomerization and delays clearance of soluble protein

γ-Diketone Peripheral Neuropathy: I. Quantitative Morphometric Analyses of Axonal Atrophy and Swelling

Correction: Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine

Vaccine associated mucosal disease case study: Demonstrating the importance of subsequent herd PI testing

γ-Diketone Peripheral Neuropathy

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