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Troponin through the looking-glass: emerging roles beyond regulation of striated muscle contraction

Oncotarget, 2018-01, Vol.9 (1), p.1461-1482

2018

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Genotype and Cardiac Outcomes in Pediatric Dilated Cardiomyopathy

Journal of the American Heart Association, 2022-01, Vol.11 (1), p.e022854-e022854

2022

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Post-translational modification patterns on β-myosin heavy chain are altered in ischemic and nonischemic human hearts

eLife, 2022-05, Vol.11

2022

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Familial Dilated Cardiomyopathy Associated With a Novel Combination of Compound Heterozygous TNNC1 Variants

Frontiers in physiology, 2020-01, Vol.10, p.1612-1612

2020

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Precision Genetic Therapies: Balancing Risk and Benefit in Patients with Heart Failure

Current cardiology reports, 2024-09, Vol.26 (9), p.973-983

2024

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Epigenetic reprogramming to prevent genetic cardiomyopathy

The Journal of clinical investigation, 2021-01, Vol.131 (1)

2021

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Genetic correction strategies for Duchenne muscular dystrophy and their impact on the heart

Progress in pediatric cardiology, 2021-12, Vol.63, p.101460, Article 101460

2021

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Mutation location of HCM-causing troponin T mutations defines the degree of myofilament dysfunction in human cardiomyocytes

Journal of molecular and cellular cardiology, 2021-01, Vol.150, p.77-90

2021

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Structural and functional impact of troponin C-mediated Ca2+ sensitization on myofilament lattice spacing and cross-bridge mechanics in mouse cardiac muscle

Journal of molecular and cellular cardiology, 2018-10, Vol.123 (C), p.26-37

2018

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The intrinsically disordered C terminus of troponin T binds to troponin C to modulate myocardial force generation

The Journal of biological chemistry, 2019-12, Vol.294 (52), p.20054-20069

2019

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Myosin Rod Hypophosphorylation and CB Kinetics in Papillary Muscles from a TnC-A8V KI Mouse Model

Biophysical journal, 2017-04, Vol.112 (8), p.1726-1736

2017

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A comprehensive guide to genetic variants and post-translational modifications of cardiac troponin C

Journal of muscle research and cell motility, 2021-06, Vol.42 (2), p.323-342

2021

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Anomalous structural dynamics of minimally frustrated residues in cardiac troponin C triggers hypertrophic cardiomyopathy

Chemical science (Cambridge), 2021-04, Vol.12 (21), p.738-7323

2021

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Hypertrophic Cardiomyopathy Secondary to RAF1 Cysteine-Rich Domain Variants

Circulation. Genomic and precision medicine, 2023-12, Vol.16 (6), p.e004262

2023

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Epigenetic reprogramming to prevent genetic cardiomyopathy

The Journal of clinical investigation, 2021-01, Vol.131 (1), p.1-3

2021

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Genetic Variants and Post-Translational Modifications of Cardiac Troponin C: Insights from the Public Databases

Biophysical journal, 2021-02, Vol.120 (3), p.342a-342a

2021

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Location of Hypertrophic Cardiomyopathy-Causing Troponin T Mutations Determines Degree of Myofilament Dysfunction

Biophysical journal, 2018-02, Vol.114 (3), p.313a-313a

2018

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Cardiac Thin Filament-Mediated Calcium Sensitization Modulates Cross-Bridge Kinetics

Biophysical journal, 2018-02, Vol.114 (3), p.315a-316a

2018

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Structural and functional impact of troponin C-mediated Ca2+ sensitization on myofilament lattice spacing and cross-bridge mechanics in mouse cardiac muscle

Journal of molecular and cellular cardiology, 2018-10, Vol.123 (C)

2018

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Biophysical Defects Link Rare TNNC1 Variants to Cardiomyopathy

Johnston, Jamie R

2020

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Clinical and Biophysical Characterization of a Mutation in the N-Helix Region of Cardiac Troponin C: Evidence for an Allosteric Mechanism of Contractile Dysfunction

Biophysical journal, 2018-02, Vol.114 (3), p.568a-568a

2018

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Structural and functional impact of troponin C-mediated Ca 2+ sensitization on myofilament lattice spacing and cross-bridge mechanics in mouse cardiac muscle

Journal of molecular and cellular cardiology, 2018-10, Vol.123, p.26

2018

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Lost in parameter space: a road map for stacks

Methods in ecology and evolution, 2017-10, Vol.8 (10), p.1360-1373

2017

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Burden of disease from inadequate water, sanitation and hygiene in low‐ and middle‐income settings: a retrospective analysis of data from 145 countries

Tropical medicine & international health, 2014-08, Vol.19 (8), p.894-905

2014

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Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

Blood, 2013-04, Vol.121 (14), p.2659-2668

2013

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Troponin through the looking-glass: emerging roles beyond regulation of striated muscle contraction

Genotype and Cardiac Outcomes in Pediatric Dilated Cardiomyopathy

Post-translational modification patterns on β-myosin heavy chain are altered in ischemic and nonischemic human hearts

Familial Dilated Cardiomyopathy Associated With a Novel Combination of Compound Heterozygous TNNC1 Variants

Precision Genetic Therapies: Balancing Risk and Benefit in Patients with Heart Failure

Epigenetic reprogramming to prevent genetic cardiomyopathy

Genetic correction strategies for Duchenne muscular dystrophy and their impact on the heart

Mutation location of HCM-causing troponin T mutations defines the degree of myofilament dysfunction in human cardiomyocytes

Structural and functional impact of troponin C-mediated Ca2+ sensitization on myofilament lattice spacing and cross-bridge mechanics in mouse cardiac muscle

The intrinsically disordered C terminus of troponin T binds to troponin C to modulate myocardial force generation

Myosin Rod Hypophosphorylation and CB Kinetics in Papillary Muscles from a TnC-A8V KI Mouse Model

A comprehensive guide to genetic variants and post-translational modifications of cardiac troponin C

Anomalous structural dynamics of minimally frustrated residues in cardiac troponin C triggers hypertrophic cardiomyopathy

Hypertrophic Cardiomyopathy Secondary to RAF1 Cysteine-Rich Domain Variants

Epigenetic reprogramming to prevent genetic cardiomyopathy

Genetic Variants and Post-Translational Modifications of Cardiac Troponin C: Insights from the Public Databases

Location of Hypertrophic Cardiomyopathy-Causing Troponin T Mutations Determines Degree of Myofilament Dysfunction

Cardiac Thin Filament-Mediated Calcium Sensitization Modulates Cross-Bridge Kinetics

Structural and functional impact of troponin C-mediated Ca2+ sensitization on myofilament lattice spacing and cross-bridge mechanics in mouse cardiac muscle

Biophysical Defects Link Rare TNNC1 Variants to Cardiomyopathy

Clinical and Biophysical Characterization of a Mutation in the N-Helix Region of Cardiac Troponin C: Evidence for an Allosteric Mechanism of Contractile Dysfunction

Structural and functional impact of troponin C-mediated Ca 2+ sensitization on myofilament lattice spacing and cross-bridge mechanics in mouse cardiac muscle

Lost in parameter space: a road map for stacks

Burden of disease from inadequate water, sanitation and hygiene in low‐ and middle‐income settings: a retrospective analysis of data from 145 countries

Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

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