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Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions

PLoS computational biology, 2023-03, Vol.19 (3), p.e1010953-e1010953

2023

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The State of Vaccine Confidence 2016: Global Insights Through a 67-Country Survey

EBioMedicine, 2016-10, Vol.12 (C), p.295-301

2016

Volltextzugriff (PDF)

Mitochondrial Network State Scales mtDNA Genetic Dynamics

Genetics (Austin), 2019-08, Vol.212 (4), p.1429-1443

2019

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Mitochondrial Heterogeneity

Frontiers in genetics, 2019-01, Vol.9, p.718-718

2019

Volltextzugriff (PDF)

Evolution of Cell-to-Cell Variability in Stochastic, Controlled, Heteroplasmic mtDNA Populations

American journal of human genetics, 2016-11, Vol.99 (5), p.1150-1162

2016

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Evolutionary Inference across Eukaryotes Identifies Specific Pressures Favoring Mitochondrial Gene Retention

Cell systems, 2016-02, Vol.2 (2), p.101-111

2016

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Avoiding organelle mutational meltdown across eukaryotes with or without a germline bottleneck

PLoS biology, 2021-04, Vol.19 (4), p.e3001153-e3001153

2021

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Varied Mechanisms and Models for the Varying Mitochondrial Bottleneck

Frontiers in cell and developmental biology, 2019-11, Vol.7, p.294-294

Johnston, Iain G

2019

Volltextzugriff (PDF)

Large-scale genetic analysis reveals mammalian mtDNA heteroplasmy dynamics and variance increase through lifetimes and generations

Nature communications, 2018-06, Vol.9 (1), p.2488-12, Article 2488

2018

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Organelle bottlenecks facilitate evolvability by traversing heteroplasmic fitness valleys

Frontiers in genetics, 2022-10, Vol.13, p.974472-974472

2022

Volltextzugriff (PDF)

Energetic costs of cellular and therapeutic control of stochastic mitochondrial DNA populations

PLoS computational biology, 2019-06, Vol.15 (6), p.e1007023-e1007023

2019

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mtDNA Segregation in Heteroplasmic Tissues Is Common In Vivo and Modulated by Haplotype Differences and Developmental Stage

Cell reports (Cambridge), 2014-06, Vol.7 (6), p.2031-2041

2014

Volltextzugriff (PDF)

Tension and Resolution: Dynamic, Evolving Populations of Organelle Genomes within Plant Cells

Molecular plant, 2019-06, Vol.12 (6), p.764-783

Johnston, Iain G.

2019

Volltextzugriff (PDF)

Forecasted trends in vaccination coverage and correlations with socioeconomic factors: a global time-series analysis over 30 years

The Lancet global health, 2016-10, Vol.4 (10), p.e726-e735

2016

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Pulsing of Membrane Potential in Individual Mitochondria: A Stress-Induced Mechanism to Regulate Respiratory Bioenergetics in Arabidopsis

The Plant cell, 2012-03, Vol.24 (3), p.1188-1201

2012

Volltextzugriff (PDF)

Sexually antagonistic evolution of mitochondrial and nuclear linkage

Journal of evolutionary biology, 2021-05, Vol.34 (5), p.757-766

2021

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Mitochondrial variability as a source of extrinsic cellular noise

PLoS computational biology, 2012-03, Vol.8 (3), p.e1002416-e1002416

2012

Volltextzugriff (PDF)

2-Deoxy-D-glucose couples mitochondrial DNA replication with mitochondrial fitness and promotes the selection of wild-type over mutant mitochondrial DNA

Nature communications, 2021-12, Vol.12 (1), p.6997-6997, Article 6997

2021

Volltextzugriff (PDF)

Stochastic modelling, Bayesian inference, and new in vivo measurements elucidate the debated mtDNA bottleneck mechanism

eLife, 2015-06, Vol.4, p.e07464-e07464

2015

Volltextzugriff (PDF)

Avoiding misleading estimates using mtDNA heteroplasmy statistics to study bottleneck size and selection

G3 : genes - genomes - genetics, 2023-06, Vol.13 (6)

2023

Volltextzugriff (PDF)

Optimal strategies in the fighting fantasy gaming system: Influencing stochastic dynamics by gambling with limited resource

European journal of operational research, 2022-11, Vol.302 (3), p.1272-1281

Johnston, Iain G.

2022

Volltextzugriff (PDF)

Understanding learner behaviour in online courses with Bayesian modelling and time series characterisation

Scientific reports, 2021-02, Vol.11 (1), p.2823-2823, Article 2823

2021

Volltextzugriff (PDF)

Data science approaches provide a roadmap to understanding the role of abscisic acid in defence

Quantitative plant biology, 2023, Vol.4, p.e2-e2, Article e2

2023

Volltextzugriff (PDF)

Comparing Structure and Dynamics of Transition Graphs by the Symmetric Difference Metric Over an Edge-Filtration

IEEE access, 2024, Vol.12, p.81030-81046

2024

Volltextzugriff (PDF)

Evolution and maintenance of mtDNA gene content across eukaryotes

Biochemical journal, 2024-08, Vol.481 (15), p.1015-1042

2024

Volltextzugriff (PDF)

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Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions

The State of Vaccine Confidence 2016: Global Insights Through a 67-Country Survey

Mitochondrial Network State Scales mtDNA Genetic Dynamics

Mitochondrial Heterogeneity

Evolution of Cell-to-Cell Variability in Stochastic, Controlled, Heteroplasmic mtDNA Populations

Evolutionary Inference across Eukaryotes Identifies Specific Pressures Favoring Mitochondrial Gene Retention

Avoiding organelle mutational meltdown across eukaryotes with or without a germline bottleneck

Varied Mechanisms and Models for the Varying Mitochondrial Bottleneck

Large-scale genetic analysis reveals mammalian mtDNA heteroplasmy dynamics and variance increase through lifetimes and generations

Organelle bottlenecks facilitate evolvability by traversing heteroplasmic fitness valleys

Energetic costs of cellular and therapeutic control of stochastic mitochondrial DNA populations

mtDNA Segregation in Heteroplasmic Tissues Is Common In Vivo and Modulated by Haplotype Differences and Developmental Stage

Tension and Resolution: Dynamic, Evolving Populations of Organelle Genomes within Plant Cells

Forecasted trends in vaccination coverage and correlations with socioeconomic factors: a global time-series analysis over 30 years

Pulsing of Membrane Potential in Individual Mitochondria: A Stress-Induced Mechanism to Regulate Respiratory Bioenergetics in Arabidopsis

Sexually antagonistic evolution of mitochondrial and nuclear linkage

Mitochondrial variability as a source of extrinsic cellular noise

2-Deoxy-D-glucose couples mitochondrial DNA replication with mitochondrial fitness and promotes the selection of wild-type over mutant mitochondrial DNA

Stochastic modelling, Bayesian inference, and new in vivo measurements elucidate the debated mtDNA bottleneck mechanism

Avoiding misleading estimates using mtDNA heteroplasmy statistics to study bottleneck size and selection

Optimal strategies in the fighting fantasy gaming system: Influencing stochastic dynamics by gambling with limited resource

Understanding learner behaviour in online courses with Bayesian modelling and time series characterisation

Data science approaches provide a roadmap to understanding the role of abscisic acid in defence

Comparing Structure and Dynamics of Transition Graphs by the Symmetric Difference Metric Over an Edge-Filtration

Evolution and maintenance of mtDNA gene content across eukaryotes

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