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Quantitative High-Throughput Screening: A Titration-Based Approach That Efficiently Identifies Biological Activities in Large Chemical Libraries

Proceedings of the National Academy of Sciences - PNAS, 2006-08, Vol.103 (31), p.11473-11478

2006

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High-throughput screening assays for the identification of chemical probes

Nature chemical biology, 2007-08, Vol.3 (8), p.466-479

2007

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Characterization of Chemical Libraries for Luciferase Inhibitory Activity

Journal of medicinal chemistry, 2008-04, Vol.51 (8), p.2372-2386

2008

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Ras signalling on the endoplasmic reticulum and the Golgi

Nature cell biology, 2002-05, Vol.4 (5), p.343-350

2002

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Identification of Aminothienopyridazine Inhibitors of Tau Assembly by Quantitative High-Throughput Screening

Biochemistry (Easton), 2009-08, Vol.48 (32), p.7732-7745

2009

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A Class of Tricyclic Compounds Blocking Malaria Parasite Oocyst Development and Transmission

Antimicrobial Agents and Chemotherapy, 2013-01, Vol.57 (1), p.425-435

2013

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Differentiating Alzheimer disease-associated aggregates with small molecules

Neurobiology of disease, 2007-12, Vol.28 (3), p.251-260

2007

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High Affinity for Farnesyltransferase and Alternative Prenylation Contribute Individually to K-Ras4B Resistance to Farnesyltransferase Inhibitors

The Journal of biological chemistry, 2003-10, Vol.278 (43), p.41718-41727

2003

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Discovery of new antimalarial chemotypes through chemical methodology and library development

Proceedings of the National Academy of Sciences - PNAS, 2011-04, Vol.108 (17), p.6775-6780

2011

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How do land-use practices affect human—elephant conflict in nepal?

Wildlife Biology, 2017-01, Vol.2017 (4), p.1-9

2017

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The C-terminal Tails of Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) and Fas Receptors Have Opposing Functions in Fas-associated Death Domain (FADD) Recruitment and Can Regulate Agonist-specific Mechanisms of Receptor Activation

The Journal of biological chemistry, 2004-12, Vol.279 (50), p.52479-52486

2004

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Evaluation of the GENE-UP® Salmonella Method for the Detection of Salmonella Species in a Broad Range of Foods and Select Environmental Surfaces: Collaborative Study, First Action 2020.02

Journal of AOAC International, 2021-08, Vol.104 (4), p.1084-1097

2021

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The National Cancer Institute and Cannabis and Cannabinoids Research

Journal of the National Cancer Institute. Monographs, 2021-11, Vol.2021 (58), p.35-38

2021

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Chemical Genomic Profiling for Antimalarial Therapies, Response Signatures, and Molecular Targets

Science (American Association for the Advancement of Science), 2011-08, Vol.333 (6043), p.724-729

2011

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Changes in habitat suitability over a two decade period before and after Asian elephant recolonization

Global ecology and conservation, 2020-06, Vol.22, p.e01023, Article e01023

2020

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Habitat use by Asian elephants: Context matters

Global ecology and conservation, 2019-01, Vol.17, p.e00570, Article e00570

2019

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Several PATCHED1 Missense Mutations Display Activity in patched1-Deficient Fibroblasts

The Journal of biological chemistry, 2002-09, Vol.277 (37), p.33632-33640

2002

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Identification of Potent and Selective Diphenylpropanamide RORγ Inhibitors

ACS medicinal chemistry letters, 2013-01, Vol.4 (1), p.79-84

2013

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Matrix Positivity

Johnson, Charles R

1, 2020

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Methylsulfonylnitrobenzoates, a New Class of Irreversible Inhibitors of the Interaction of the Thyroid Hormone Receptor and Its Obligate Coactivators That Functionally Antagonizes Thyroid Hormone

The Journal of biological chemistry, 2011-04, Vol.286 (14), p.11895-11908

2011

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Human Homolog of patched, a Candidate Gene for the Basal Cell Nevus Syndrome

Science (American Association for the Advancement of Science), 1996-06, Vol.272 (5268), p.1668-1671

1996

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A distinct class of dominant negative Ras mutants: cytosolic GTP-bound Ras effector domain mutants that inhibit Ras signaling and transformation and enhance cell adhesion

The Journal of biological chemistry, 2002-03, Vol.277 (13), p.10813-10823

2002

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An image-based, high-throughput screening assay for molecules that induce excess DNA replication in human cancer cells

Molecular cancer research, 2011-03, Vol.9 (3), p.294-310

2011

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Genetic structure of the polychaete Nereis grubei in the context of current patterns and life history

Marine ecology. Progress series (Halstenbek), 2013-01, Vol.473, p.215-224

2013

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The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

Nature (London), 1996-11, Vol.384 (6605), p.129-134

1996

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Quantitative High-Throughput Screening: A Titration-Based Approach That Efficiently Identifies Biological Activities in Large Chemical Libraries

High-throughput screening assays for the identification of chemical probes

Characterization of Chemical Libraries for Luciferase Inhibitory Activity

Ras signalling on the endoplasmic reticulum and the Golgi

Identification of Aminothienopyridazine Inhibitors of Tau Assembly by Quantitative High-Throughput Screening

A Class of Tricyclic Compounds Blocking Malaria Parasite Oocyst Development and Transmission

Differentiating Alzheimer disease-associated aggregates with small molecules

High Affinity for Farnesyltransferase and Alternative Prenylation Contribute Individually to K-Ras4B Resistance to Farnesyltransferase Inhibitors

Discovery of new antimalarial chemotypes through chemical methodology and library development

How do land-use practices affect human—elephant conflict in nepal?

The C-terminal Tails of Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) and Fas Receptors Have Opposing Functions in Fas-associated Death Domain (FADD) Recruitment and Can Regulate Agonist-specific Mechanisms of Receptor Activation

Evaluation of the GENE-UP® Salmonella Method for the Detection of Salmonella Species in a Broad Range of Foods and Select Environmental Surfaces: Collaborative Study, First Action 2020.02

The National Cancer Institute and Cannabis and Cannabinoids Research

Chemical Genomic Profiling for Antimalarial Therapies, Response Signatures, and Molecular Targets

Changes in habitat suitability over a two decade period before and after Asian elephant recolonization

Habitat use by Asian elephants: Context matters

Several PATCHED1 Missense Mutations Display Activity in patched1-Deficient Fibroblasts

Identification of Potent and Selective Diphenylpropanamide RORγ Inhibitors

Matrix Positivity

Methylsulfonylnitrobenzoates, a New Class of Irreversible Inhibitors of the Interaction of the Thyroid Hormone Receptor and Its Obligate Coactivators That Functionally Antagonizes Thyroid Hormone

Human Homolog of patched, a Candidate Gene for the Basal Cell Nevus Syndrome

A distinct class of dominant negative Ras mutants: cytosolic GTP-bound Ras effector domain mutants that inhibit Ras signaling and transformation and enhance cell adhesion

An image-based, high-throughput screening assay for molecules that induce excess DNA replication in human cancer cells

Genetic structure of the polychaete Nereis grubei in the context of current patterns and life history

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

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