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Polyfunctional T-cell responses are disrupted by the ovarian cancer ascites environment and only partially restored by clinically relevant cytokines

PloS one, 2010-12, Vol.5 (12), p.e15625-e15625

2010

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Transfusion management in the era of magrolimab (Hu5F9‐G4), an anti‐CD47 monoclonal antibody therapy

Transfusion (Philadelphia, Pa.), 2023-12, Vol.63 (12), p.2377-2383

2023

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TGF-β sensitivity restrains CD8+ T cell homeostatic proliferation by enforcing sensitivity to IL-7 and IL-15

PloS one, 2012-08, Vol.7 (8), p.e42268-e42268

2012

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Quantification of a proteotypic peptide from protein C inhibitor by liquid chromatography-free SISCAPA-MALDI mass spectrometry: application to identification of recurrence of prostate cancer

Clinical chemistry (Baltimore, Md.), 2013-10, Vol.59 (10), p.1514-1522

2013

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A Chronic Need for IL-21

Science (American Association for the Advancement of Science), 2009-06, Vol.324 (5934), p.1525-1526

2009

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Phase I Study of the CD47 Blocker TTI-621 in Patients with Relapsed or Refractory Hematologic Malignancies

Clinical cancer research, 2021-04, Vol.27 (8), p.2190-2199

2021

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The antigen-specific CD8+ T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion

The Journal of experimental medicine, 2009-02, Vol.206 (2), p.435-448

2009

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The pivotal role of cytotoxic NK cells in mediating the therapeutic effect of anti-CD47 therapy in mycosis fungoides

Cancer Immunology, Immunotherapy, 2022-04, Vol.71 (4), p.919-932

2022

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Negative regulators in homeostasis of naïve peripheral T cells

Immunologic research, 2008-06, Vol.41 (2), p.137-153

2008

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Targeting CD47 in Sézary syndrome with SIRPαFc

Blood advances, 2019-04, Vol.3 (7), p.1145-1153

2019

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Histidine rich glycoprotein and cancer: a multi-faceted relationship

Anticancer research, 2014-02, Vol.34 (2), p.593-603

2014

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Self-specific CD8+ T cells maintain a semi-naive state following lymphopenia-induced proliferation

The Journal of immunology (1950), 2010-05, Vol.184 (10), p.5604-5611

2010

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TGF-[beta] Sensitivity Restrains CD8+ T Cell Homeostatic Proliferation by Enforcing Sensitivity to IL-7 and IL-15

PloS one, 2012-08, Vol.7 (8), p.e42268

2012

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Abstract 2345: SIRPαFc, a CD47-blocking cancer immunotherapeutic, triggers phagocytosis of lymphoma cells by both classically (M1) and alternatively (M2) activated macrophages

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2345-2345

2016

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Intralesional Administration of the CD47 Antagonist TTI-621 (SIRPαFc) Induces Responses in Both Injected and Non-Injected Lesions in Patients with Relapsed/Refractory Mycosis Fungoides and Sézary Syndrome: Interim Results of a Multicenter Phase I Trial

Blood, 2018-11, Vol.132 (Supplement 1), p.1653-1653

2018

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Intralesional Injection of the CD47-blocking immune checkpoint inhibitor TTI-621 (SIRPaFc) induces antitumor activity in patients with relapsed/refractory mycosis fungoides and Sézary syndrome: Interim results of a multicenter Phase 1 trial

European journal of cancer (1990), 2018-09, Vol.101, p.S34-S34

2018

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A Single Direct Intratumoral Injection of TTI-621 (SIRPαFc) Induces Antitumor Activity in Patients with Relapsed/Refractory Mycosis Fungoides and Sézary Syndrome: Preliminary Findings Employing an Immune Checkpoint Inhibitor Blocking the CD47 “Do Not Eat” Signal

Blood, 2017-12, Vol.130, p.4076-4076

2017

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TTI-621 (SIRPαFc), an Immune Checkpoint Inhibitor Blocking the CD47 “Do Not Eat” Signal, Induces Objective Responses in Patients with Advanced, Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

Blood, 2017-12, Vol.130, p.4116-4116

2017

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A Phase 1 Study of TTI-621, a Novel Immune Checkpoint Inhibitor Targeting CD47, in Patients with Relapsed or Refractory Hematologic Malignancies

Blood, 2016-12, Vol.128 (22), p.1812-1812

2016

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Abstract 2345: SIRPFc, a CD47-blocking cancer immunotherapeutic, triggers phagocytosis of lymphoma cells by both classically (M1) and alternatively (M2) activated macrophages

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2345-2345

2016

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Tumor-associated autoantibodies correlate with poor outcome in prostate cancer patients treated with androgen deprivation and external beam radiation therapy

Oncoimmunology, 2014-06, Vol.3 (6), p.e29243-e29243

2014

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Abstract B51: Synergistic effects of αCTLA-4 and radiotherapy in the treatment of prostate cancer

Cancer research (Chicago, Ill.), 2013-01, Vol.73 (1_Supplement), p.B51-B51

2013

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Immunology. A chronic need for IL-21

Science (American Association for the Advancement of Science), 2009-06, Vol.324 (5934), p.1525-1526

2009

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Tumor-associated autoantibodies correlate with poor outcome in prostate cancer patients treated with androgen deprivation and external beam radiation therapy

OncoImmunology, 2014, Vol.3 (6)

2014

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Real-time sequence-validated loop-mediated isothermal amplification assays for detection of Middle East respiratory syndrome coronavirus (MERS-CoV)

PloS one, 2015-04, Vol.10 (4), p.e0123126-e0123126

2015

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Polyfunctional T-cell responses are disrupted by the ovarian cancer ascites environment and only partially restored by clinically relevant cytokines

Transfusion management in the era of magrolimab (Hu5F9‐G4), an anti‐CD47 monoclonal antibody therapy

TGF-β sensitivity restrains CD8+ T cell homeostatic proliferation by enforcing sensitivity to IL-7 and IL-15

Quantification of a proteotypic peptide from protein C inhibitor by liquid chromatography-free SISCAPA-MALDI mass spectrometry: application to identification of recurrence of prostate cancer

A Chronic Need for IL-21

Phase I Study of the CD47 Blocker TTI-621 in Patients with Relapsed or Refractory Hematologic Malignancies

The antigen-specific CD8+ T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion

The pivotal role of cytotoxic NK cells in mediating the therapeutic effect of anti-CD47 therapy in mycosis fungoides

Negative regulators in homeostasis of naïve peripheral T cells

Targeting CD47 in Sézary syndrome with SIRPαFc

Histidine rich glycoprotein and cancer: a multi-faceted relationship

Self-specific CD8+ T cells maintain a semi-naive state following lymphopenia-induced proliferation

TGF-[beta] Sensitivity Restrains CD8+ T Cell Homeostatic Proliferation by Enforcing Sensitivity to IL-7 and IL-15

Abstract 2345: SIRPαFc, a CD47-blocking cancer immunotherapeutic, triggers phagocytosis of lymphoma cells by both classically (M1) and alternatively (M2) activated macrophages

Intralesional Administration of the CD47 Antagonist TTI-621 (SIRPαFc) Induces Responses in Both Injected and Non-Injected Lesions in Patients with Relapsed/Refractory Mycosis Fungoides and Sézary Syndrome: Interim Results of a Multicenter Phase I Trial

Intralesional Injection of the CD47-blocking immune checkpoint inhibitor TTI-621 (SIRPaFc) induces antitumor activity in patients with relapsed/refractory mycosis fungoides and Sézary syndrome: Interim results of a multicenter Phase 1 trial

A Single Direct Intratumoral Injection of TTI-621 (SIRPαFc) Induces Antitumor Activity in Patients with Relapsed/Refractory Mycosis Fungoides and Sézary Syndrome: Preliminary Findings Employing an Immune Checkpoint Inhibitor Blocking the CD47 “Do Not Eat” Signal

TTI-621 (SIRPαFc), an Immune Checkpoint Inhibitor Blocking the CD47 “Do Not Eat” Signal, Induces Objective Responses in Patients with Advanced, Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

A Phase 1 Study of TTI-621, a Novel Immune Checkpoint Inhibitor Targeting CD47, in Patients with Relapsed or Refractory Hematologic Malignancies

Abstract 2345: SIRPFc, a CD47-blocking cancer immunotherapeutic, triggers phagocytosis of lymphoma cells by both classically (M1) and alternatively (M2) activated macrophages

Tumor-associated autoantibodies correlate with poor outcome in prostate cancer patients treated with androgen deprivation and external beam radiation therapy

Abstract B51: Synergistic effects of αCTLA-4 and radiotherapy in the treatment of prostate cancer

Immunology. A chronic need for IL-21

Tumor-associated autoantibodies correlate with poor outcome in prostate cancer patients treated with androgen deprivation and external beam radiation therapy

Real-time sequence-validated loop-mediated isothermal amplification assays for detection of Middle East respiratory syndrome coronavirus (MERS-CoV)

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