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Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 1: Where have we been and what have we learned?

Neurobiology of disease, 2017-01, Vol.97 (Pt B), p.156-168

2017

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Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 2: Where do we stand and where must we go next?

Neurobiology of disease, 2017-01, Vol.97 (Pt B), p.169-178

2017

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Bioactivity of AAV2-neurturin gene therapy (CERE-120): Differences between Parkinson's disease and nonhuman primate brains

Movement disorders, 2011-01, Vol.26 (1), p.27-36

2011

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Lipid rafts in neuronal signaling and function

Trends in Neurosciences, 2002-08, Vol.25 (8), p.412-417

2002

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Critical and distinct roles for key RET tyrosine docking sites in renal development

Genes & development, 2006-02, Vol.20 (3), p.321-333

2006

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Transplantation of embryonic stem cells overexpressing Bcl-2 promotes functional recovery after transient cerebral ischemia

Neurobiology of disease, 2005-06, Vol.19 (1), p.183-193

2005

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RET Signaling Is Required for Survival and Normal Function of Nonpeptidergic Nociceptors

The Journal of neuroscience, 2010-03, Vol.30 (11), p.3983-3994

2010

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JNK-Mediated BIM Phosphorylation Potentiates BAX-Dependent Apoptosis

Neuron (Cambridge, Mass.), 2003-06, Vol.38 (6), p.899-914

2003

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RET Is Dispensable for Maintenance of Midbrain Dopaminergic Neurons in Adult Mice

The Journal of neuroscience, 2006-10, Vol.26 (43), p.11230-11238

2006

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Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120)

Neurobiology of disease, 2013-10, Vol.58, p.38-48

2013

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Properly scaled and targeted AAV2-NRTN (neurturin) to the substantia nigra is safe, effective and causes no weight loss: Support for nigral targeting in Parkinson's disease

Neurobiology of disease, 2011-10, Vol.44 (1), p.38-52

2011

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BH3-only Bcl-2 Family Members Are Coordinately Regulated by the JNK Pathway and Require Bax to Induce Apoptosis in Neurons

The Journal of biological chemistry, 2001-10, Vol.276 (41), p.37754-37760

2001

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Glial Cell Line-Derived Neurotrophic Factor-Dependent Recruitment of Ret into Lipid Rafts Enhances Signaling by Partitioning Ret from Proteasome-Dependent Degradation

The Journal of neuroscience, 2006-03, Vol.26 (10), p.2777-2787

2006

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Artemin Is a Vascular-Derived Neurotropic Factor for Developing Sympathetic Neurons

Neuron (Cambridge, Mass.), 2002-07, Vol.35 (2), p.267-282

2002

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Mice expressing a dominant-negative Ret mutation phenocopy human Hirschsprung disease and delineate a direct role of Ret in spermatogenesis

Development (Cambridge), 2004-11, Vol.131 (21), p.5503-5513

2004

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Mixed-lineage kinases: A target for the prevention of neurodegeneration

Annual review of pharmacology and toxicology, 2004-01, Vol.44 (1), p.451-474

2004

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The GDNF family ligands and receptors — implications for neural development

Current Opinion in Neurobiology, 2000-02, Vol.10 (1), p.103-110

2000

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Dopamine-dependent compensation maintains motor behavior in mice with developmental ablation of dopaminergic neurons

The Journal of neuroscience, 2013-10, Vol.33 (43), p.17095-17107

2013

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Induction of BIM, a Proapoptotic BH3-Only BCL-2 Family Member, Is Critical for Neuronal Apoptosis

Neuron (Cambridge, Mass.), 2001-03, Vol.29 (3), p.615-628

2001

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RET signaling is essential for migration, axonal growth and axon guidance of developing sympathetic neurons

Development (Cambridge), 2001-10, Vol.128 (20), p.3963-3974

2001

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Neurturin-Mediated Ret Activation Is Required for Retinal Function

The Journal of neuroscience, 2008-04, Vol.28 (16), p.4123-4135

2008

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Dok-6, a Novel p62 Dok Family Member, Promotes Ret-mediated Neurite Outgrowth

The Journal of biological chemistry, 2004-10, Vol.279 (40), p.42072-42081

2004

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Neurturin, a relative of glial-cell-line-derived neurotrophic factor

Nature (London), 1996-12, Vol.384 (6608), p.467-470

1996

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Disruption of the Jak1 Gene Demonstrates Obligatory and Nonredundant Roles of the Jaks in Cytokine-Induced Biologic Responses

Cell, 1998-05, Vol.93 (3), p.373-383

1998

Volltextzugriff (PDF)

Tyrosine 981, a Novel Ret Autophosphorylation Site, Binds c-Src to Mediate Neuronal Survival

The Journal of biological chemistry, 2004-04, Vol.279 (18), p.18262-18269

2004

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Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 1: Where have we been and what have we learned?

Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 2: Where do we stand and where must we go next?

Bioactivity of AAV2-neurturin gene therapy (CERE-120): Differences between Parkinson's disease and nonhuman primate brains

Lipid rafts in neuronal signaling and function

Critical and distinct roles for key RET tyrosine docking sites in renal development

Transplantation of embryonic stem cells overexpressing Bcl-2 promotes functional recovery after transient cerebral ischemia

RET Signaling Is Required for Survival and Normal Function of Nonpeptidergic Nociceptors

JNK-Mediated BIM Phosphorylation Potentiates BAX-Dependent Apoptosis

RET Is Dispensable for Maintenance of Midbrain Dopaminergic Neurons in Adult Mice

Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120)

Properly scaled and targeted AAV2-NRTN (neurturin) to the substantia nigra is safe, effective and causes no weight loss: Support for nigral targeting in Parkinson's disease

BH3-only Bcl-2 Family Members Are Coordinately Regulated by the JNK Pathway and Require Bax to Induce Apoptosis in Neurons

Glial Cell Line-Derived Neurotrophic Factor-Dependent Recruitment of Ret into Lipid Rafts Enhances Signaling by Partitioning Ret from Proteasome-Dependent Degradation

Artemin Is a Vascular-Derived Neurotropic Factor for Developing Sympathetic Neurons

Mice expressing a dominant-negative Ret mutation phenocopy human Hirschsprung disease and delineate a direct role of Ret in spermatogenesis

Mixed-lineage kinases: A target for the prevention of neurodegeneration

The GDNF family ligands and receptors — implications for neural development

Dopamine-dependent compensation maintains motor behavior in mice with developmental ablation of dopaminergic neurons

Induction of BIM, a Proapoptotic BH3-Only BCL-2 Family Member, Is Critical for Neuronal Apoptosis

RET signaling is essential for migration, axonal growth and axon guidance of developing sympathetic neurons

Neurturin-Mediated Ret Activation Is Required for Retinal Function

Dok-6, a Novel p62 Dok Family Member, Promotes Ret-mediated Neurite Outgrowth

Neurturin, a relative of glial-cell-line-derived neurotrophic factor

Disruption of the Jak1 Gene Demonstrates Obligatory and Nonredundant Roles of the Jaks in Cytokine-Induced Biologic Responses

Tyrosine 981, a Novel Ret Autophosphorylation Site, Binds c-Src to Mediate Neuronal Survival

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