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Structural diversity of human xenobiotic-metabolizing cytochrome P450 monooxygenases

Biochemical and biophysical research communications, 2005-12, Vol.338 (1), p.331-336

2005

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[6] Yeast expression of animal and plant P450s in optimized redox environments

Methods in Enzymology, 1996, Vol.272, p.51-64

1996

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Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen

Nature structural & molecular biology, 2005-09, Vol.12 (9), p.822-823

2005

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The Structure of Human Cytochrome P450 2C9 Complexed with Flurbiprofen at 2.0-Ã Resolution

The Journal of biological chemistry, 2004-08, Vol.279 (34), p.35630-35637

2004

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Mammalian Microsomal Cytochrome P450 Monooxygenase: Structural Adaptations for Membrane Binding and Functional Diversity

Molecular cell, 2000, Vol.5 (1), p.121-131

2000

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Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain

Proceedings of the National Academy of Sciences - PNAS, 2008-07, Vol.105 (28), p.9546-9551

2008

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[42] Use of human hepatocytes to study P450 gene induction

Methods in Enzymology, 1996, Vol.272, p.388-401

1996

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Histological and metabolism analysis of P450 expression in the brain

Methods in Enzymology, 2002, Vol.357, p.241-249

2002

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[22] CYP2D6 multiallelism

Methods in Enzymology, 1996, Vol.272, p.199-210

1996

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[5] Application of electrochemistry for P450-catalyzed reactions

Methods in Enzymology, 1996, Vol.272, p.44-51

1996

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Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo

Molecular cancer therapeutics, 2005-06, Vol.4 (6), p.977-986

2005

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Preclinical activity of ABT-869, a multitargeted receptor tyrosine kinase inhibitor

Molecular cancer therapeutics, 2006-04, Vol.5 (4), p.995-1006

2006

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Cryoradiolysis for the study of P450 reaction intermediates

Methods in Enzymology, 2002, Vol.357, p.103-115

2002

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Genotyping human CYP2A6 variants

Methods in Enzymology, 2002, Vol.357, p.59-69

2002

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The CYP4A Isoforms Hydroxylate Epoxyeicosatrienoic Acids to Form High Affinity Peroxisome Proliferator-activated Receptor Ligands

The Journal of biological chemistry, 2002-09, Vol.277 (38), p.35105-35112

2002

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Sequence alignments, variabilities, and vagaries

Methods in Enzymology, 2002, Vol.357, p.15-28

2002

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Cytochrome P450, Part C

1, 2002

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[35] Structural alignments of P450s and extrapolations to the unknown

Methods in Enzymology, 1996, Vol.272, p.315-326

1996

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The 2002 Bernard B. Brodie Award lecture: deciphering substrate recognition by drug-metabolizing cytochromes P450

Drug metabolism and disposition, 2003-12, Vol.31 (12), p.1532-1540

Johnson, Eric F

2003

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[1] Maximizing expression of eukaryotic cytochrome P450s in Escherichia coli

Methods in Enzymology, 1996, Vol.272, p.3-14

Barnes, Henry J.

1996

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Peroxisome proliferator activated receptor-alpha expression in human liver

Molecular pharmacology, 1998-01, Vol.53 (1), p.14-22

1998

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Discovery and SAR of orally efficacious tetrahydropyridopyridazinone PARP inhibitors for the treatment of cancer

Bioorganic & medicinal chemistry, 2012-08, Vol.20 (15), p.4635-4645

2012

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Optical biosensor and scanning probe microscopy studies of cytochrome P450 interactions with redox partners and phospholipid layers

Methods in Enzymology, 2002, Vol.357, p.94-103

2002

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Use of methylotropic yeast Pichia, pastoris for expression of cytochromes P450

Methods in Enzymology, 2002, Vol.357, p.333-342

2002

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Partial recoding of P450 and P450 reductase cDNAs for improved expression in yeast and plants

Cytochrome P450 Part C, 2002, Vol.357, p.343-351

2002

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Structural diversity of human xenobiotic-metabolizing cytochrome P450 monooxygenases

[6] Yeast expression of animal and plant P450s in optimized redox environments

Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen

The Structure of Human Cytochrome P450 2C9 Complexed with Flurbiprofen at 2.0-Ã Resolution

Mammalian Microsomal Cytochrome P450 Monooxygenase: Structural Adaptations for Membrane Binding and Functional Diversity

Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain

[42] Use of human hepatocytes to study P450 gene induction

Histological and metabolism analysis of P450 expression in the brain

[22] CYP2D6 multiallelism

[5] Application of electrochemistry for P450-catalyzed reactions

Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo

Preclinical activity of ABT-869, a multitargeted receptor tyrosine kinase inhibitor

Cryoradiolysis for the study of P450 reaction intermediates

Genotyping human CYP2A6 variants

The CYP4A Isoforms Hydroxylate Epoxyeicosatrienoic Acids to Form High Affinity Peroxisome Proliferator-activated Receptor Ligands

Sequence alignments, variabilities, and vagaries

Cytochrome P450, Part C

[35] Structural alignments of P450s and extrapolations to the unknown

The 2002 Bernard B. Brodie Award lecture: deciphering substrate recognition by drug-metabolizing cytochromes P450

[1] Maximizing expression of eukaryotic cytochrome P450s in Escherichia coli

Peroxisome proliferator activated receptor-alpha expression in human liver

Discovery and SAR of orally efficacious tetrahydropyridopyridazinone PARP inhibitors for the treatment of cancer

Optical biosensor and scanning probe microscopy studies of cytochrome P450 interactions with redox partners and phospholipid layers

Use of methylotropic yeast Pichia, pastoris for expression of cytochromes P450

Partial recoding of P450 and P450 reductase cDNAs for improved expression in yeast and plants

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