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DeltaNp63-dependent super enhancers define molecular identity in pancreatic cancer by an interconnected transcription factor network

Proceedings of the National Academy of Sciences - PNAS, 2018-12, Vol.115 (52), p.E12343-E12352

2018

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The enigmatic role of H2Bub1 in cancer

FEBS letters, 2012-06, Vol.586 (11), p.1592-1601

Johnsen, Steven A.

2012

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USP22 exerts tumor-suppressive functions in colorectal cancer by decreasing mTOR activity

Cell death and differentiation, 2020-04, Vol.27 (4), p.1328-1340

2020

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The Histone H2B Monoubiquitination Regulatory Pathway Is Required for Differentiation of Multipotent Stem Cells

Molecular cell, 2012-06, Vol.46 (5), p.705-713

2012

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Bromodomain Protein BRD4 Is Required for Estrogen Receptor-Dependent Enhancer Activation and Gene Transcription

Cell reports (Cambridge), 2014-07, Vol.8 (2), p.460-469

2014

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Stem-Cell-like Properties and Epithelial Plasticity Arise as Stable Traits after Transient Twist1 Activation

Cell reports (Cambridge), 2015-01, Vol.10 (2), p.131-139

2015

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USP22 promotes HER2-driven mammary carcinoma aggressiveness by suppressing the unfolded protein response

Oncogene, 2021-06, Vol.40 (23), p.4004-4018

2021

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Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis

Nature communications, 2021-07, Vol.12 (1), p.4560-14, Article 4560

2021

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Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness

EMBO reports, 2016-11, Vol.17 (11), p.1609-1623

2016

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SAGA-Dependent Histone H2Bub1 Deubiquitination Is Essential for Cellular Ubiquitin Balance during Embryonic Development

International journal of molecular sciences, 2022-07, Vol.23 (13), p.7459

2022

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Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4- and MYC-dependent manner

Nucleic acids research, 2017-06, Vol.45 (11), p.6334-6349

2017

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The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene

American journal of physiology: endocrinology and metabolism, 2008-10, Vol.295 (4), p.E785-E797

2008

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Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination

Nucleic acids research, 2020-09, Vol.48 (16), p.8959-8976

2020

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Estrogen-Dependent Gene Transcription in Human Breast Cancer Cells Relies upon Proteasome-Dependent Monoubiquitination of Histone H2B

Cancer research (Chicago, Ill.), 2011-09, Vol.71 (17), p.5739-5753

2011

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NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar–Ductal Transdifferentiation in the Pancreas

Gastroenterology (New York, N.Y. 1943), 2015-05, Vol.148 (5), p.1024-1034.e9

2015

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RNF40 epigenetically modulates glycolysis to support the aggressiveness of basal-like breast cancer

Cell death & disease, 2023-09, Vol.14 (9), p.641-641, Article 641

2023

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The H2B ubiquitin ligase RNF40 cooperates with SUPT16H to induce dynamic changes in chromatin structure during DNA double-strand break repair

Cell cycle (Georgetown, Tex.), 2011-10, Vol.10 (20), p.3495-3504

2011

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The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression

Genes & development, 2008-10, Vol.22 (19), p.2664-2676

2008

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USP22 supports the aggressive behavior of basal-like breast cancer by stimulating cellular respiration

Cell communication and signaling, 2024-02, Vol.22 (1), p.120-120, Article 120

2024

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SIRT2 directs the replication stress response through CDK9 deacetylation

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (33), p.13546-13551

2013

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CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 3′-end processing

EMBO reports, 2009-08, Vol.10 (8), p.894-900

2009

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Targeted therapy of epigenomic regulatory mechanisms controlling the epithelial to mesenchymal transition during tumor progression

Cell and tissue research, 2014-06, Vol.356 (3), p.617-630

2014

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Phosphorylation by cyclin-dependent kinase-9 controls ubiquitin-conjugating enzyme-2A function

Cell cycle (Georgetown, Tex.), 2012-06, Vol.11 (11), p.2122-2127

2012

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The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness

Clinical epigenetics, 2019-01, Vol.11 (1), p.4-4, Article 4

2019

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Af9/Mllt3 interferes with Tbr1 expression through epigenetic modification of histone H3K79 during development of the cerebral cortex

Proceedings of the National Academy of Sciences - PNAS, 2010-04, Vol.107 (15), p.7042-7047

2010

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DeltaNp63-dependent super enhancers define molecular identity in pancreatic cancer by an interconnected transcription factor network

The enigmatic role of H2Bub1 in cancer

USP22 exerts tumor-suppressive functions in colorectal cancer by decreasing mTOR activity

The Histone H2B Monoubiquitination Regulatory Pathway Is Required for Differentiation of Multipotent Stem Cells

Bromodomain Protein BRD4 Is Required for Estrogen Receptor-Dependent Enhancer Activation and Gene Transcription

Stem-Cell-like Properties and Epithelial Plasticity Arise as Stable Traits after Transient Twist1 Activation

USP22 promotes HER2-driven mammary carcinoma aggressiveness by suppressing the unfolded protein response

Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis

Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness

SAGA-Dependent Histone H2Bub1 Deubiquitination Is Essential for Cellular Ubiquitin Balance during Embryonic Development

Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4- and MYC-dependent manner

The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene

Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination

Estrogen-Dependent Gene Transcription in Human Breast Cancer Cells Relies upon Proteasome-Dependent Monoubiquitination of Histone H2B

NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar–Ductal Transdifferentiation in the Pancreas

RNF40 epigenetically modulates glycolysis to support the aggressiveness of basal-like breast cancer

The H2B ubiquitin ligase RNF40 cooperates with SUPT16H to induce dynamic changes in chromatin structure during DNA double-strand break repair

The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression

USP22 supports the aggressive behavior of basal-like breast cancer by stimulating cellular respiration

SIRT2 directs the replication stress response through CDK9 deacetylation

CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 3′-end processing

Targeted therapy of epigenomic regulatory mechanisms controlling the epithelial to mesenchymal transition during tumor progression

Phosphorylation by cyclin-dependent kinase-9 controls ubiquitin-conjugating enzyme-2A function

The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness

Af9/Mllt3 interferes with Tbr1 expression through epigenetic modification of histone H3K79 during development of the cerebral cortex

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