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Immunological aspects of intestinal mucus and mucins

Nature reviews. Immunology, 2016-10, Vol.16 (10), p.639-649

2016

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The role of goblet cells and mucus in intestinal homeostasis

Nature reviews. Gastroenterology & hepatology, 2022-12, Vol.19 (12), p.785-803

2022

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Fast renewal of the distal colonic mucus layers by the surface goblet cells as measured by in vivo labeling of mucin glycoproteins

PloS one, 2012-07, Vol.7 (7), p.e41009

2012

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two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (Supplement 1), p.4659-4665

2011

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The gastrointestinal mucus system in health and disease

Nature reviews. Gastroenterology & hepatology, 2013-06, Vol.10 (6), p.352-361

2013

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Bacteria penetrate the inner mucus layer before inflammation in the dextran sulfate colitis model

PloS one, 2010-08, Vol.5 (8), p.e12238

2010

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inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (39), p.15064-15069

2008

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An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function

Science (American Association for the Advancement of Science), 2021-04, Vol.372 (6539)

2021

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A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion

Science (American Association for the Advancement of Science), 2016-06, Vol.352 (6293), p.1535-1542

2016

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Goblet cells need some stress

The Journal of clinical investigation, 2022-09, Vol.132 (17), p.1-3

2022

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Calcium and pH-dependent packing and release of the gel-forming MUC2 mucin

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (15), p.5645-5650

2012

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Bifidobacteria or Fiber Protects against Diet-Induced Microbiota-Mediated Colonic Mucus Deterioration

Cell host & microbe, 2018-01, Vol.23 (1), p.27-40.e7

2018

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Altered mucus glycosylation in core 1 O-glycan-deficient mice affects microbiota composition and intestinal architecture

PloS one, 2014-01, Vol.9 (1), p.e85254

2014

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Structural weakening of the colonic mucus barrier is an early event in ulcerative colitis pathogenesis

Gut, 2019-12, Vol.68 (12), p.2142-2151

2019

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Normalization of Host Intestinal Mucus Layers Requires Long-Term Microbial Colonization

Cell host & microbe, 2015-11, Vol.18 (5), p.582-592

2015

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The composition of the gut microbiota shapes the colon mucus barrier

EMBO reports, 2015-02, Vol.16 (2), p.164-177

2015

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Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis

Gut, 2014-02, Vol.63 (2), p.281-291

2014

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Study of mucin turnover in the small intestine by in vivo labeling

Scientific reports, 2018-04, Vol.8 (1), p.5760-11, Article 5760

2018

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Potential roles of gut microbiome and metabolites in modulating ALS in mice

Nature (London), 2019-08, Vol.572 (7770), p.474-480

2019

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Composition and functional role of the mucus layers in the intestine

Cellular and molecular life sciences : CMLS, 2011-11, Vol.68 (22), p.3635-3641

2011

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Spontaneous colitis in Muc2-deficient mice reflects clinical and cellular features of active ulcerative colitis

PloS one, 2014-06, Vol.9 (6), p.e100217-e100217

2014

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Extended Photo-Conversion Spectrum in Low-Toxic Bismuth Halide Perovskite Solar Cells

The journal of physical chemistry letters, 2016-09, Vol.7 (17), p.3467-3471

2016

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Transglutaminase 3 crosslinks the secreted gel-forming mucus component Mucin-2 and stabilizes the colonic mucus layer

Nature communications, 2022-01, Vol.13 (1), p.45-45, Article 45

2022

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The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system

Immunological reviews, 2014-07, Vol.260 (1), p.8-20

2014

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Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16

Proceedings of the National Academy of Sciences - PNAS, 2016-11, Vol.113 (48), p.13833-13838

2016

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Immunological aspects of intestinal mucus and mucins

The role of goblet cells and mucus in intestinal homeostasis

Fast renewal of the distal colonic mucus layers by the surface goblet cells as measured by in vivo labeling of mucin glycoproteins

two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions

The gastrointestinal mucus system in health and disease

Bacteria penetrate the inner mucus layer before inflammation in the dextran sulfate colitis model

inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function

A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion

Goblet cells need some stress

Calcium and pH-dependent packing and release of the gel-forming MUC2 mucin

Bifidobacteria or Fiber Protects against Diet-Induced Microbiota-Mediated Colonic Mucus Deterioration

Altered mucus glycosylation in core 1 O-glycan-deficient mice affects microbiota composition and intestinal architecture

Structural weakening of the colonic mucus barrier is an early event in ulcerative colitis pathogenesis

Normalization of Host Intestinal Mucus Layers Requires Long-Term Microbial Colonization

The composition of the gut microbiota shapes the colon mucus barrier

Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis

Study of mucin turnover in the small intestine by in vivo labeling

Potential roles of gut microbiome and metabolites in modulating ALS in mice

Composition and functional role of the mucus layers in the intestine

Spontaneous colitis in Muc2-deficient mice reflects clinical and cellular features of active ulcerative colitis

Extended Photo-Conversion Spectrum in Low-Toxic Bismuth Halide Perovskite Solar Cells

Transglutaminase 3 crosslinks the secreted gel-forming mucus component Mucin-2 and stabilizes the colonic mucus layer

The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system

Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16

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