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Identification and characterization of small molecule inhibitors of the LINE-1 retrotransposon endonuclease

Nature communications, 2024-05, Vol.15 (1), p.3883-3883, Article 3883

2024

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Allosteric Motions of the CRISPR–Cas9 HNH Nuclease Probed by NMR and Molecular Dynamics

Journal of the American Chemical Society, 2020-01, Vol.142 (3), p.1348-1358

2020

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Phase separation of the LINE-1 ORF1 protein is mediated by the N-terminus and coiled-coil domain

Biophysical journal, 2021-06, Vol.120 (11), p.2181-2191

2021

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Structural and Biochemical Studies of TIGAR (TP53-induced Glycolysis and Apoptosis Regulator)

The Journal of biological chemistry, 2009-01, Vol.284 (3), p.1748-1754

2009

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The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism

Journal of the American Chemical Society, 2016-09, Vol.138 (38), p.12678-12689

2016

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Disruption of electrostatic contacts in the HNH nuclease from a thermophilic Cas9 rewires allosteric motions and enhances high-temperature DNA cleavage

The Journal of chemical physics, 2022-12, Vol.157 (22), p.225103-225103

2022

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A structural basis for streptomycin-induced misreading of the genetic code

Nature communications, 2013-01, Vol.4 (1), p.1355-1355, Article 1355

2013

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Cryo-electron microscopy structure of the 70S ribosome from Enterococcus faecalis

Scientific reports, 2020-10, Vol.10 (1), p.16301-16301, Article 16301

2020

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Expansion of GA Dinucleotide Repeats Increases the Density of CLAMP Binding Sites on the X-Chromosome to Promote Drosophila Dosage Compensation

PLoS genetics, 2016-07, Vol.12 (7), p.e1006120-e1006120

2016

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Crystal Structure of Carnitine Acetyltransferase and Implications for the Catalytic Mechanism and Fatty Acid Transport

Cell, 2003-01, Vol.112 (1), p.113-122

2003

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Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function

RNA (Cambridge), 2010-12, Vol.16 (12), p.2319-2324

2010

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The central role of protein S12 in organizing the structure of the decoding site of the ribosome

RNA (Cambridge), 2013-12, Vol.19 (12), p.1791-1801

2013

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Crystal Structure of Inositol Phosphate Multikinase 2 and Implications for Substrate Specificity

The Journal of biological chemistry, 2006-12, Vol.281 (49), p.38109-38116

2006

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Tiamulin-Resistant Mutants of the Thermophilic Bacterium Thermus thermophilus

Antibiotics (Basel), 2020-06, Vol.9 (6), p.313

2020

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A Survey of Spontaneous Antibiotic-Resistant Mutants of the Halophilic, Thermophilic Bacterium Rhodothermus marinus

Antibiotics (Basel), 2021-11, Vol.10 (11), p.1384

2021

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Structure and Function of Carnitine Acyltransferases

Annals of the New York Academy of Sciences, 2004-11, Vol.1033 (1), p.17-29

2004

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Optimal Alignment for Enzymatic Proton Transfer: Structure of the Michaelis Complex of Triosephosphate Isomerase at 1.2-Å Resolution

Proceedings of the National Academy of Sciences - PNAS, 2003-01, Vol.100 (1), p.50-55

2003

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High-resolution neutron crystallographic studies of the hydration of the coenzyme cob(II)alamin

Acta crystallographica. Section D, Biological crystallography., 2011-06, Vol.67 (6), p.584-591

2011

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Crystal structure of rat carnitine palmitoyltransferase II (CPT-II)

Biochemical and biophysical research communications, 2006-08, Vol.346 (3), p.974-980

2006

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Crystal Structure of the Non-heme Iron Dioxygenase PtlH in Pentalenolactone Biosynthesis

The Journal of biological chemistry, 2007-12, Vol.282 (50), p.36552-36560

2007

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Crystal Structure of the Thermus thermophilus 16 S rRNA Methyltransferase RsmC in Complex with Cofactor and Substrate Guanosine

The Journal of biological chemistry, 2008-09, Vol.283 (39), p.26548-26556

2008

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Unique structural and dynamic properties of the HNH nuclease in mesophilic and thermophilic Cas9 revealed by NMR

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA

The EMBO journal, 2007-01, Vol.26 (2), p.567-577

2007

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Crystal Structures of Murine Carnitine Acetyltransferase in Ternary Complexes with Its Substrates

The Journal of biological chemistry, 2006-09, Vol.281 (38), p.28480-28487

2006

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Crystal Structure of Mouse Carnitine Octanoyltransferase and Molecular Determinants of Substrate Selectivity[boxs]

The Journal of biological chemistry, 2005-01, Vol.280 (1), p.738-744

2005

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Identification and characterization of small molecule inhibitors of the LINE-1 retrotransposon endonuclease

Allosteric Motions of the CRISPR–Cas9 HNH Nuclease Probed by NMR and Molecular Dynamics

Phase separation of the LINE-1 ORF1 protein is mediated by the N-terminus and coiled-coil domain

Structural and Biochemical Studies of TIGAR (TP53-induced Glycolysis and Apoptosis Regulator)

The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism

Disruption of electrostatic contacts in the HNH nuclease from a thermophilic Cas9 rewires allosteric motions and enhances high-temperature DNA cleavage

A structural basis for streptomycin-induced misreading of the genetic code

Cryo-electron microscopy structure of the 70S ribosome from Enterococcus faecalis

Expansion of GA Dinucleotide Repeats Increases the Density of CLAMP Binding Sites on the X-Chromosome to Promote Drosophila Dosage Compensation

Crystal Structure of Carnitine Acetyltransferase and Implications for the Catalytic Mechanism and Fatty Acid Transport

Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function

The central role of protein S12 in organizing the structure of the decoding site of the ribosome

Crystal Structure of Inositol Phosphate Multikinase 2 and Implications for Substrate Specificity

Tiamulin-Resistant Mutants of the Thermophilic Bacterium Thermus thermophilus

A Survey of Spontaneous Antibiotic-Resistant Mutants of the Halophilic, Thermophilic Bacterium Rhodothermus marinus

Structure and Function of Carnitine Acyltransferases

Optimal Alignment for Enzymatic Proton Transfer: Structure of the Michaelis Complex of Triosephosphate Isomerase at 1.2-Å Resolution

High-resolution neutron crystallographic studies of the hydration of the coenzyme cob(II)alamin

Crystal structure of rat carnitine palmitoyltransferase II (CPT-II)

Crystal Structure of the Non-heme Iron Dioxygenase PtlH in Pentalenolactone Biosynthesis

Crystal Structure of the Thermus thermophilus 16 S rRNA Methyltransferase RsmC in Complex with Cofactor and Substrate Guanosine

Unique structural and dynamic properties of the HNH nuclease in mesophilic and thermophilic Cas9 revealed by NMR

Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA

Crystal Structures of Murine Carnitine Acetyltransferase in Ternary Complexes with Its Substrates

Crystal Structure of Mouse Carnitine Octanoyltransferase and Molecular Determinants of Substrate Selectivity[boxs]

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