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Cellular inhibition of checkpoint kinase 2 (Chk2) and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 [7-nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide]

The Journal of pharmacology and experimental therapeutics, 2009-12, Vol.331 (3), p.816-826

2009

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Inhibition of Human Tyrosyl-DNA Phosphodiesterase by Aminoglycoside Antibiotics and Ribosome Inhibitors

Molecular pharmacology, 2006-07, Vol.70 (1), p.366-372

2006

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Identification of a Bis-guanylhydrazone [4,4â²-Diacetyldiphenylurea-bis(guanylhydrazone); NSC 109555] as a Novel Chemotype for Inhibition of Chk2 Kinase

Molecular pharmacology, 2007-10, Vol.72 (4), p.876-884

2007

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Structural characterization of inhibitor complexes with checkpoint kinase 2 (Chk2), a drug target for cancer therapy

Journal of structural biology, 2011-12, Vol.176 (3), p.292-301

2011

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Detection of in Vitro Kinase Generated Protein Phosphorylation Sites Using γ[18O4]-ATP and Mass Spectrometry

Analytical chemistry (Washington), 2007-10, Vol.79 (20), p.7603-7610

2007

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X-ray structures of checkpoint kinase 2 in complex with inhibitors that target its gatekeeper-dependent hydrophobic pocket

FEBS letters, 2011-10, Vol.585 (20), p.3245-3249

2011

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Crystal structure of checkpoint kinase 2 in complex with NSC 109555, a potent and selective inhibitor

Protein science, 2009-01, Vol.18 (1), p.92-100

2009

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Effect of phenazine compounds XR11576 and XR5944 on DNA topoisomerases

Cancer chemotherapy and pharmacology, 2009-04, Vol.63 (5), p.889-901

2009

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Curcumin Induces High Levels of Topoisomerase I− and II−DNA Complexes in K562 Leukemia Cells

Journal of natural products (Washington, D.C.), 2007-12, Vol.70 (12), p.1884-1888

2007

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Repair of Topoisomerase I‐Mediated DNA Damage

Progress in Nucleic Acid Research and Molecular Biology, 2006, Vol.81, p.179-229

2006

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Detection of in Vitro Kinase Generated Protein Phosphorylation Sites Using ¿[^sup 18^O^sub 4^]-ATP and Mass Spectrometry

Analytical chemistry (Washington), 2007-10, Vol.79 (20), p.7603

2007

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Abstract A205: Chk2 status (activation, proteomic, gene, and exon expression) and insights into the activity of its inhibitor PV1019 across the 60 cell lines from the NCI Screen

Molecular cancer therapeutics, 2009-12, Vol.8 (12_Supplement), p.A205-A205

2009

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Detection of in vitro kinase generated protein phosphorylation sites using γ[18O]-ATP anand mass spectrometry

Analytical chemistry (Washington), 2007, Vol.79 (20), p.7603-7610

2007

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Abstract A120: Cellular inhibition of Chk2 kinase and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019

Molecular cancer therapeutics, 2009-12, Vol.8 (12_Supplement), p.A120-A120

2009

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Some considerations of the thermodynamics and kinetics of the chemical vapour deposition of tungsten

Applied surface science, 1989-09, Vol.38 (1), p.312-337

1989

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The role of the medial prefrontal cortex in cognition, ageing and dementia

Brain communications, 2021-07, Vol.3 (3), p.fcab125-fcab125

2021

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Addition of anaerobic electron acceptors to solid media did not enhance growth of 125 spacecraft bacteria under simulated low-pressure Martian conditions

Scientific reports, 2020-10, Vol.10 (1), p.18290-18290, Article 18290

2020

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A higher effort-based paradigm in physical activity and exercise for public health: making the case for a greater emphasis on resistance training

BMC public health, 2017-04, Vol.17 (1), p.300-300, Article 300

2017

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Nine new species of Australian Nicotiana (Solanaceae)

Australian systematic botany, 2023-07, Vol.36 (3), p.167-205

2023

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Reliability of oscillometric central blood pressure and central systolic loading in individuals over 50 years: Effects of posture and fasting

Atherosclerosis, 2018-02, Vol.269, p.79-85

2018

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Oscillometric central blood pressure and central systolic loading in stroke patients: Short-term reproducibility and effects of posture and fasting state

PloS one, 2018-11, Vol.13 (11), p.e0206329-e0206329

2018

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Correction: Oscillometric central blood pressure and central systolic loading in stroke patients: Short-term reproducibility and effects of posture and fasting state

PloS one, 2018-11, Vol.13 (11), p.e0208477-e0208477

2018

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Distribution Coefficient Model for Zirconium and Technetium Extraction from Nitric Acid Solution

Industrial & engineering chemistry research, 2022-01, Vol.61 (1), p.786-804

2022

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Application of SAFT-VRE in the Flowsheet Simulation of an Advanced PUREX Process

Industrial & engineering chemistry research, 2019-03, Vol.58 (9), p.3822-3831

2019

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Identification and molecular characterization of novel Rht‐1 alleles in hard red spring wheat

Crop science, 2021-03, Vol.61 (2), p.1030-1037

2021

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Cellular inhibition of checkpoint kinase 2 (Chk2) and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 [7-nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide]

Inhibition of Human Tyrosyl-DNA Phosphodiesterase by Aminoglycoside Antibiotics and Ribosome Inhibitors

Identification of a Bis-guanylhydrazone [4,4â²-Diacetyldiphenylurea-bis(guanylhydrazone); NSC 109555] as a Novel Chemotype for Inhibition of Chk2 Kinase

Structural characterization of inhibitor complexes with checkpoint kinase 2 (Chk2), a drug target for cancer therapy

Detection of in Vitro Kinase Generated Protein Phosphorylation Sites Using γ[18O4]-ATP and Mass Spectrometry

X-ray structures of checkpoint kinase 2 in complex with inhibitors that target its gatekeeper-dependent hydrophobic pocket

Crystal structure of checkpoint kinase 2 in complex with NSC 109555, a potent and selective inhibitor

Effect of phenazine compounds XR11576 and XR5944 on DNA topoisomerases

Curcumin Induces High Levels of Topoisomerase I− and II−DNA Complexes in K562 Leukemia Cells

Repair of Topoisomerase I‐Mediated DNA Damage

Detection of in Vitro Kinase Generated Protein Phosphorylation Sites Using ¿[^sup 18^O^sub 4^]-ATP and Mass Spectrometry

Abstract A205: Chk2 status (activation, proteomic, gene, and exon expression) and insights into the activity of its inhibitor PV1019 across the 60 cell lines from the NCI Screen

Detection of in vitro kinase generated protein phosphorylation sites using γ[18O]-ATP anand mass spectrometry

Abstract A120: Cellular inhibition of Chk2 kinase and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019

Some considerations of the thermodynamics and kinetics of the chemical vapour deposition of tungsten

The role of the medial prefrontal cortex in cognition, ageing and dementia

Addition of anaerobic electron acceptors to solid media did not enhance growth of 125 spacecraft bacteria under simulated low-pressure Martian conditions

A higher effort-based paradigm in physical activity and exercise for public health: making the case for a greater emphasis on resistance training

Nine new species of Australian Nicotiana (Solanaceae)

Reliability of oscillometric central blood pressure and central systolic loading in individuals over 50 years: Effects of posture and fasting

Oscillometric central blood pressure and central systolic loading in stroke patients: Short-term reproducibility and effects of posture and fasting state

Correction: Oscillometric central blood pressure and central systolic loading in stroke patients: Short-term reproducibility and effects of posture and fasting state

Distribution Coefficient Model for Zirconium and Technetium Extraction from Nitric Acid Solution

Application of SAFT-VRE in the Flowsheet Simulation of an Advanced PUREX Process

Identification and molecular characterization of novel Rht‐1 alleles in hard red spring wheat

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