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Prime editing efficiency and fidelity are enhanced in the absence of mismatch repair

Nature communications, 2022-02, Vol.13 (1), p.760-760, Article 760

2022

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Postreplicative mismatch repair

Cold Spring Harbor perspectives in biology, 2013-04, Vol.5 (4), p.a012633-a012633

Jiricny, Josef

2013

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Biochemical characterization of a cancer-associated E109K missense variant of human exonuclease 1

Nucleic acids research, 2014-06, Vol.42 (11), p.7096

2014

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Replication errors: cha(lle)nging the genome

The EMBO journal, 1998-11, Vol.17 (22), p.6427-6436

Jiricny, Josef

1998

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Epigenetic silencing of monoallelically methylated miRNA loci in precancerous colorectal lesions

Oncogenesis (New York, NY), 2013-07, Vol.2 (7), p.e56-e56

2013

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A new class of uracil-DNA glycosylases related to human thymine-DNA glycosylase

Nature (London), 1996-10, Vol.383 (6602), p.735-738

1996

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Unique mutational profile associated with a loss of TDG expression in the rectal cancer of a patient with a constitutional PMS2 deficiency

DNA repair, 2012-07, Vol.11 (7), p.616-623

2012

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Separating Substrate Recognition from Base Hydrolysis in Human Thymine DNA Glycosylase by Mutational Analysis

The Journal of biological chemistry, 2000-10, Vol.275 (43), p.33449-33456

2000

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The purification of a mismatch-specific thymine-DNA glycosylase from HeLa cells

The Journal of biological chemistry, 1993-10, Vol.268 (28), p.21218-21224

1993

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Mismatch repair and DNA damage signalling

DNA Repair, 2004-08, Vol.3 (8), p.1091-1101

2004

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Colon cancer and DNA repair: have mismatches met their match?

Trends in Genetics, 1994-05, Vol.10 (5), p.164-168

Jiricny, Josef

1994

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Mismatch-Specific Thymine DNA Glycosylase and DNA Polymerase β Mediate the Correction of G.T Mispairs in Nuclear Extracts from Human Cells

Proceedings of the National Academy of Sciences - PNAS, 1990-08, Vol.87 (15), p.5842-5845

1990

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Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover

The EMBO journal, 2002-03, Vol.21 (6), p.1456-1464

2002

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The Bloom's Syndrome Helicase Interacts Directly with the Human DNA Mismatch Repair Protein hMSH6

Biological chemistry, 2003-08, Vol.384 (8), p.1155-1164

2003

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DNA Cytosine Demethylation: Are We Getting Close?

Cell, 2008-12, Vol.135 (7), p.1167-1169

2008

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Human RECQ5β, a protein with DNA helicase and strand-annealing activities in a single polypeptide

The EMBO journal, 2004-07, Vol.23 (14), p.2882-2891

2004

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Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated

Genes & development, 1988-09, Vol.2 (9), p.1127-1135

1988

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Mismatch repair and cancer

Cancer surveys, 1996, Vol.28, p.47

Jiricny, J

1996

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Recent progress in the biology, chemistry and structural biology of DNA glycosylases

BioEssays, 2001-03, Vol.23 (3), p.270-281

2001

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Mismatch repair defects in cancer

Current Opinion in Genetics & Development, 2000-04, Vol.10 (2), p.157-161

2000

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Dependence of the cytotoxicity of DNA-damaging agents on the mismatch repair status of human cells

Cancer research (Chicago, Ill.), 2004-05, Vol.64 (10), p.3391-3394

2004

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The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

Nature (London), 1999-09, Vol.401 (6750), p.301-304

1999

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Immunohistochemical Analysis Reveals High Frequency of PMS2 Defects in Colorectal Cancer

Gastroenterology (New York, N.Y. 1943), 2005-05, Vol.128 (5), p.1160-1171

2005

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DNA Damage Induced by Temozolomide Signals to both ATM and ATR: Role of the Mismatch Repair System

Molecular pharmacology, 2004-09, Vol.66 (3), p.478-491

2004

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Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair

Cancer research (Chicago, Ill.), 2005-12, Vol.65 (23), p.10759-10766

2005

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Prime editing efficiency and fidelity are enhanced in the absence of mismatch repair

Postreplicative mismatch repair

Biochemical characterization of a cancer-associated E109K missense variant of human exonuclease 1

Replication errors: cha(lle)nging the genome

Epigenetic silencing of monoallelically methylated miRNA loci in precancerous colorectal lesions

A new class of uracil-DNA glycosylases related to human thymine-DNA glycosylase

Unique mutational profile associated with a loss of TDG expression in the rectal cancer of a patient with a constitutional PMS2 deficiency

Separating Substrate Recognition from Base Hydrolysis in Human Thymine DNA Glycosylase by Mutational Analysis

The purification of a mismatch-specific thymine-DNA glycosylase from HeLa cells

Mismatch repair and DNA damage signalling

Colon cancer and DNA repair: have mismatches met their match?

Mismatch-Specific Thymine DNA Glycosylase and DNA Polymerase β Mediate the Correction of G.T Mispairs in Nuclear Extracts from Human Cells

Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover

The Bloom's Syndrome Helicase Interacts Directly with the Human DNA Mismatch Repair Protein hMSH6

DNA Cytosine Demethylation: Are We Getting Close?

Human RECQ5β, a protein with DNA helicase and strand-annealing activities in a single polypeptide

Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated

Mismatch repair and cancer

Recent progress in the biology, chemistry and structural biology of DNA glycosylases

Mismatch repair defects in cancer

Dependence of the cytotoxicity of DNA-damaging agents on the mismatch repair status of human cells

The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

Immunohistochemical Analysis Reveals High Frequency of PMS2 Defects in Colorectal Cancer

DNA Damage Induced by Temozolomide Signals to both ATM and ATR: Role of the Mismatch Repair System

Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair

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