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AKT and ERK dual inhibitors: The way forward?

Cancer letters, 2019-09, Vol.459, p.30-40

2019

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Human alkaline ceramidase 2 promotes the growth, invasion, and migration of hepatocellular carcinoma cells via sphingomyelin phosphodiesterase acid‐like 3B

Cancer science, 2020-07, Vol.111 (7), p.2259-2274

2020

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Ubiquitination of UVRAG by SMURF1 promotes autophagosome maturation and inhibits hepatocellular carcinoma growth

Autophagy, 2019-07, Vol.15 (7), p.1130-1149

2019

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A completeness-independent method for pre-selection of closely related genomes for species delineation in prokaryotes

BMC genomics, 2020-02, Vol.21 (1), p.183-183, Article 183

2020

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Ceramide kinase-mediated C1P metabolism attenuates acute liver injury by inhibiting the interaction between KEAP1 and NRF2

Experimental and Molecular Medicine, 2024, 56(0), , pp.946-958

2024

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Editorial: Sphingolipid metabolism dysfunction in cancer

Frontiers in endocrinology (Lausanne), 2023-06, Vol.14, p.1208616-1208616

2023

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Bcl-2 and Bcl-xL mediate resistance to receptor tyrosine kinase-targeted therapy in lung and gastric cancer

Anti-cancer drugs, 2017-11, Vol.28 (10), p.1141-1149

2017

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S1PR1 induces metabolic reprogramming of ceramide in vascular endothelial cells, affecting hepatocellular carcinoma angiogenesis and progression

Cell death & disease, 2022-09, Vol.13 (9), p.768-15, Article 768

2022

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Targeting CLK3 inhibits the progression of cholangiocarcinoma by reprogramming nucleotide metabolism

The Journal of experimental medicine, 2020-08, Vol.217 (8)

2020

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Mogroside IIE Inhibits Digestive Enzymes via Suppression of Interleukin 9/Interleukin 9 Receptor Signalling in Acute Pancreatitis

Frontiers in pharmacology, 2020-06, Vol.11, p.859-859

2020

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A high-resolution genomic composition-based method with the ability to distinguish similar bacterial organisms

BMC genomics, 2019-10, Vol.20 (1), p.754-754, Article 754

2019

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LPS and palmitate synergistically stimulate sphingosine kinase 1 and increase sphingosine 1 phosphate in RAW264.7 macrophages

Journal of leukocyte biology, 2018-10, Vol.104 (4), p.843-853

2018

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Natural immunoglobulin M initiates an inflammatory response important for both hepatic ischemia reperfusion injury and regeneration in mice

Hepatology (Baltimore, Md.), 2018-02, Vol.67 (2), p.721-735

2018

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Integrative transcriptomic and proteomics profiling analyses reveals PLK1 as a target of curcumol in hepatocellular carcinoma cells

Journal of functional foods, 2023-11, Vol.110, p.105834, Article 105834

2023

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Lipopolysaccharide and palmitic acid synergistically induced MCP-1 production via MAPK-meditated TLR4 signaling pathway in RAW264.7 cells

Lipids in health and disease, 2019-03, Vol.18 (1), p.71-9, Article 71

2019

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Trabid inhibits hepatocellular carcinoma growth and metastasis by cleaving RNF8-induced K63 ubiquitination of Twist1

Cell death and differentiation, 2019-02, Vol.26 (2), p.306-320

2019

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Docosahexaenoic acid antagonizes the boosting effect of palmitic acid on LPS inflammatory signaling by inhibiting gene transcription and ceramide synthesis

PloS one, 2018-02, Vol.13 (2), p.e0193343

2018

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Proteomic analysis of small extracellular vesicles from the plasma of patients with hepatocellular carcinoma

World journal of surgical oncology, 2022-12, Vol.20 (1), p.387-387, Article 387

2022

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Acid sphingomyelinase plays a key role in palmitic acid-amplified inflammatory signaling triggered by lipopolysaccharide at low concentrations in macrophages

American journal of physiology: endocrinology and metabolism, 2013-10, Vol.305 (7), p.E853-E867

2013

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Pulmonary interleukin 1 beta/serum amyloid A3 axis promotes lung metastasis of hepatocellular carcinoma by facilitating the pre-metastatic niche formation

Journal of experimental & clinical cancer research, 2023-07, Vol.42 (1), p.166-166, Article 166

2023

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GBA1-dependent membrane glucosylceramide reprogramming promotes liver cancer metastasis via activation of the Wnt/β-catenin signalling pathway

Cell death & disease, 2022-05, Vol.13 (5), p.508-508, Article 508

2022

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Neutral ceramidase activity inhibition is involved in palmitate-induced apoptosis in INS-1 cells

Endocrine Journal, 2017, Vol.64(8), pp.767-776

2017

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Serum sphingosine negatively correlates with albumin predicting the risk of hepatocellular carcinoma

Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia, 2020-06, Vol.164 (2), p.203-208

2020

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C1orf74 positively regulates the EGFR/AKT/mTORC1 signaling in lung adenocarcinoma cells

PeerJ (San Francisco, CA), 2022-08, Vol.10, p.e13908-e13908, Article e13908

2022

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Characterization of Novel P-Selectin Targeted Complement Inhibitors in Murine Models of Hindlimb Injury and Transplantation

Frontiers in immunology, 2021-11, Vol.12, p.785229

2021

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AKT and ERK dual inhibitors: The way forward?

Human alkaline ceramidase 2 promotes the growth, invasion, and migration of hepatocellular carcinoma cells via sphingomyelin phosphodiesterase acid‐like 3B

Ubiquitination of UVRAG by SMURF1 promotes autophagosome maturation and inhibits hepatocellular carcinoma growth

A completeness-independent method for pre-selection of closely related genomes for species delineation in prokaryotes

Ceramide kinase-mediated C1P metabolism attenuates acute liver injury by inhibiting the interaction between KEAP1 and NRF2

Editorial: Sphingolipid metabolism dysfunction in cancer

Bcl-2 and Bcl-xL mediate resistance to receptor tyrosine kinase-targeted therapy in lung and gastric cancer

S1PR1 induces metabolic reprogramming of ceramide in vascular endothelial cells, affecting hepatocellular carcinoma angiogenesis and progression

Targeting CLK3 inhibits the progression of cholangiocarcinoma by reprogramming nucleotide metabolism

Mogroside IIE Inhibits Digestive Enzymes via Suppression of Interleukin 9/Interleukin 9 Receptor Signalling in Acute Pancreatitis

A high-resolution genomic composition-based method with the ability to distinguish similar bacterial organisms

LPS and palmitate synergistically stimulate sphingosine kinase 1 and increase sphingosine 1 phosphate in RAW264.7 macrophages

Natural immunoglobulin M initiates an inflammatory response important for both hepatic ischemia reperfusion injury and regeneration in mice

Integrative transcriptomic and proteomics profiling analyses reveals PLK1 as a target of curcumol in hepatocellular carcinoma cells

Lipopolysaccharide and palmitic acid synergistically induced MCP-1 production via MAPK-meditated TLR4 signaling pathway in RAW264.7 cells

Trabid inhibits hepatocellular carcinoma growth and metastasis by cleaving RNF8-induced K63 ubiquitination of Twist1

Docosahexaenoic acid antagonizes the boosting effect of palmitic acid on LPS inflammatory signaling by inhibiting gene transcription and ceramide synthesis

Proteomic analysis of small extracellular vesicles from the plasma of patients with hepatocellular carcinoma

Acid sphingomyelinase plays a key role in palmitic acid-amplified inflammatory signaling triggered by lipopolysaccharide at low concentrations in macrophages

Pulmonary interleukin 1 beta/serum amyloid A3 axis promotes lung metastasis of hepatocellular carcinoma by facilitating the pre-metastatic niche formation

GBA1-dependent membrane glucosylceramide reprogramming promotes liver cancer metastasis via activation of the Wnt/β-catenin signalling pathway

Neutral ceramidase activity inhibition is involved in palmitate-induced apoptosis in INS-1 cells

Serum sphingosine negatively correlates with albumin predicting the risk of hepatocellular carcinoma

C1orf74 positively regulates the EGFR/AKT/mTORC1 signaling in lung adenocarcinoma cells

Characterization of Novel P-Selectin Targeted Complement Inhibitors in Murine Models of Hindlimb Injury and Transplantation

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