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Molecular mechanisms underlying protective effects of quercetin against mitochondrial dysfunction and progressive dopaminergic neurodegeneration in cell culture and MitoPark transgenic mouse models of Parkinson's Disease

Journal of neurochemistry, 2017-06, Vol.141 (5), p.766-782

2017

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Manganese-Induced Neurotoxicity: New Insights Into the Triad of Protein Misfolding, Mitochondrial Impairment, and Neuroinflammation

Frontiers in neuroscience, 2019-06, Vol.13, p.654-654

2019

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Mitochondria-targeted antioxidants for treatment of Parkinson's disease: Preclinical and clinical outcomes

Biochimica et biophysica acta, 2014-08, Vol.1842 (8), p.1282-1294

2014

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Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein

Science signaling, 2019-03, Vol.12 (572)

2019

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Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells

Science signaling, 2019-01, Vol.12 (563)

2019

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Prokineticin‐2 promotes chemotaxis and alternative A2 reactivity of astrocytes

Glia, 2018-10, Vol.66 (10), p.2137-2157

2018

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Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress signaling events

Neurobiology of disease, 2018-09, Vol.117, p.82-113

2018

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Mechanistic Interplay Between Autophagy and Apoptotic Signaling in Endosulfan-Induced Dopaminergic Neurotoxicity: Relevance to the Adverse Outcome Pathway in Pesticide Neurotoxicity

Toxicological sciences, 2019-06, Vol.169 (2), p.333-352

2019

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Modified CAR T cells targeting membrane-proximal epitope of mesothelin enhances the antitumor function against large solid tumor

Cell death & disease, 2019-06, Vol.10 (7), p.476-476, Article 476

2019

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Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease

Neurobiology of disease, 2016-09, Vol.93, p.96-114

2016

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Mitochondrial stress-induced H4K12 hyperacetylation dysregulates transcription in Parkinson’s disease

Frontiers in cellular neuroscience, 2024-08, Vol.18

2024

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Manganese and Vanadium Co-Exposure Induces Severe Neurotoxicity in the Olfactory System: Relevance to Metal-Induced Parkinsonism

International journal of molecular sciences, 2024-05, Vol.25 (10), p.5285

2024

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Impact of Environmental Risk Factors on Mitochondrial Dysfunction, Neuroinflammation, Protein Misfolding, and Oxidative Stress in the Etiopathogenesis of Parkinson’s Disease

International journal of molecular sciences, 2022-09, Vol.23 (18), p.10808

2022

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Prokineticin-2 upregulation during neuronal injury mediates a compensatory protective response against dopaminergic neuronal degeneration

Nature communications, 2016-10, Vol.7 (1), p.12932-18, Article 12932

2016

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Nanoneuromedicines for degenerative, inflammatory, and infectious nervous system diseases

Nanomedicine, 2015-04, Vol.11 (3), p.751-767

2015

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Emerging neurotoxic mechanisms in environmental factors-induced neurodegeneration

Neurotoxicology (Park Forest South), 2012-08, Vol.33 (4), p.833-837

2012

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Microglial immune regulation by epigenetic reprogramming through histone H3K27 acetylation in neuroinflammation

Frontiers in immunology, 2023-03, Vol.14, p.1052925-1052925

2023

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Mechanistic Insights Into Gut Microbiome Dysbiosis-Mediated Neuroimmune Dysregulation and Protein Misfolding and Clearance in the Pathogenesis of Chronic Neurodegenerative Disorders

Frontiers in neuroscience, 2022-02, Vol.16, p.836605-836605

2022

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MitoPark transgenic mouse model recapitulates the gastrointestinal dysfunction and gut-microbiome changes of Parkinson’s disease

Neurotoxicology (Park Forest South), 2019-12, Vol.75, p.186-199

2019

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Vanadium exposure induces olfactory dysfunction in an animal model of metal neurotoxicity

Neurotoxicology (Park Forest South), 2014-07, Vol.43, p.73-81

2014

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Mito-metformin protects against mitochondrial dysfunction and dopaminergic neuronal degeneration by activating upstream PKD1 signaling in cell culture and MitoPark animal models of Parkinson's disease

Frontiers in neuroscience, 2024-02, Vol.18, p.1356703-1356703

2024

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High-Yield α-Synuclein Purification and Ionic Strength Modification Pivotal to Seed Amplification Assay Performance and Reproducibility

International journal of molecular sciences, 2024-06, Vol.25 (11), p.5988

2024

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PKC Delta Activation Promotes Endoplasmic Reticulum Stress (ERS) and NLR Family Pyrin Domain-Containing 3 (NLRP3) Inflammasome Activation Subsequent to Asynuclein-Induced Microglial Activation: Involvement of Thioredoxin-Interacting Protein (TXNIP)/Thioredoxin (Trx) Redoxisome Pathway

Frontiers in aging neuroscience, 2021-07, Vol.13, p.661505-661505

2021

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Fyn Kinase-Mediated PKCδ Y311 Phosphorylation Induces Dopaminergic Degeneration in Cell Culture and Animal Models: Implications for the Identification of a New Pharmacological Target for Parkinson's Disease

Frontiers in pharmacology, 2021-04, Vol.12, p.631375

2021

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New protocol for kinetic assay seeding ability recovery "KASAR" from formalin-fixed paraffin-embedded tissues

Frontiers in molecular biosciences, 2023-01, Vol.10, p.1087982-1087982

2023

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Molecular mechanisms underlying protective effects of quercetin against mitochondrial dysfunction and progressive dopaminergic neurodegeneration in cell culture and MitoPark transgenic mouse models of Parkinson's Disease

Manganese-Induced Neurotoxicity: New Insights Into the Triad of Protein Misfolding, Mitochondrial Impairment, and Neuroinflammation

Mitochondria-targeted antioxidants for treatment of Parkinson's disease: Preclinical and clinical outcomes

Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein

Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells

Prokineticin‐2 promotes chemotaxis and alternative A2 reactivity of astrocytes

Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress signaling events

Mechanistic Interplay Between Autophagy and Apoptotic Signaling in Endosulfan-Induced Dopaminergic Neurotoxicity: Relevance to the Adverse Outcome Pathway in Pesticide Neurotoxicity

Modified CAR T cells targeting membrane-proximal epitope of mesothelin enhances the antitumor function against large solid tumor

Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease

Mitochondrial stress-induced H4K12 hyperacetylation dysregulates transcription in Parkinson’s disease

Manganese and Vanadium Co-Exposure Induces Severe Neurotoxicity in the Olfactory System: Relevance to Metal-Induced Parkinsonism

Impact of Environmental Risk Factors on Mitochondrial Dysfunction, Neuroinflammation, Protein Misfolding, and Oxidative Stress in the Etiopathogenesis of Parkinson’s Disease

Prokineticin-2 upregulation during neuronal injury mediates a compensatory protective response against dopaminergic neuronal degeneration

Nanoneuromedicines for degenerative, inflammatory, and infectious nervous system diseases

Emerging neurotoxic mechanisms in environmental factors-induced neurodegeneration

Microglial immune regulation by epigenetic reprogramming through histone H3K27 acetylation in neuroinflammation

Mechanistic Insights Into Gut Microbiome Dysbiosis-Mediated Neuroimmune Dysregulation and Protein Misfolding and Clearance in the Pathogenesis of Chronic Neurodegenerative Disorders

MitoPark transgenic mouse model recapitulates the gastrointestinal dysfunction and gut-microbiome changes of Parkinson’s disease

Vanadium exposure induces olfactory dysfunction in an animal model of metal neurotoxicity

Mito-metformin protects against mitochondrial dysfunction and dopaminergic neuronal degeneration by activating upstream PKD1 signaling in cell culture and MitoPark animal models of Parkinson's disease

High-Yield α-Synuclein Purification and Ionic Strength Modification Pivotal to Seed Amplification Assay Performance and Reproducibility

PKC Delta Activation Promotes Endoplasmic Reticulum Stress (ERS) and NLR Family Pyrin Domain-Containing 3 (NLRP3) Inflammasome Activation Subsequent to Asynuclein-Induced Microglial Activation: Involvement of Thioredoxin-Interacting Protein (TXNIP)/Thioredoxin (Trx) Redoxisome Pathway

Fyn Kinase-Mediated PKCδ Y311 Phosphorylation Induces Dopaminergic Degeneration in Cell Culture and Animal Models: Implications for the Identification of a New Pharmacological Target for Parkinson's Disease

New protocol for kinetic assay seeding ability recovery "KASAR" from formalin-fixed paraffin-embedded tissues

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