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Complete integrin headpiece opening in eight steps

The Journal of cell biology, 2013-06, Vol.201 (7), p.1053-1068

2013

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Hsp47 promotes cancer metastasis by enhancing collagen-dependent cancer cell-platelet interaction

Proceedings of the National Academy of Sciences - PNAS, 2020-02, Vol.117 (7), p.3748-3758

2020

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Sequence and structure relationships within von Willebrand factor

Blood, 2012-07, Vol.120 (2), p.449-458

2012

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Chaperone Hsp47 Drives Malignant Growth and Invasion by Modulating an ECM Gene Network

Cancer research (Chicago, Ill.), 2015-04, Vol.75 (8), p.1580-1591

2015

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The importance of N-glycosylation on β3 integrin ligand binding and conformational regulation

Scientific reports, 2017-07, Vol.7 (1), p.1-14, Article 4656

2017

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Closed headpiece of integrin αIIbβ3 and its complex with an αIIbβ3-specific antagonist that does not induce opening

Blood, 2010-12, Vol.116 (23), p.5050-5059

2010

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Structural basis for PECAM-1 homophilic binding

Blood, 2016-02, Vol.127 (8), p.1052-1061

2016

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Family-wide analysis of integrin structures predicted by AlphaFold2

Computational and structural biotechnology journal, 2023-01, Vol.21, p.4497-4507

2023

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Structural Evidence for Loose Linkage between Ligand Binding and Kinase Activation in the Epidermal Growth Factor Receptor

Molecular and Cellular Biology, 2010-11, Vol.30 (22), p.5432-5443

2010

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The Role of Sialylated Glycans in Human Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1)-mediated Trans Homophilic Interactions and Endothelial Cell Barrier Function

The Journal of biological chemistry, 2016-12, Vol.291 (50), p.26216-26225

2016

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Antibodies causing thrombocytopenia in patients treated with RGD-mimetic platelet inhibitors recognize ligand-specific conformers of αIIb/β3 integrin

Blood, 2012-06, Vol.119 (26), p.6317-6325

2012

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Csk/CD148 and platelet SFK activation: a balancing act

Blood, 2018-03, Vol.131 (10), p.1042-1043

Zhu, Jieqing

2018

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Structural determinants of the integrin transmembrane domain required for bidirectional signal transmission across the cell membrane

The Journal of biological chemistry, 2021-11, Vol.297 (5), p.101318-101318, Article 101318

2021

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Identification of amino acid domains of Borrelia burgdorferi P66 that are surface exposed and important for localization, oligomerization, and porin function of the protein

Frontiers in cellular and infection microbiology, 2022-09, Vol.12, p.991689-991689

2022

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Measurement of Integrin Activation and Conformational Changes on the Cell Surface by Soluble Ligand and Antibody Binding Assays

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2217, p.3

2021

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Epirubicin potentiates recombinant adeno-associated virus type 2/5-mediated TRAIL expression in fibroblast-like synoviocytes and augments the antiarthritic effects of rAAV2/5-TRAIL

Arthritis & rheumatology (Hoboken, N.J.), 2012-05, Vol.64 (5), p.1345-1354

2012

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Tests of the Extension and Deadbolt Models of Integrin Activation

The Journal of biological chemistry, 2007-04, Vol.282 (16), p.11914-11920

2007

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Platelet Activation and Thrombus Formation over IgG Immune Complexes Requires Integrin αIIbβ3 and Lyn Kinase

PloS one, 2015, Vol.10 (8), p.e0135738

2015

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Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition

BMC cancer, 2014-01, Vol.14 (1), p.1-1, Article 1

2014

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In vivo dynamics of T cells and their interactions with dendritic cells in mouse cutaneous graft-versus-host disease

Blood advances, 2019-07, Vol.3 (14), p.2082-2092

2019

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Prolyl-4-hydroxylase [alpha] subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition

BMC cancer, 2014-01, Vol.14

2014

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Coagulopathy in COVID-19 and anticoagulation clinical trials

Best practice & research. Clinical haematology, 2022-09, Vol.35 (3), p.101377-101377, Article 101377

2022

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A pivotal role for a conserved bulky residue at the α1-helix of the αI integrin domain in ligand binding

The Journal of biological chemistry, 2017-12, Vol.292 (50), p.20756-20768

2017

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A general chemical principle for creating closure-stabilizing integrin inhibitors

Cell, 2022-09, Vol.185 (19), p.3533-3550.e27

2022

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Integrated extracellular matrix signaling in mammary gland development and breast cancer progression

Histology and histopathology, 2014-09, Vol.29 (9), p.1083

2014

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Complete integrin headpiece opening in eight steps

Hsp47 promotes cancer metastasis by enhancing collagen-dependent cancer cell-platelet interaction

Sequence and structure relationships within von Willebrand factor

Chaperone Hsp47 Drives Malignant Growth and Invasion by Modulating an ECM Gene Network

The importance of N-glycosylation on β3 integrin ligand binding and conformational regulation

Closed headpiece of integrin αIIbβ3 and its complex with an αIIbβ3-specific antagonist that does not induce opening

Structural basis for PECAM-1 homophilic binding

Family-wide analysis of integrin structures predicted by AlphaFold2

Structural Evidence for Loose Linkage between Ligand Binding and Kinase Activation in the Epidermal Growth Factor Receptor

The Role of Sialylated Glycans in Human Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1)-mediated Trans Homophilic Interactions and Endothelial Cell Barrier Function

Antibodies causing thrombocytopenia in patients treated with RGD-mimetic platelet inhibitors recognize ligand-specific conformers of αIIb/β3 integrin

Csk/CD148 and platelet SFK activation: a balancing act

Structural determinants of the integrin transmembrane domain required for bidirectional signal transmission across the cell membrane

Identification of amino acid domains of Borrelia burgdorferi P66 that are surface exposed and important for localization, oligomerization, and porin function of the protein

Measurement of Integrin Activation and Conformational Changes on the Cell Surface by Soluble Ligand and Antibody Binding Assays

Epirubicin potentiates recombinant adeno-associated virus type 2/5-mediated TRAIL expression in fibroblast-like synoviocytes and augments the antiarthritic effects of rAAV2/5-TRAIL

Tests of the Extension and Deadbolt Models of Integrin Activation

Platelet Activation and Thrombus Formation over IgG Immune Complexes Requires Integrin αIIbβ3 and Lyn Kinase

Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition

In vivo dynamics of T cells and their interactions with dendritic cells in mouse cutaneous graft-versus-host disease

Prolyl-4-hydroxylase [alpha] subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition

Coagulopathy in COVID-19 and anticoagulation clinical trials

A pivotal role for a conserved bulky residue at the α1-helix of the αI integrin domain in ligand binding

A general chemical principle for creating closure-stabilizing integrin inhibitors

Integrated extracellular matrix signaling in mammary gland development and breast cancer progression

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